Award Data

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY19 is not expected to be complete until June, 2020.

  1. Translational development of specialized NK cells for cancer immunotherapy

    SBC: Indapta Therapeutic            Topic: 102

    Project Summary Abstract The annual incidence of head and neck cancers worldwide is more thancases with arounddeaths each yearand it is estimated that inthere will benew cases of non Hodgkin lymphoma with an estimateddeaths this yearIn this proposalwe describe a strategy to use a novel subset of natural killer cellsg NK cellsallogeneically for cancer therapyWe hypothesize that expansion and adopti ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. A Device to Inhibit Heterotopic Ossification

    SBC: IN SITU THERAPEUTIC SOLUTIONS INC            Topic: NIAMS

    PROJECT SUMMARY ABSTRACT Heterotopic ossificationHOis defined by bone formation in soft tissue and is a frequent debilitating complication of surgical procedures required by musculoskeletal and neurological injuriesUnfortunatelyit is not possible to accurately predict which patients will develop symptomatic HOwhich is characterized by pain and impaired functionThe current prophylactic standard of ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. PIXUL-FFPE:High throughput platform for chromatin and DNA sample preparation from formalin fixed paraffin embedded (FFPE) tissue samples.

    SBC: Matchstick Technologies Inc.            Topic: 172

    Formalin fixed paraffin embeddedFFPEtissue archives represent the largest clinically annotated human specimen repositoryThe estimated millions of available FFPE tissue samples provide vast resource for the discovery of disease epigenetic pathwaysbiomarkers and drug targetsAnd yetthese samples are highly underutilized because current methods for extracting molecular information from FFPE samples ar ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Development of a Personalized Bioreactor for Cell Culturing in Alginate Tubes

    SBC: CellGro Technologies, LLC            Topic: 400

    PROJECT SUMMARY ABSTRACT SignificanceCell therapy is expected to become an important method to treat chronic diseases such as diabetesrheumatoid arthritisretinal diseases like macular degeneration and certain types of cancersThe cell therapy market in general is projected to become a $billion industry byHuman pluripotent stem cellshPSCsare of particular importance since their utility as a source f ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Automated Health Assessment through Mobile Sensing and Machine Learning of Daily Activities

    SBC: Adaptelligence LLC            Topic: NIBIB

    PROJECT SUMMARY ABSTRACTAdvances in health care have been dramatic since the beginning of the millenniumAs a resultpeople are living longer with age related diseasesand the number of older individuals unable to live independently is rising rapidlyMobile computing offers an unprecedented opportunity to unobtrusively monitor behavior and use the large amount of collected data to automate analysis of ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. ASCEND, Accelerating Solutions for Commercialization and Entrepreneurial Development in the Mountain West IDeA States

    SBC: VIRTICI LLC            Topic: NIGMS

    Project Summary The objective of this proposal is to create a Mountain West region technology Accelerator Hub to conduct research on developingimplementingand testing a comprehensive collateral and consulting offering for promoting biomedical entrepreneurshiptechnology transfermanagementsmall business financeand additional business skills needed to commercialize basic research to enhance human hea ...

    STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Development of a Spirulina-based oral malaria vaccine

    SBC: Lumen Bioscience, Inc.            Topic: NIAID

    ABSTRACT Vaccination represents the single most effective and cost effective medical intervention devised to datesaving lives and reducing morbidity and disability for billions of humansDespite the early success of the oral polio vaccinemost vaccines are delivered parenterallyand as such are associated with painnon compliancebiohazardous medical waste and strict requirements for expensive producti ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Highly Sensitive Chimerism Testing to Detect Early Leukemia Relapse Post-Allo-Transplantation

    SBC: Chimerocyte, Inc.            Topic: 102

    ABST RACT Patients with acute blood malignancies who undergo allogeneic hematopoietic stem cell transplantationHSCTare monitored for minimal residual diseaseMRDas predictive of relapseIncreasing mixed chimerismreemerging recipient cellscorrelates with reappearance of underlying disease by association with MRDGenetic and immunophenotypic heterogeneity of these malignancies often prevents establishi ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. CruziScreen a recombinant antigen based screening test for Chagas disease

    SBC: PAI Life Sciences, Inc.            Topic: NIAID

    Project Summary Chagas disease is a severe inflammatory syndrome caused by infection with a protozoan parasite Trypanosoma cruzi Although transmission occurs mostly through an intermediate insect host the infection is silent and chronic carriers pose a significant risk through the transfer of infected products made from donated blood of these individuals to blood recipients Up to new c ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  10. TRANSCRANIAL DOPPLER SIMULATOR FOR TRAINING AND ASSESSMENT

    SBC: Sheehan Medical LLC            Topic: 101

    We aim to develop a transcranial Doppler TCD ultrasound simulator on a physical mannequin for realistic medical training and professional competence testing The Specific Aims of the project are Develop a prototype TCD simulator The anatomy of the cerebrovascular system CVS will be reconstructed in three dimensional D from a patient s computed tomography angiogram CTA The blood flow ...

    STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
US Flag An Official Website of the United States Government