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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Backbone Degradable Polymer-drug Conjugates for the Treatment of Ovarian Cancer

    SBC: THERATARGET, INC.            Topic: NCI

    DESCRIPTION provided by applicant The purpose of this Phase II STTR project is to develop a polymeric system for the combination delivery of two antineoplastic agents gemcitabine and paclitaxel Based on the successful results of the STTR Phase I award this Phase II proposal details the rationale and research plan for the synthesis and evaluation of in vivo efficacy of two novel macromolecula ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Slip Flow Chromatography

    SBC: BIOVIDRIA, INC.            Topic: 100

    DESCRIPTION provided by applicant The goal of this STTR Phase II collaboration between Purdue University and bioVidria Inc is to commercialize disruptive new technology for protein chromatography and then maximize its impact by serving the fastest growing segment of the pharmaceutical industry protein drugs The product is a reversed phase chromatography column that uses silica particles of ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Scale up of EO polymers and their utilization in novel nano-imprinted sub-wavelength waveguide-based Modulators and Arrays

    SBC: TIPD LLC            Topic: AF11BT01

    ABSTRACT: The Phase II technical objectives follow directly from the Phase I effort, where all tasks necessary for RF photonic receiver fabrication were demonstrated. The Phase II effort will pursue two major objectives: 1) further development of SEO100 EO polymer based chips, packaged devices and arrays in collaboration with University of Dayton (antenna designs), taking advantage of multiphoto ...

    STTR Phase II 2014 Department of DefenseAir Force
  4. A Rapid assay for RNA targeted drugs: Instrumentation Supplement

    SBC: NUBAD LLC            Topic: 300

    DESCRIPTION provided by applicant Some of the most significant therapies that treat disease target nucleic acids Drugs that target nucleic acid include cancer drugs antibiotics and antivirals Combined these classes of drugs have annual sales worldwide of $ billion Antibiotics that target nucleic acids account for $ billion of the $ billion of sales annuall for all antibiotics an ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Development of Peptide Antibiotic Nucleic Acids

    SBC: NUBAD LLC            Topic: NIAID

    DESCRIPTION provided by applicant One of the challenges of research in infectious diseases is to find ways to use the increasing knowledge of the mechanisms underlying disease transformation and progression to develop novel therapeutic strategies for diseases such as increasing menace of bacterial infections Targeting specific RNA such as rRNA which are involved in proliferation and survival ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Commercialization of a Diagnostic test for amyotrophic lateral sclerosis (ALS)

    SBC: IRON HORSE DIAGNOSTICS, INC.            Topic: 101

    DESCRIPTION provided by applicant Amyotrophic lateral sclerosis ALS or Lou Gehrigandapos s disease is a fatal neurodegenerative disease with a typical lifespan of years after diagnosis The initial symptoms can be similar to many other neurologic disorders and often begin with limb weakness muscle fasciculations or increasing difficulties in speech or breathing No definitive diagnost ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Reversal of Myocardial Infarction by Localized Stimulation

    SBC: Micro Vide, LLC            Topic: NHLBI

    DESCRIPTION provided by applicant Heart attacks i e myocardial infarction or MI occur in more than million patients annually Advances in pharmacological therapy have dramatically improved survival following the initial MI Consequently the number of patients with previous MI continues to increase and as a result put in jeopardy millions of patients for development of heart failure I ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  8. High Power WDM Based Upon Mode Coupling

    SBC: ADVALUE PHOTONICS INC            Topic: AF13AT03

    ABSTRACT: AdValue Photonics and University of Arizona propose to demonstrate the capability of fabricating wavelength division multiplexers (WDM) for high-power fiber laser applications. It is based on AdValue Photonics"unique fused fiber technology using large-mode-area (LMA) fibers. Both polarization-maintaining (PM) and non-PM LMA fiber WDMs will be fabricated. By the end of Phase I, two proto ...

    STTR Phase I 2014 Department of DefenseAir Force
  9. Assessing the Bite Counter as a Tool for Food Intake Monitoring: Phase II

    SBC: BITE TECHNOLOGIES, LLC            Topic: 300

    DESCRIPTION provided by applicant Self monitoring has been described as the andquot cornerstone of the behavioral treatment of obesityandquot Consistent self monitoring of energy intake is associated with improved dietary adherence and weight loss and maintenance The problem is that individuals are notoriously bad at self monitoring their intake and suffer from an underreporting bias The s ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Sensitivity Analysis Methods for Complex, Multidisciplinary Systems

    SBC: ZONA TECHNOLOGY INC            Topic: AF11BT06

    ABSTRACT: The overall technical objective of this Phase II effort is to develop computational tools for computing response sensitivities of parametric multi-disciplinary air vehicle systems that exhibit nonlinear dynamic behavior for use in gradient-based optimization, smart sampling, uncertainty quantification, and risk assessment. To this end, the ZONA/MIT team will extend the 2-D ZEUS time-dom ...

    STTR Phase II 2014 Department of DefenseAir Force
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