Award Data

The area of thin film growth has progressed rapidly, producing many high performance new materials which require accuracy of their atomic composition to perform as expected. Any method to provide real time in situ information about the elemental composition of the growing surface is highly valuable for these new, complicated materials. Utilizing a new instrument design, the Phase I project team ...

The objective of this phase II STTR program is twofold: (1) to design, prototype, and commercialize differential on-wafer probes for characterizing devices in the 140220 GHz and 220320 GHz bands, and (2) to engineer the geometry and material of the micromachined probe tip to enable robust, consistent, and low-resistance electrical contact to devices with various contact pad metallizations, includi ...

DESCRIPTION provided by applicant Obstructive sleep disordered breathing OSDB is common in both children and adults and is recognized as having substantial health related consequences at all ages Laboratory polysomnography PSG is the gold standard for diagnosing OSDB but the procedure is not without problems Polysomnographic studies are complex invasive expensive not universally avail ...

Skin infections caused by bacteria represent a significant risk to wounded soldiers. The most common source of bacterial infection is found in the fabrics of clothing, boots, and gear worn by the warfighter. Reducing the risk of infection for soldiers by treating the source fabrics will lead to positive outcome and support medically-related activities in non-sterile environments encountered by t ...

The low density of magnesium makes it of interest for the development of advanced materials having high specific strength and stiffness. Current Mg applications, however, are limited by the performance and cost/quality relationships of existing Mg-alloy systems. One approach to obtain improved Mg alloys is through the development of new alloys and/or Mg-based composite materials that are enabled t ...

Antimicrobial treatments have been incorporated in a number of textile products used by the U.S. Army to control odor and reduce skin irritation, thus improving the quality of life for the warfighters. Current textile treatment using chemically-derived antimicrobials such as metals (silver- and copper-based compounds), polyphenols, halamines and quaternary ammonium compounds can effectively kill o ...

DESCRIPTION provided by applicant Some of the most significant therapies that treat disease target nucleic acids Drugs that target nucleic acid include cancer drugs antibiotics and antivirals Combined these classes of drugs have annual sales worldwide of $ billion Antibiotics that target nucleic acids account for $ billion of the $ billion of sales annuall for all antibiotics an ...

DESCRIPTION provided by applicant One of the challenges of research in infectious diseases is to find ways to use the increasing knowledge of the mechanisms underlying disease transformation and progression to develop novel therapeutic strategies for diseases such as increasing menace of bacterial infections Targeting specific RNA such as rRNA which are involved in proliferation and survival ...

DESCRIPTION provided by applicant Advances in DNA sequencing technology have now made it practical and affordable to generate datasets containing millions of genetic attributes that can be tested for association with disease susceptibility The computational complexity of searching for genetic interactions over such high dimensional datasets imposes great challenges for genome wide associatio ...

DESCRIPTION provided by applicant Heart attacks i e myocardial infarction or MI occur in more than million patients annually Advances in pharmacological therapy have dramatically improved survival following the initial MI Consequently the number of patients with previous MI continues to increase and as a result put in jeopardy millions of patients for development of heart failure I ...