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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Manufacturing pathogen inactivated platelet lysate to treat corneal inflammation
SBC: Cambium Medical Technologies LLC Topic: NDESCRIPTION provided by applicant Ocular graft versus host disease O GVHD is a particularly severe and debilitating complication of allogeneic hematopoietic stem cell transplantation HSCT O GVHD develops in of patients with chronic GVHD Currently Restasis cyclosporine A is the only FDA approved prescription topical medication to treat O GVHD In Restasis had sales o ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Selenium-derivatized New Reagents for Nucleic Acid X-ray Crystallography
SBC: SENA RESEARCH, INC. Topic: NIEHSDESCRIPTION provided by applicant There are growing demands for D structure determination of nucleic acids and their protein complexes for understanding disease molecule level mechanisms and discovering innovative drugs X ray crystallography is one of the most direct and powerful tools for structure determination of these macromolecules and complexes However the crystallization and phase d ...
STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health -
Custom Fit 3D-Printed Pediatric Respiratory Masks
SBC: ADVANCED MEDICAL ELECTRONICS CORP Topic: NICHDDESCRIPTION provided by applicant This project will develop an FDA approved process D printing system and advanced D printable material suitable for point of care manufacturing of custom fit continuous positive airway pressure CPAP masks for neonates In extremely low birth weight infants nasal CPAP therapy is delivered via soft biocompatible neonatal sized nasal masks suitable for lon ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Live-Cell Fluorescence Lifetime FRET Assays for HTS
SBC: Fluorescence Innovations, Inc. Topic: R42DESCRIPTION provided by applicant We seek to develop and commercialize a powerful technology platform to increase dramatically the effectiveness of drug discovery using high throughput screening HTS based on fluorescence lifetime FLT readouts of FRET in live cells This breakthrough is enabled by a combination of two complementary and synergistic technologies fluorescent biosensor engineer ...
STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health -
Distance Filtering System for Retinal Implants
SBC: ADVANCED MEDICAL ELECTRONICS CORP Topic: NDESCRIPTION provided by applicant We propose to develop and evaluate the utility of a novel input camera system for retinal prosthetics that allows users to filter optical imagery based on distance from the observer We call this andquot depth filteringandquot which can be accomplished with a depth sensing stereoscopic camera system Retinal prostheses can restore partial vision to people bli ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Access to Exercise Stress Testing for Elderly Native Americans in Remote Locations
SBC: ADVANCED MEDICAL ELECTRONICS CORP Topic: NDESCRIPTION provided by applicant Heart disease is the leading cause of death among elderly American Indians and Alaska Natives Heart disease death rates for elderly American Indians at per are percent higher than average in the total U S population Most elderly Native Americans live in remote locations and lack transportation to healthcare facilities This is a key barrie ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Anti-CXCL13 mAb to mitigate prostate cancer health disparities
SBC: JYANT Technologies, Inc. Topic: NIMHDDESCRIPTION provided by applicant The most common metastatic site for hormone refractory prostate cancer HRPC PCa is bone While docetaxel can prolong the overall survival in patients with metastatic HRPC current treatments do not provide a cure Further complicating the matter HRPC is a disease that affects a variety of patients differently which can be problematic for physicians to prov ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Directed Antifungal Therapy for HIV-associated Cryptococcal Meningitis
SBC: Minnetronix Medical, Inc. Topic: NIAIDDESCRIPTION provided by applicant Directed Antifungal Therapy for HIV associated Cryptococcal Meningitis PI Lad Shivanand and McCabe Aaron Project Summary Cryptococcosis is an important systemic mycosis and one of the most prevalent infectious diseases in human immunodeficiency virus HIV positive individuals Amongst the million people with HIV AIDS recent estimates indicate that there ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Development of a Novel Therapeutic Approach for Cryptococcal Meningitis
SBC: Minnetronix Medical, Inc. Topic: NIAIDDESCRIPTION provided by applicant When Cryptococcus is manifested as Cryptococcal meningitis CM it creates a large burden of mortality and morbidity to the patient and is very difficult for the clinician to treat There are now US cases and over million cases of CM worldwide annually with estimated deaths of per year CM is caused when Cryptococcus neoformans a basidiomyce ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Stroke Treatment by Chemically-induced Hypothermia
SBC: JT Pharmaceuticals, Inc. Topic: 101DESCRIPTION provided by applicant Stroke is a leading cause of human death and disability in the United States while clinical therapy for acute stroke is limited and unsatisfactoy The many failures in clinical trials strongly endorse the idea that to battle this multifaceted bran disorder novel strategies that target multiple cell types and different mechanisms are needed to achieve therapeut ...
STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health