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DESCRIPTION provided by applicant Mass spectrometry based proteomics is an emerging technology that has seen possible applications everywhere The technique can potentially use one drop of our blood to reveal onset and progress of diseases Current Randamp D using plasma serum proteome sample sets however is severely limited by the high complexity and dynamic range of protein concentrations ...

DESCRIPTION provided by applicant Metastasis or dissemination of primary tumor cells is the major cause of mortality in cancer patients Circulating tumor cells CTCs in the bloodstream are key players in the establishment of metastatic tumors Recent studies demonstrated that the number of CTCs present in patient blood directly correlate with cancer progression recurrence and survival rate ...

This DOD Phase I STTR program would develop III-V multijunction based solar cells, using Virginia Tech"s InGaP/GaAs/InGaAs multijunction cells technique in combination with NanoSonic"s pioneering Hybridsil antireflection copolymer nanocomposite materials, which afford high levels of antireflection, temperature and abrasion resistance, impact durability and hydrophobicity (self cleaning). Such an a ...

Most of current available methods for prediction of fatigue failure -such as cumulative damage models, cyclic plastic energy hypothesis, crack propagation rate models, and empirically-derived relationships -are based on empirical relations and their application requires many unknown parameters that must be experimentally determined or calibrated for specific locations/critical areas. Also, the afo ...

DESCRIPTION provided by applicant The measurement monitoring and use of bioelectric signals has evolved from the measurement of the electrical activity of the heart to encompass tissues ranging from cardiac skeletal and smooth muscles to brain and peripheral nerve tissues Together with this development has been the evolution of specialized equipment to capture and interpret these minute sig ...

DESCRIPTION provided by applicant Obstructive sleep disordered breathing OSDB is common in both children and adults and is recognized as having substantial health related consequences at all ages Laboratory polysomnography PSG is the gold standard for diagnosing OSDB but the procedure is not without problems Polysomnographic studies are complex invasive expensive not universally avail ...

The major objectives of the Phase I effort will be focused on CDC higher pressure combustion (using natural gas or hydrogen-GREEN MANUFACTURING) driven powder compaction fabrication of select alloys for Microwave Tube Related Component end uses for NAVY using powders of varying sizes and vacuum-grade purity such as Cupro-Nickel, Stainless Steels (e.g., 316 LN, Custom 465 high strength version), Mo ...

A database-driven approach is needed which characterizes the failure modes of the mechanical components of submarine systems under extreme loadings. Such an application must provide automation of the component shock qualification process through an automated capability while providing component-level qualification based upon similarity of components and failure modes. Certification of shock worthi ...

The Fixed Submarine Broadcasting System is a low frequency (LF) and very low frequency (VLF) communication system that provides independent and survivable connectivity to the United States Navy nuclear submarine force. The Navy operates six high powered VLF and seven LF transmitter facilities at different locations around the world. These outdoor transmission antennas operate at extremely high pow ...

Naval vessels which regularly encounter sub-freezing environments experience superstructure ice accumulation which has negative effects on seaworthiness, deck safety, and ship system performance. In order to mitigate risks to mission success, this ice is currently removed with tools and de-icing solvents through a hazardous manual process with risk of damaging ship components. Ideally, these de-ic ...