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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. NOVEL THERAPEUTIC APPROACH TO PSORIASIS

    SBC: BETHESDA PHARMACEUTICALS, INC.            Topic: N/A

    DESCRIPTION (Applicant's abstract): Psoriasis is a common, inflammatory disease of the skin characterized by hyper-proliferation of keratinocytes. A variety of antipsoriatic therapies are available, however, due to problems with side effects and variability in clinical response, intense clinical and commercial interest remains in the development of new treatments. Thiaz ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  2. Biomaterials for Orbit Reconstruction

    SBC: BIOMIMESYS, INC.            Topic: N/A

    DESCRIPTION (Verbatim from Applicant): We will develop biomimetic materials for repair and orthoplasty of the orbit and surrounding bony structures. These scaffolds will incorporate a cell binding peptide related to collagen which will allow them to serve as collagen-like anchorages for cells. These Collagen Surrogate Matrices (CSM) will facilitate haptotactic migrati ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  3. Hydroxyl radical mapping of protein interfaces

    SBC: EXSAR CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): Identifying amino acid residues of a protein that form the binding site for a drug, or that are present at the interface in a protein-protein complex are difficult to identify from the crystal structures of the individual partner proteins. Carta Proteomics is committed to the premise that monitoring isotope exchange in ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  4. Parametric models for survival analysis

    SBC: EPICENTER SOFTWARE            Topic: N/A

    DESCRIPTION (provided by applicant): The most commonly used statistical methods for the design and analysis of cancer clinical trials today rely heavily on the idea of proportional hazards or its generalizations; i.e., that the important differences between treatments are reflected in the differences between failure rates. Implicit in the use of these methods is the assumptio ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  5. In Silico Prediction of Metabolic Gene Expression Patter

    SBC: GENOMATICA, INC.            Topic: N/A

    The recent explosion of biological information now available to researchers at all levels of biological investigation has resulted in-part from high-throughput technologies to sequence genes and proteins, and to determine their expression patterns, in an attempt to capture the algorithmic complexity of biological functions. Collectively, this data has begun to enable the study of cells as living s ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  6. Combinatorial Carbohydrate Libraries for Drug Discovery

    SBC: IBIS BIOSCIENCES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Development of new antimicrobial compounds is urgently needed as bacteria evolve resistance to the antibiotics of last resort. The long-term objective of this proposal is to identify new carbohydrate-based compounds that bind to the small ribosomal subunit and specifically alter bacterial translation. Five hundred new a ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  7. Retroviral Vectors for Cancer Gene Therapy

    SBC: INTRAGENE SCIENCES, INC.            Topic: N/A

    Many strategies for gene therapy of solid tumors such as prostate cancer have involved the use of Moloney murine leukemia (MLV)-based retroviral vectors, but gene transfer with standard replication-defective MLV vectors has not been efficient due to their low titers and limited diffusion into the tumor. Gene transfer using replication-competent retroviral vectors would be more efficient, as each ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  8. NOVEL ANTI-PAIN MEDICATIONS FOR CANCER

    SBC: IRISYS RESEARCH AND DEVELOPMENT            Topic: N/A

    DESCRIPTION (provided by applicant): The chemical synthesis and biological evaluation of novel, highly potent agents for the treatment of both severe acute and chronic pain associated with cancer and other diseases that has minimal side effects such as addiction liability, imniunosuppression and respiratory depression is very urgent. For "proof of princip ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  9. Identification of a Neuronal Immunosuppressive Protein

    SBC: LAYTON BIOSCIENCE, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Development of Ntera2/D1 neurons as an alternative to embryonic neurons for transplantation therapy to ameliorate neurological deficits, currently in a Phase I trial for stroke symptoms, led to our discovery of a 40-60 kDA anionic protein with an isoelectric point of 4.8 expressed by these neurons that inhibits T-lymphocyte activa ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  10. AIRWAY PERFUSION ASSISTED LIQUID VENTILATOR

    SBC: MALLARD MEDICAL CO., INC.            Topic: N/A

    DESCRIPTION (provided by applicant): We have developed and patented (U.S. Pat No. 5,706,830) a new type of closed circuit perfluorocarbon (PFC) liquid ventilator with enhanced capabilities for gas exchange and exudates clearance from the lungs. This system has potential application to rescue of patients in acute respiratory failure and treatment of cystic fibrosis. ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
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