Award Data

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The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Development of digital and interactive methods to teach immunology

    SBC: FLUID CONTENT INC            Topic: NIGMS

    Abstract The goal of this project is to develop a digital media based program to teach high school student about immunologyWe will develop an interactive digital media to teach minority studentshigh schoolon the introduction of immunology and compare the efficacy of learning between traditional teaching and interactive mediaWe will develop three curriculums to teach group of high school students r ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. Development of group 2 influenza A virus entry inhibitors

    SBC: Chicago Biosolutions, Inc.            Topic: NIAID

    Influenza A viruses belong to the Orthomyxoviridae family with a negative sensesegmented RNA genomewhich can cause seasonal or pandemic flu with high morbidity and significant mortalityVaccination is the most prevalent prophylactic means for controlling influenza infectionsHoweveran effective vaccine usually takes at leastmonths to develop for the circulating strainsFurthermorevaccination has limi ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Wireless, implantable optofluidic systems for programmed pharmacology and optogenetics

    SBC: Neurolux, Inc.            Topic: 101

    Project Summary Abstract Neuroscience research over the last decade has been revolutionized by many technological advancementsPharmacology and optogenetics represent two distinctand sometimes complementary tools used in neuroscience research to study the central and peripheral nervous systems in the context of the BRAIN initiativeAdvanced interrogations of underlying neural circuits and biology ar ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Monochromatic 222 nm UV light: Development of a safe, cost-effective technology for the efficient reduction of bacterial and viral infection and transmission

    SBC: EDEN PARK ILLUMINATION, INC.            Topic: NIAID

    Drug resistant bacteria such as MRSAand airborne transmitted microbes such as influenza and TBpresent significant health issueswith major healthcare and economic consequencesUV light is a well established highly efficient anti microbial modalityeffective both against both bacteria and virusesHowever it is not possible to use UV sterilization in scenarios where people are present because it is both ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Developing a peptide-based oral drug to prevent kidney stones

    SBC: Oxalo Therapeutics, Inc.            Topic: 400

    Project Summary Abstract Kidney stonesKSare highly prevalentexcruciatingand associated with long term complications of chronic kidney diseaseCKDand end stage renal diseaseESRDThey account forM ER visits and andgt $B of medical costs annually and have a striking recurrence rate ofinyears and up toinyearsreflecting the inadequacies of current interventionsof KS are composed of calcium oxalate and sm ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Development of a Personalized Bioreactor for Cell Culturing in Alginate Tubes

    SBC: CellGro Technologies, LLC            Topic: 400

    PROJECT SUMMARY ABSTRACT SignificanceCell therapy is expected to become an important method to treat chronic diseases such as diabetesrheumatoid arthritisretinal diseases like macular degeneration and certain types of cancersThe cell therapy market in general is projected to become a $billion industry byHuman pluripotent stem cellshPSCsare of particular importance since their utility as a source f ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. 4-(Aminomethyl) benzamides as novel anti-Ebola agents

    SBC: Chicago Biosolutions, Inc.            Topic: NIAID

    EbolaEBOVand MarburgMARVviruses belong to the Filoviridae family and can cause fatal hemorrhagic fevers characterized by widespread tissue destruction after an incubation period ofdaysDue to safety concernsthese viruses are designated as biosafety levelagentsCurrentlythere is no effective vaccine or therapeutic treatment for filoviral infections in humansAfrica has recentlysuffered a lethal EBOV e ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Advanced Multi-Modal Wearable Sensing for the Prediction of Pre-Term Labor

    SBC: Sonica LLC            Topic: NICHD

    Preterm birthPTBdelivery prior toweeks gestational ageaccounts forof all births and remains the leading cause of neonatal deathThe majority of PTB is preceded by spontaneous preterm laborPTLCurrentlythere is a major unmet need for methods to identify women at risk of PTL and provide an early warning system for potential interventionhome uterine monitoringHUMis one approach that has shown some prom ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Developing Insulin-like growth factor binding protein 2(IGFBP2)peptide fragment-based therapeutics to treat functional and behavioral deficits in Phelan-McDermid Syndrome.

    SBC: ALISBIO LLC            Topic: 101

    ABSTRACTAlisBio is developing novel therapeutics based on Insulin like growth factor binding proteinIGFBPpeptide fragments to treat functional and behavioral deficits in Phelan McDermid SyndromePMSa monogenic form of autism spectrum disorderASDaccounting forof ASD diagnosesThe focus of this Phase I grant is to demonstrate that proprietary IGFBPmimetic peptide fragments reverse disease relevant cel ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Array Based Affinity Selection

    SBC: Tango Biosciences Inc.            Topic: 300

    Project SummaryAffinity reagents are useful tools for detectingmonitoringand quantifying individual proteins in complex mixturesModern recombinant biology and protein engineering techniques generate highaffinityhigh specificity reagents that overcome some of the limitations of polyclonal and monoclonal antibodiesHoweverlimited availability of target proteini eantigenprevents the selection of recom ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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