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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Autism Treatment The Pivotal Skills Trainer

    SBC: ACCELERATIONS EDUCATIONAL SOFTWARE            Topic: N/A

    DESCRIPTION (provided by applicant): This STTR (Phase 1) project begins the translation of untapped scientific findings into an improved software tool for teaching children with autism spectrum disorders and other disabilities. The project evaluates a package to train teachers to use software called the Pivotal Skills Trainer and examines whether doing so improves preschoolers' functional communic ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  2. Autism Education and Treatment with PowerPoint Software

    SBC: ACCELERATIONS EDUCATIONAL SOFTWARE            Topic: N/A

    DESCRIPTION (provided by applicant): PowerPoint(R) multimedia software is ubiquitous in our schools but its capacity for teaching children with autism spectrum and related disorders barely has been realized. This STTR (Phase I) project will begin to change this state of affairs by researching and developing empirically derived multimedia teaching tools. Encouraged by early-stage feasibility work, ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  3. Modified HER-2 Tumor Antigens for Vaccination in Cancer

    SBC: L2 DIAGNOSTICS LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The proposed studies are aimed at developing a new tumor immunotherapy by using isoaspartyl-modified peptides to break immune tolerance to "self" tumor antigens on breast cancer cells. Most tumor antigens have been characterized as normal, non-mutated self-peptides, linking the concepts of autoimmunity with the development of tumor immunity. Previous studies de ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  4. Isoaspartyl Modified Tumor Antigens for Vaccination

    SBC: L2 DIAGNOSTICS LLC            Topic: N/A

    DESCRIPTION (provided by applicant): This proposal will take advantage of several unique observations made in understanding the properties of self proteins that regulate the development of autoimmune responses. In attempts to define cryptic self peptides of lupus autoantigens, we found that a particular post-translational modification of a self peptide elicited strong B and T cell autoimmunity. T ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  5. Virulence Typing of Pseudomonas Clinical Isolates

    SBC: L2 DIAGNOSTICS LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Pseudomonas aeruginosa is an opportunistic bacterial pathogen responsible for a significant proportion of serious hospital acquired infections. The organism has intrinsic resistance to most types of antibiotics and can readily acquire resistance to all clinically available antimicrobials, resulting in infections that are impossible to treat. P. aeruginosa colo ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  6. Preclinical development of the tsetse thrombin inhibitor

    SBC: L2 DIAGNOSTICS LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Thromboembolic disease is a major cause of morbidity and mortality in the developed world. Despite the need for effective therapies for treating and preventing pathologic activation of thrombosis, there are relatively few currently available alternatives to intravenous heparin. The total commercial market for antithrombotic agents has been estimated at 2 billio ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  7. A Novel High-Intensity Area X-ray Source

    SBC: Nesch, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Diffraction enhanced imaging (DE I) is a novel approach to X-ray imaging, which can revolutionize X-ray medical imaging, because of its greater contrast at lower X-ray doses than conventional radiography. DEI relies on measuring tiny angular deflections of a collimated X -ray beam as it passes through the object (patient) in acquiring the images. The capabil ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  8. Large-area X-ray diffraction crystal optics

    SBC: Nesch, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Diffraction enhanced imaging (DEI) is a novel approach to X-ray imaging which can revolutionize X -ray medical imaging, because of its greater contrast at lower X-ray doses than conventional radiography. DEI relies on X-ray optics of perfect crystals to acquire these images by measuring tiny angular deflections of a collimated X-ray beam as it pass es throug ...

    STTR Phase I 2004 Department of Health and Human ServicesNational Institutes of Health
  9. Surface Films to Suppress Field Emission in High-Power Microwave Components

    SBC: Omega-P, Inc.            Topic: 7

    75119-The achievement of high microwave fields in next-generation high-energy particle accelerators will require, among other things, that field emission and breakdown be held to within strict upper limits. One means to achieve this goal is to devise rugged thin-film coatings for vulnerable copper surfaces, providing a higher work function than copper alone. This project will evaluate a variety ...

    STTR Phase I 2004 Department of Energy
  10. RF Gun with High-Current-Density Field Emission Cathode

    SBC: Omega-P, Inc.            Topic: 5

    75748-Cathodes have a dominant influence on the quality of the electron beams produced from laser photo-cathodes in radio frequency (rf) guns used as injectors in many electron accelerators. Similar limitations are also suffered by thermionic cathodes in diode guns used in high-power rf amplifiers for accelerator applications. These limitations could be surmounted by a field-emission cold cathod ...

    STTR Phase I 2004 Department of Energy
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