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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Bioelectrocatalyzed Nitrogen Fixation under Standard Conditions

    SBC: Fulcrum Bioscience, LLC            Topic: A13AT007

    The Haber-Bosch process is the dominant industrial method for nitrogen fixation in the world, with production exceeding 140MM tons in 2009. This process of converting nitrogen and hydrogen to ammonia is one of the great scientific achievements in the modern world. However, Haber-Bosch process is energy intensive requiring pressures >150 bar and temperatures >400 C to achieve 8-15% efficiency. I ...

    STTR Phase II 2014 Department of DefenseArmy
  2. Backbone Degradable Polymer-drug Conjugates for the Treatment of Ovarian Cancer

    SBC: THERATARGET, INC.            Topic: NCI

    DESCRIPTION provided by applicant The purpose of this Phase II STTR project is to develop a polymeric system for the combination delivery of two antineoplastic agents gemcitabine and paclitaxel Based on the successful results of the STTR Phase I award this Phase II proposal details the rationale and research plan for the synthesis and evaluation of in vivo efficacy of two novel macromolecula ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  3. A Rapid assay for RNA targeted drugs: Instrumentation Supplement

    SBC: NUBAD LLC            Topic: 300

    DESCRIPTION provided by applicant Some of the most significant therapies that treat disease target nucleic acids Drugs that target nucleic acid include cancer drugs antibiotics and antivirals Combined these classes of drugs have annual sales worldwide of $ billion Antibiotics that target nucleic acids account for $ billion of the $ billion of sales annuall for all antibiotics an ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Development of Peptide Antibiotic Nucleic Acids

    SBC: NUBAD LLC            Topic: NIAID

    DESCRIPTION provided by applicant One of the challenges of research in infectious diseases is to find ways to use the increasing knowledge of the mechanisms underlying disease transformation and progression to develop novel therapeutic strategies for diseases such as increasing menace of bacterial infections Targeting specific RNA such as rRNA which are involved in proliferation and survival ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Reversal of Myocardial Infarction by Localized Stimulation

    SBC: Micro Vide, LLC            Topic: NHLBI

    DESCRIPTION provided by applicant Heart attacks i e myocardial infarction or MI occur in more than million patients annually Advances in pharmacological therapy have dramatically improved survival following the initial MI Consequently the number of patients with previous MI continues to increase and as a result put in jeopardy millions of patients for development of heart failure I ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Assessing the Bite Counter as a Tool for Food Intake Monitoring: Phase II

    SBC: BITE TECHNOLOGIES, LLC            Topic: 300

    DESCRIPTION provided by applicant Self monitoring has been described as the andquot cornerstone of the behavioral treatment of obesityandquot Consistent self monitoring of energy intake is associated with improved dietary adherence and weight loss and maintenance The problem is that individuals are notoriously bad at self monitoring their intake and suffer from an underreporting bias The s ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  7. A Multiscale Modeling and Simulation Framework for Predicting After-Burning Effects from Non-Ideal Explosives

    SBC: REACTION ENGINEERING INTERNATIONAL            Topic: N10AT002

    The objective of the proposed Phase II STTR effort is to develop a validated computational tool to predict the afterburning of non-ideal munitions containing metal and hydrocarbon fuels. The activities outlined devise a well-coordinated collaboration among researchers from Reaction Engineering International (REI) and the State University of New York at Buffalo (UB). The activities proposed will bu ...

    STTR Phase II 2011 Department of DefenseNavy
  8. Solvothermal growth of low-defect-density gallium nitride substrates

    SBC: ADVANCED PHOTONIC CRYSTALS, LLC            Topic: AF10BT28

    ABSTRACT: This Small Business Technology Transfer Phase I project will address the problem of obtaining low-defect-density gallium nitride single crystals for substrates to enable low-defect, high-performance epitaxial growth. Gallium nitride is a very promising material for numerous applications including surface acoustic wave devices, high-powered LEDs, UV diode lasers and high-powered RF devic ...

    STTR Phase I 2011 Department of DefenseAir Force
  9. Novel Biomass Conversion Process for Production of Butylenes

    SBC: Technology Holding, LLC            Topic: N10BT047

    The United States is currently faced with unprecedented energy challenge. Petroleum prices have skyrocketed due to rising competition for energy resources from emerging economies. There is a significant need for processes that can produce hydrocarbons from renewable resources rather than petroleum. The use of renewable resources ensures a long-term supply of hydrocarbons, even after easily extract ...

    STTR Phase I 2011 Department of DefenseNavy
  10. Backbone Degradable Polymer-drug Conjugates for the Treatment of Ovarian Cancer

    SBC: THERATARGET, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): This Phase I proposal details the rationale and the research plan for the synthesis and characterization of targeted, backbone degradable, long-circulating polymer conjugates containing two anticancer drugs per macromolecule. The polymeric carrier will be composed of alternating N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer segments (blocks) and enzymatica ...

    STTR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health
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