Award Data

The project will create an affordable system to monitor adolescent athletes in contact sports to identify individuals at risk for traumatic brain injury from continual sub-concussive impacts. The need is to reduce the risk of long term brain injury by providing tools to tell when it's risky/safe to play and find areas where strength training and technique may reduce risk on an individual level. Th ...

Innovative Design Labs (IDL), in collaboration with the Rehabilitation Institute of Chicago (RIC), proposes to create a system for the sensing and control of stand-to-sit motions of a wearable bionics suit. Recent research found that 3.86 million Americans require wheelchairs and the number has been increasing annually by an average annual rate of 5.9% a year. While wheelchairs provide freedom all ...

DESCRIPTION provided by applicant In an effort to reduce the use of animals for toxicity testing companies have developed in vitro skin models or equivalents to replace the Draize skin irritation test This development has been further pushed by the European Union regulation that has prohibited the use of animals for collecting toxicological data on cosmetic ingredients that began Supply ...

DESCRIPTION provided by applicant For this Phase II STTR proposal the investigators plan to develop and commercialize the radiofrequency RF coil technology to make T body MRI possible and to translate this new technology to vastly improve T clinical MRI as well In the Phase I project leading to this proposal all specific aims were accomplished to demonstrate the feasibility of safely an ...

DESCRIPTION provided by applicant This proposed project aims to develop an advanced telemetry system for body worn continuous glucose sensors using a new radio based on ultra wideband impulse radio technology The proposed radio features ultra low power and multiple layers of security including distance bounding for secure reliable and low cost body area sensor networks There has been an inc ...

DESCRIPTION provided by applicant Urinary tract infections UTIs caused by extraintestinal pathogenic E coli ExPEC account for nearly million emergency room visits and hospitalizations per year for women in the U S alone Approximately half of all women will experience a symptomatic UTI in their lifetime and will experience a recurrence within to months While several ...

DESCRIPTION provided by applicant The purpose of this Phase II STTR project is to develop a polymeric system for the combination delivery of two antineoplastic agents gemcitabine and paclitaxel Based on the successful results of the STTR Phase I award this Phase II proposal details the rationale and research plan for the synthesis and evaluation of in vivo efficacy of two novel macromolecula ...

DESCRIPTION provided by applicant In spite of remarkable progress in management of rheumatoid arthritis RA a devastating autoimmune disease that affects million Americans causing chronic inflammation of joints and surrounding tissues the gap of unmet needs in this therapeutic field remains wide open First of all almost of the patients do not respond adequately to the most advanced ...

DESCRIPTION provided by applicant Large numbers of American workers are exposed to high noise environments during their work days Hearing loss from noise exposure is the most common occupational injury for American workers Disposable viscoelastic foam earplugs are widely used to provide personal hearing protection The ability of these foams to attenuate noise has essentially plateaued at the ...

DESCRIPTION provided by applicant Koronis Biomedical Technology Corporation KBT proposes to develop and evaluate a miniature ultra low power pulse oximeter for long term wearable monitoring There continues to be a clinical need for an unobtrusive pulse oximeter sensor that is small and can be worn comfortably for extended periods of time without battery change or recharge KBT will use eye s ...