Award Data

In Phase I we successfully reached all goals and milestones in developing liquid crystal sensors that detected 100 ppb of each of four target gases (DMMP, hydrogen sulfide, nitrogen dioxide and ammonia) within 60 seconds. In Phase II, we propose to expand this detection capability to a total of seven gases, adding volatile organic compounds, chlorine and half-mustard to the set. We then propose ...

This project address the fabrication of solar blind detectors from the MgZnO material system. Both MBE and MOCVD material growth techniques will be used for deposition of the required material layers. Simulation software we be used to aid in the design of the photodetector structure. Devices will be fabricated from the grown structures and their electrical and optical characteristics determined.

DESCRIPTION provided by applicant For this Phase II STTR proposal the investigators plan to develop and commercialize the radiofrequency RF coil technology to make T body MRI possible and to translate this new technology to vastly improve T clinical MRI as well In the Phase I project leading to this proposal all specific aims were accomplished to demonstrate the feasibility of safely an ...

Advanced effective Micro-glider development will be conceived under this Phase I effort.

DESCRIPTION provided by applicant Some of the most significant therapies that treat disease target nucleic acids Drugs that target nucleic acid include cancer drugs antibiotics and antivirals Combined these classes of drugs have annual sales worldwide of $ billion Antibiotics that target nucleic acids account for $ billion of the $ billion of sales annuall for all antibiotics an ...

The technical objective of this proposal is to demonstrate a Quantum Cascade Laser (QCL) emitting in the 3.0-3.5 & #181;m wavelength region, which employs a metamorphic buffer layer (MBL). It is the goal of this program to develop a QCL single-stripe device which will operate in a single, diffraction-limited lobe under room temperature continuous-wave (CW) operation to moderately high (~ 0.5 W) ou ...

DESCRIPTION provided by applicant One of the challenges of research in infectious diseases is to find ways to use the increasing knowledge of the mechanisms underlying disease transformation and progression to develop novel therapeutic strategies for diseases such as increasing menace of bacterial infections Targeting specific RNA such as rRNA which are involved in proliferation and survival ...

DESCRIPTION provided by applicant Seasonal influenza flu virus an NIAID category C priority pathogen causes widespread infection resulting in at least million cases of severe illness and deaths worldwide Young children and elderly or immunocompromised individuals are typically at greater risk of severe illness or death from influenza Newly emerging strains can result ...

DESCRIPTION provided by applicant Heart attacks i e myocardial infarction or MI occur in more than million patients annually Advances in pharmacological therapy have dramatically improved survival following the initial MI Consequently the number of patients with previous MI continues to increase and as a result put in jeopardy millions of patients for development of heart failure I ...

DESCRIPTION provided by applicant Self monitoring has been described as the andquot cornerstone of the behavioral treatment of obesityandquot Consistent self monitoring of energy intake is associated with improved dietary adherence and weight loss and maintenance The problem is that individuals are notoriously bad at self monitoring their intake and suffer from an underreporting bias The s ...