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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Novel Inhibitors of Pim Protein Kinases
SBC: VORTEX BIOTECHNOLOGY CORPORATION Topic: N/ADESCRIPTION (provided by applicant): There is a growing body of evidence that implicates the protein kinase Pim-1 as a major driver of prostate cancer progression, and perhaps response to chemotherapy. Pim-1 is overexpressed in early prostate intraepithelial neoplasia and metastatic prostate cancer, and its levels predict response to therapy. Pim-1-overexpressing mouse prostate stem cells demonstr ...
STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health -
Acid Ceramidase, Target for Cancer
SBC: Sphingogene, Inc Topic: N/ADESCRIPTION (provided by applicant): Acid ceramidase (AC) has been implicated as a novel target for cancer therapy because of its pivotal role in regulating interconversion of three key bioactive lipids; ceramide (Cer), sphingosine (Sph) and Sphingosine-1-Phosphate (S1P). It is well known that Cer functions predominantly as a tumor suppressor lipid and mediator of apoptosis following chemo and rad ...
STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health -
Sensitive Microarray Slides Using Silica Colloidal Crystals
SBC: BIOVIDRIA, INC. Topic: N/ADESCRIPTION (provided by applicant): Microarrays have become indispensable tools in research and medicine. DNA microarrays are established as research tools, and they are expected to grow into clinical diagnostics. Higher sensitivity would advance this transition, while also benefiting research. Proteins report more directly on the biology than does DNA or mRNA, protein microarrays have now become ...
STTR Phase I 2009 Department of Health and Human ServicesNational Institutes of Health -
VISION: Volumetric Imaging for Science Instruction of an Open Nature
SBC: SCIENCE-APPROACH Topic: N/ADESCRIPTION (provided by applicant): The goal of this Phase II Small Business Technology Transfer (STTR) application-entitled Volumetric Imaging for Science Instruction of an Open Nature (VISION)-is to adapt an advanced technology employed in biomedical research and practice-volumetric image processing and analysis (VIPA)-for science and mathematics education in formal secondary school settings. ...
STTR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health -
Experimental Pharmacology and Chemical Studies of Nikkomycin Z
SBC: VALLEY FEVER THERAPIES LLC Topic: N/ANot Available
STTR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health -
Surface-covering gels for broad-spectrum antimicrobial protection following open
SBC: SONORAN BIOSCIENCES INC Topic: NIAMSDESCRIPTION (provided by applicant): About 3-4% of all fractures are estimated to be open fractures, where the fracture is exposed through defects in the skin and soft tissues. This equates to about 250,000 open fractures in the United States annually. Open fractures present a high risk of infection. Infection results in considerable financial burden to both the patient an healthcare system, requ ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Non-ATP competitive inhibitors of cyclin dependent kinases as cancer therapeutics
SBC: PPI PHARMACEUTICALS, LLC Topic: NCIDESCRIPTION (provided by applicant): As cancer is one of the leading causes of death in the United States with some sub-types remaining essentially untreatable, expansion of available drug targets will provide significant new options for the development ofmore effective antineoplastic agents. The major goal of this project is to apply a unique drug discovery strategy to cancer drug development. Th ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
A Millimeter-wave Tunable Cavity for Ultra-sensitive Solids and Liquids DNP-NMR at Low Budget
SBC: DOTY SCIENTIFIC, INC. Topic: NIA? DESCRIPTION (provided by applicant): NMR is probably the most powerful and widely used analytical technique for structure determination and function elucidation of molecules of all types, but it suffers from low sensitivity, particularly for insoluble biological macromolecules. Dynamic Nuclear Polarization (DNP) with Magic Angle Spinning (MAS) has recently demonstrated S/N gains exceeding t ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
TILLING wheat for reduced celiac disease causing proteins
SBC: Arcadia Biosciences, Inc. Topic: N/ADESCRIPTION (provided by applicant): Celiac disease is an autoimmune digestive disorder in which intestinal lesions develop in genetically susceptible individuals in response to the ingestion of specific cereal seed storage proteins. The only treatment is strict adherence to a diet free from the offending grains. Therefore, considerable research has been devoted to identifying the specific amino a ...
STTR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health -
Restoration of Skin Structure and Function Post-Wounding
SBC: FirstString Research, Inc Topic: N/ADESCRIPTION (provided by applicant): The wound repair process in skin is initiated immediately after an injury and induces a cascade of events including inflammation, proliferation, and scar differentiation. The adverse changes in skin structure and function resulting from scar tissue affects over 35 million US citizens a year resulting in costs of more than 7 billion dollars). The founders of Fir ...
STTR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health