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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Mapping disease-specific human protein networks

    SBC: Curagen Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): While the human genome sequence is known, medical advances will require knowledge of how individual genes and proteins assemble into functional biological networks. These networks are built in part through physical interactions between proteins. Protein interaction networks can now be probed using highthroughput experimental methods, yet challenges remain: dat ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  2. Development of a Genetic Therapy for CF in a CF Rabbit

    SBC: EVERGEN BIOTECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The development of transgenic mouse models for cystic fibrosis (CF) has been an important contribution to our understanding of CF and of CF transmembrane conductance regulator (CFTR) function. However, because of the dissimilarity between mouse and human anatomy and physiology, there are limitations in what can be discerned about CF pathology and in development ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  3. Virulence Typing of Pseudomonas Clinical Isolates

    SBC: L2 DIAGNOSTICS LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Pseudomonas aeruginosa is an opportunistic bacterial pathogen responsible for a significant proportion of serious hospital acquired infections. The organism has intrinsic resistance to most types of antibiotics and can readily acquire resistance to all clinically available antimicrobials, resulting in infections that are impossible to treat. P. aeruginosa colo ...

    STTR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  4. Protection Against West Nile Virus by RNA Interference

    SBC: L2 DIAGNOSTICS LLC            Topic: N/A

    DESCRIPTION (provided by applicant): West Nile (WN) virus is a flavivirus that can cause fatal human encephalitis. Over the past four years, this virus has established itself across the United States. There are no approved vaccines or therapies to protect against WN virus. This project is designed to develop an effective anti-WN virus RNA interference therapy. Our hypothesis is that small interfer ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  5. Investigation of Shape Memory Polymers in Orthodontics

    SBC: New Ortho Polymers            Topic: N/A

    DESCRIPTION (provided by applicant): All orthodontic treatment is based on the application of optimal forces that minutely displace teeth initiating a biological response that alters both hard and soft tissues. Because of the precision of control, most treatment is carried out with fixed appliances that are capable of delivering forces and moments to the crowns of teeth. More limited treatment an ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  6. OTOREFLECTANCE ASSESSMENT OF MIDDLE-EAR FUNCTIONING

    SBC: Sonicom, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Otoreflectance (OR) is a new class of hearing-test instruments utilizing acoustic signals presented and recorded in the ear canal. OR instruments address the following limitations in existing instruments to screen and diagnose middle-ear function: (1) detection of otitis media, (2) prediction of conductive hearing loss, (3) detection of middle-ear dysfunction i ...

    STTR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
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