Award Data

PROJECT SUMMARY Actively involving informal caregivers in direct patient care at the bedside in the intensive care unit (ICU) has the potential to improve patient, informal caregiver, and health care system outcomes. Practice guidelines call for the liberal inclusion of informal caregivers as active partners in ICU care, but there is a critical, unmet need to develop tools that effectively operati ...

Abstract Currently, clinically used drug abuse medications exist for treatment of addiction to opiates, alcohol, and nicotine, but not psychostimulants, such as methamphetamine (METH). Compounds that co-activate both nociceptin opioid peptide (NOP) and mu receptors have potential for treatment of drug abuse. In particular, buprenorphine, a partial mu agonist/kappa antagonist, which also acts as a ...

Project Summary and Abstract The most common neurogenic voice disorder is unilateral vocal fold paralysis (UVFP), which can substantially reduce quality of life. Current available surgical treatments offer only temporary improvement in voice through placement of resorbable materials or involve permanent, invasive alteration of the larynx that incompletely restores voice and often requires revision ...

PROJECT SUMMARYThe goal of this proposal is to optimize and clinically validate a new diagnostic test for eosinophilic chronic rhinosinusitis (eCRS) at the point-of-care, improving the efficiency, value, and accessibility of personalized medicine. eCRS affects up to 5 million Americans and is characterized by varying degrees of sinonasal and peripheral eosinophilia, linked to treatment responsiven ...

Currently, all JP10 is produced from fossil sources. The objective of the proposed project is to develop a scalable synthetic approach to producing JP-10 that meets military specification, MIL-DTL-87107E from non-fossil sustainable energy resources. During phase I, we will define, develop, and perform initial laboratory assessment of the proposed synthetic process to validate the technical feasi ...

Hemp-based clothing are excellent for outdoor active wear, due to high strength, UV-protective qualities, mold resistance, and excellent moisture absorption and desorption. While academic research on hemp-based textiles in the US is increasing, it has naturally also become an area of interest to competing countries. Specifically, China is outperforming the US in hemp fiber technological advancemen ...

Traditionally, small platforms that need to communicate with airborne platforms use omnidirectional antennas. This makes it simple to communicate with mobile airborne platforms but reduces the communication link range compared to directional antennas. However, directional antennas require pointing at the airborne platform, which requires a means of moving the antenna to follow the motion of the ai ...

Summary/Abstract Genomic sequencing is rapidly becoming a standard tool in diagnosing complex diagnostic cases, especially in critically ill newborns, and patients suffering from rare diseases. Current programs focused on addressing these cases utilise a team-based approach to identify, interpret and evaluate a patient’s genetic variants. These diverse teams include bioinformaticians, medical ge ...

PROJECT SUMMARY—More than 2 million Americans are hospitalized each year with bone fractures, and many more undergo outpatient procedures for fracture reduction and fixation. Some injuries can be treated with closed reduction and splinting or casting to immobilize the bone during healing. However, at some sites, more than half of fractures require open reduction and internal fixation. Despite ad ...

Hemp-based clothing are excellent for outdoor active wear, due to high strength, UV-protective qualities, mold resistance, and excellent moisture absorption and desorption. While academic research on hemp-based textiles in the US is increasing, it has naturally also become an area of interest to competing countries. Specifically, China is outperforming the US in hemp fiber technological advanceme ...