Award Data

DESCRIPTION provided by applicant Intracerebral hemorrhage ICH is a major public health problem with highest mortality rate of all stroke subtypes and long term disability Since there are no available FDA approved therapies for ICH it is of enormous importance to establish effective treatment for this medical condition Following ICH the deposited blood is damaging initially via compression ...

DESCRIPTION provided by applicant Mass spectrometry based proteomics is an emerging technology that has seen possible applications everywhere The technique can potentially use one drop of our blood to reveal onset and progress of diseases Current Randamp D using plasma serum proteome sample sets however is severely limited by the high complexity and dynamic range of protein concentrations ...

DESCRIPTION provided by applicant Metastasis or dissemination of primary tumor cells is the major cause of mortality in cancer patients Circulating tumor cells CTCs in the bloodstream are key players in the establishment of metastatic tumors Recent studies demonstrated that the number of CTCs present in patient blood directly correlate with cancer progression recurrence and survival rate ...

Texas Research Institute Austin, Inc. (TRI/Austin) is developing a lithium-ion battery module that will manage individual cell thermal runaways in two ways. The active management path will be to monitor the internal temperature of the cell and remove the cell from the charging/discharging circuit if anode or cathode temperatures exceed specified temperatures. Removal from the charging/discharging ...

This effort proposes to design, develop and fabricate prototype SiGe MMICs that when combined with GaN MMICs forms the basis for additional simultaneous modes and more efficiency for the C-band Radar Automatic Collision Avoidance System (RACAS). The addition of these MMICs will enable digitally controlled pulse mode interleaving and switchable and simultaneous polarizations for enhanced Coherent A ...

DESCRIPTION provided by applicant The measurement monitoring and use of bioelectric signals has evolved from the measurement of the electrical activity of the heart to encompass tissues ranging from cardiac skeletal and smooth muscles to brain and peripheral nerve tissues Together with this development has been the evolution of specialized equipment to capture and interpret these minute sig ...

Nanohmics/UNC proposes the Argus-EC wide spectral band laser threat sensor, with capability to provide real-time gathering of data regarding laser radiation directed against instrumented military assets. The proposed team comprises Nanohmics, Inc., and the Center for Optoelectronics and Optical Communications at the University of North Carolina at Charlotte. The successful Phase I reduced the prim ...

Modern aircraft make extensive use of fasteners made of steel, titanium, nickel and other alloys mated with aluminum and composite airframe materials. This coupling of dissimilar materials yields galvanic corrosion issues, which degrades mechanical integrity, is costly to inspect, and poses a safety and reliability risk. Traditional design approaches of corrosion rate predictions based on open cir ...

DESCRIPTION provided by applicant Ovarian cancer is the fifth most leading cause of cancer related deaths in women in the US It has been observed that the cancer relapses within relatively short periods of time even after the surgery and chemotherapy Therefore immunotherapeutic strategies may serve as an alternative to control the recurrence or progression of ovarian cancer Oral vaccines ar ...

DESCRIPTION provided by applicant Some of the most significant therapies that treat disease target nucleic acids Drugs that target nucleic acid include cancer drugs antibiotics and antivirals Combined these classes of drugs have annual sales worldwide of $ billion Antibiotics that target nucleic acids account for $ billion of the $ billion of sales annuall for all antibiotics an ...