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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Discovery of Zika virus therapeutics using a replicon assay
SBC: MICROBIOTIX, INC. Topic: RABSTRACT The Zika virusZIKVis the cause of an explosive pandemic of infections across South and Central Americathe Caribbeanand the southeastern region of the United StatesZIKV is a flavivirusa family of small positive strand RNA viruses that includes Dengue virusDENVWest Nile virusWNVYellow fever virusYFVand hepatitis C virusHCVZIKV is transmitted to humans by mosquitoes of the Aedes genusFor the ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Intravascular molecular-structural NIRF-IVUS imaging of coronary artery disease
SBC: IntraVascular Imaging, Inc. Topic: NHLBIThe goal of this Phase I STTR project is to constructoptimizeand test a clinically viable intravascular near infrared fluorescence intravascular ultrasoundNIRF IVUSimaging catheter for simultaneous molecular and structural diagnosis of coronary artery diseaseCADCAD is a worldwide leading cause of death and disabilityincluding acute myocardial infarctioncongestive heart failureand sudden cardiac de ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Nucleobase aminosugars with reduced ototoxicity
SBC: NUBAD LLC Topic: YPROJECT SUMMARYAminoglycosides are one of the cheapest and well known antibiotics in clinical use for overyearsbut one of the major limitations in their use is their ototoxicityWe are developing fast and low cost methods to develop aminoglycosides with antiribosomal activities and reduced toxicityIn this projectwe will identify novel aminoglycoside antibacterialsthat show reduced ototoxicityComple ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Exploration of Low-Cost Long-Timescale Free Energy Perturbations on FPGAs
SBC: Silicon Insite, Inc. Topic: 400Drug discovery is challenging and expensiveespecially in the phase of lead optimization whichpredicts binding to a targetComputational approaches can add substantial valueComputingrelative binding free energiesRBFEbetween congeneric molecules using molecular dynamicsMDgreatly reduces the search space and considerably improves convergenceThe Silicon TherapeuticsSTXINSITE platform uses an RBFE proto ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Formation and Structural Property Relationships of a Tetracalcium Phosphate Bone Adhesive Biomaterial
SBC: REVBIO, INC. Topic: NIAProject Abstract Approximatelyof all fractures occur in the small bones of the wristshands and feetamounting to more thanmillion annuallyConsidering functional losses associated with the locations of these injuriesproper reduction and fixation is critical to ensure optimal rehabilitation and recoveryComplex injuries that include irreducible fractures or segmental bone loss require operative fixati ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
A Mobile Tai Chi Platform for Fall Prevention in Older Adults
SBC: BIOSENSICS LLC Topic: NIAProject Summary The overall goal of the proposed work is to develop a platform capable of delivering and monitoring adherenceproficiencyand safety of a home based simplified Tai Chi intervention for older adultsDuring Phase I of this Fast Track STTR project we will further develop a novel approach to assessing Tai Chi performance adherenceproficiencyand safety based on wearable sensor dataMetrics ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Toward Automated Spike Sorting via Ground Truth Neural Recordings
SBC: Leaflabs, LLC Topic: 101PROJECTSUMMARY Scaling extracellular electrophysiology to higher channel counts is hindered by the burden of data handling storageand especially preprocessinge gspike sortingThe burden of spike sorting can in principle be reduced through a combination of high density multielectrode arrayprobetechnology and algorithm optimization to yield a spike sorting method that is both highly accurate and full ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Developing a Novel Digital Therapeutic for the Treatment of Generalized Anxiety Disorder
SBC: GOBLUE INTERNATIONAL, LLC Topic: 104Abstract Worry is a habitual thought process that is observed in individuals with anxiety disordersA leading theory posits that although worrying may be unpleasantthe immediate emotions that are avoided by concentrating on worry are often perceived as more aversiveegfearangergriefFrom a mechanistic perspectiveworry is thought to be learned and reinforced in a similar manner to other types of opera ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
Design of Protease Stable Therapeutic Peptides by Non-Perturbative Modification
SBC: VELUM INC Topic: 300PROJECT SUMMARY! Peptide therapeutics combine high potency and selectivityand engender fewer side effects than traditional small moleculesThis has fueled interest in peptides filling the gap between `biologicsandaposand small molecules as compounds that have key desired properties from both the other classesThere are however some challengesthe major one being susceptibility to enzyme catalyzed hyd ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health -
An Innovative Platform for Objective Monitoring of Instrumental Activities of Daily Living
SBC: BIOSENSICS LLC Topic: NIAABSTRACT With a Phase I II STTR grant award from NIABioSensics in collaboration with Baylor College of MedicineBCMsuccessfully developed and commercialized an advanced physical activity monitoring systemPAMSysfor older adultsPAMSys enables continuous remote monitoring of physical activityfall riskand fall incidentsThe fall detection technology of PAMSys has become the gold standard in the medical ...
STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health