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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Use of Dose Safety Controller (DSC) Artificial Pancreas in Subjects with Hypoglycemia Unawareness

    SBC: DOSE SAFETY INC            Topic: 200

    DESCRIPTION provided by applicant The objective of this project is to demonstrate that the Dose Safety Controller DSC improves the health and lives of persons with Type diabetes T D that have become unaware of hypoglycemia This research aims to show that an artificial pancreas AP device using the DSC will safely andamp effectively control blood glucose for T D patients with hypogly ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Cryopreservation of Engineered Tissue Equivalents

    SBC: TISSUE TESTING TECHNOLOGIES LLC            Topic: 300

    DESCRIPTION provided by applicant In an effort to reduce the use of animals for toxicity testing companies have developed in vitro skin models or equivalents to replace the Draize skin irritation test This development has been further pushed by the European Union regulation that has prohibited the use of animals for collecting toxicological data on cosmetic ingredients that began Supply ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Topical Silver Sulfadiazine Formulations with Improved Efficacy and Toxicity Prof

    SBC: Novion Technologies            Topic: 300

    DESCRIPTION provided by applicant Silver Sulfadiazine SSD is the most widely used topical antimicrobial agent in the world and while effective against a wide variety of pathogens i has been shown to delay wound healing Formulation of SSD into creams and gels with the inclusion of a naturally occurring component additive has been shown to significantly lower the toxicity of the formulation ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Subcutaneous Drug Development for Portal Hypertension Ascites

    SBC: PHARMAIN CORPORATION            Topic: 300

    DESCRIPTION provided by applicant The prevalence of all types of ascites irrespective of the cause is in with of these due to cirrhosis Ascites is treated with a salt restricted diet and pharmacologic therapy using diuretics However in to of patients with ascites the ascites becomes refractory to medical therapy Half of patients who develop refractory ascites due ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. PET Enabled Microspheres for Radioembolization of Liver Tumors

    SBC: XL Sci Tech Inc            Topic: 102

    DESCRIPTION provided by applicant Current radioembolic Y microspheres have been generally recognized as the state of the art for treating primary and metastatic liver tumors However the clinical results vary vastly due to the lack of accurate diagnostic imaging for dose and treatment planning and the lack of image guidance and dose conformation during the administration of Y microsphe ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  6. A 3D particle tracking tool for next generation neuroscience microscopy

    SBC: DRVISION TECHNOLOGIES LLC            Topic: 101

    DESCRIPTION provided by applicant Time lapse D imaging of functional neural networks composed of many neurons connected through a complex web of synapses is a promising approach for gaining in depth understanding of how the central nervous system CNS works Using high speed confocal and fluorescence microscopy D sequences are routinely acquired to elucidate the development of functional ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Direct visualization assay for detection of B. burgdorferi in early Lyme Disease

    SBC: RareCyte, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant Lyme disease a tick borne infection caused by the spirochete Borrelia burgdorferi has expanded to an estimated US cases per year Currently approved tests of immune response are sub optimal and often give negative results early in the disease The research outlined in this application is to develop a diagnostic blood test that directly visualizes B b ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Development of an Advanced In-Vitro Model for Angiogenesis Research and Drug Test

    SBC: Nortis, Inc.            Topic: NHLBI

    DESCRIPTION provided by applicant Abnormal angiogenesis the growth of new blood vessels from existing vasculature plays a central role in more than seventy major health conditions afflicting over one billion people worldwide Uncovering the mechanisms that control angiogenesis promises to fuel the discovery of novel therapies targeting cancer diabetes macular degeneration and others but the ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  9. A Rapid assay for RNA targeted drugs: Instrumentation Supplement

    SBC: NUBAD LLC            Topic: 300

    DESCRIPTION provided by applicant Some of the most significant therapies that treat disease target nucleic acids Drugs that target nucleic acid include cancer drugs antibiotics and antivirals Combined these classes of drugs have annual sales worldwide of $ billion Antibiotics that target nucleic acids account for $ billion of the $ billion of sales annuall for all antibiotics an ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Eco: An Online Virtual World for Secondary School Environmental Literacy and Collaborative Problem Solving

    SBC: STRANGE LOOP GAMES INC.            Topic: N/A

    The project team is developing a prototype of Eco, a multi-player game to prepare high school students to be environmentally literate citizens with 21st century skills. To play the game, students will enter a shared online world featuring a simulated ecosystem of plants and animals. Students will co-create the civilization by measuring, modeling, and analyzing the underlying ecosystem. Students ad ...

    SBIR Phase I 2014 Department of Education
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