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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Next Generation Tools for Onsite Monitoring and Treatment of Drug of Abuse-Dependent Persons
SBC: SensoDX II, LLC Topic: NIDAAbstract Opioid abuse disorder (OAD) affects 2.1 million of Americans annually resulting in overdoses numbering in the tens of thousands and skyrocketing rates of mortality. In addition to its enormous social impact, OAD carries a multi-billion-dollar price tag that includes $78.5 billion, specifically for health care and other costs related to prescription opioid abuse and misuse. Although effect ...
STTR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health -
Resveratrol as a Corneal Pain Therapeutic
SBC: TED'S BRAIN SCIENCE INCORPORATED Topic: NMore thanindividuals undergo laser vision correction surgery each year in the United Statesincluding laser assisted in situ keratomileusisLASIKand photorefractive keratectomyPRKThese procedures damage the nerves in the corneal epithelium causing intense acute pain that most patients rate as greater thanon ascalemany report the pain to beunbearableeven after analgesic treatmentWhile virtually all p ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Identifying hereditary cancer patients in low-resource community cancer settings using an innovative informatics solution
SBC: SGgenomics, Inc. Topic: 101PROJECT SUMMARYHereditary cancer risk assessment in low resource community cancer settings is a signi cant unmet clinical needUnfortunatelymost community cancer clinics do not have adequate access to genetics expertise and patients are not systematically assessed for hereditary riskNew cost e ective and practical approaches are needed to assess and identify patients at risk for hereditary cancer c ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Advance Early Detection of Lupus Nephritis with ClearGold
SBC: CLEARNANO INC Topic: 400SummarySystemic lupus erythematosusSLEor lupus is an autoimmune disease that impacts more thanmillion people worldwideincludingmillion AmericansNearlyof these patients will develop lupus nephritiswhich can cause kidney failureAs a resultits financial burden to individual patient can reach $yearmuch higher than many other diseases because of kidney transplantationAlthough early treatment of lupus n ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Granulocyte/Monocyte Precursors to Treat Neutropenia after Cancer Chemotherapy
SBC: CORD BLOOD PLUS, INC. Topic: 102PROJECT SUMMARY ABSTRACT The objective of this proposal is to move our product forward toward commercialization by improving the quality of life for breast cancer chemotherapy patientsThis will be achieved by the following Specific AimsAimwill optimize differentiation of GMPs and neutrophil lineages in culture in response to G CSFThis will be assessed by flow cytometry to quantify production of ne ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Next generation HDAC inhibitors with superior potency, selectivity, and pharmacokinetic profiles for the treatment of liver ischemia-reperfusion injury
SBC: Lydex Pharmaceuticals LLC Topic: 300Hepatic ischemia reperfusion injuryIRIoccurs in many clinical situationssuch as traumahepatic surgerye gliver resection for tumor treatmentliver donation and transplantationshock and vascular diseasesHepatic I R causes severe liver injury and promotes inflammationleading to liver dysfunctionmultiple organ failure and deathIt also compromises long term outcomes after surgery and traumaCurrentlyno e ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Development of the GlycoFibrotyper for detection of liver fibrosis
SBC: GLYCOPATH INC Topic: 300Increasinglyalterations in N linked glycans have been reported for serum or plasmaor for the most abundant serum glycoproteinimmunoglobulin Gfrom large cohorts of samples representing rheumatoid arthritisdigestive diseasescancer and liver fibrosisIn the case of fibrosistwo tests have identified alterations in Nlinked glycosylation on both total IgG populations and on specific IgG moleculesBoth of ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Carbidopa, an iron chelator and an ABCG2 inducer, for treatment of gouty arthritis
SBC: South Plains Biotechnology, Inc Topic: NIAMSOur goal is to evaluate the efficacy of the FDA approved drug Carbidopa for the treatment of gouty arthritis in mouse modelsCarbidopa is used to treat Parkinson s diseasebut always in combination of L DOPAnever alone by itselfGouty arthritis is caused by deposition of monosodium urateMSUcrystals in jointsinitiating inflammation and arthritisInterestinglygout is not always directly related to incre ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Preclinical studies to validate the efficacy of novel mechanism-of-action small molecule inhibitors to treat Duchenne muscular dystrophy
SBC: RIDGELINE THERAPEUTICS LLC Topic: NIAMSProgressive muscle weakness and degeneration is a hallmark of Duchenne muscular dystrophyDMDIn DMD patientsthe lack of dystrophin reduces muscle fiber structural integritymaking muscles vulnerable to persistent injury and damageRepairing these damaged muscles requires the continual activation of muscle stem cellsmuSCwhich leads to muSC dysfunction and senescenceand ultimately the muscle degenerati ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health -
Development of a Novel Bio-Adhesive Mesh System for Abdominal Hernia Repair
SBC: CIRCA BIOSCIENCE LLC Topic: 300Development of a Novel Bio Adhesive Mesh System for Abdominal Hernia Repair Project Summary Abstract This project proposes the development of a novel mesh adhesive system for abdominal hernia repair utilizing surface modification of polymer surgical mesh to allow for improved tissue fixation with a poloxamine hydrogel adhesiveMore thanmillion Americans undergo hernia repair with surgical mesh each ...
STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health