Award Data

DESCRIPTION provided by applicant For this Phase II STTR proposal the investigators plan to develop and commercialize the radiofrequency RF coil technology to make T body MRI possible and to translate this new technology to vastly improve T clinical MRI as well In the Phase I project leading to this proposal all specific aims were accomplished to demonstrate the feasibility of safely an ...

Advanced effective Micro-glider development will be conceived under this Phase I effort.

DESCRIPTION provided by applicant Some of the most significant therapies that treat disease target nucleic acids Drugs that target nucleic acid include cancer drugs antibiotics and antivirals Combined these classes of drugs have annual sales worldwide of $ billion Antibiotics that target nucleic acids account for $ billion of the $ billion of sales annuall for all antibiotics an ...

DESCRIPTION provided by applicant One of the challenges of research in infectious diseases is to find ways to use the increasing knowledge of the mechanisms underlying disease transformation and progression to develop novel therapeutic strategies for diseases such as increasing menace of bacterial infections Targeting specific RNA such as rRNA which are involved in proliferation and survival ...

DESCRIPTION provided by applicant Heart attacks i e myocardial infarction or MI occur in more than million patients annually Advances in pharmacological therapy have dramatically improved survival following the initial MI Consequently the number of patients with previous MI continues to increase and as a result put in jeopardy millions of patients for development of heart failure I ...

DESCRIPTION provided by applicant Self monitoring has been described as the andquot cornerstone of the behavioral treatment of obesityandquot Consistent self monitoring of energy intake is associated with improved dietary adherence and weight loss and maintenance The problem is that individuals are notoriously bad at self monitoring their intake and suffer from an underreporting bias The s ...

The Navy and Marine Corps currently protect their Data-at-Rest (DAR) storage using Public Key Infrastructure (PKI) encryption technology. PKI protects data based on a single security key pair allowing only a single individual to decrypt the data; thus making it unsuitable for an environment where multiple individuals, satisfying an access policy, would be able to decrypt the data. Therefore, Archi ...

DESCRIPTION (provided by applicant): Koronis Biomedical Technologies (KBT) proposes to develop a novel tunneling magnetoresistance (TMR) sensor for use in medical devices. TMR technology delivers improvements in magnetic sensor size, sensitivity, and noiserejection that represent an opportunity to significantly enhance the performance of a variety of medical devices that currently rely on traditio ...

DESCRIPTION (provided by applicant): One of the challenges of research in infectious diseases is to find ways to use the increasing knowledge of the mechanisms underlying disease transformation and progression to develop novel therapeutic strategies for AIDS. Targeting specific RNA- protein interactions, such as Tat-TAR or Rev-RRE, which are involved in proliferation and survival of HIV-1 is a pro ...

DESCRIPTION (provided by applicant): In this Phase I STTR project Koronis Biomedical Technologies (KBT) in close collaboration with the Zelazo Lab at the University of Minnesota proposes to develop an electroencephalography (EEG) based neurocognitive training tool to enable individuals to improve neurocognitive processes associated with executive function (EF). Processes involved in self-control a ...