You are here
Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
-
RNA Detection as an Improved Diagnostic Assay for Human Leptospirosis
SBC: L2 DIAGNOSTICS LLC Topic: NIAIDDESCRIPTION provided by applicant Leptospirosis a zoonotic disease is an important public health problem worldwide It is caused by spirochete bacteria belonging to nine species and more than serovars of the genus Leptospira In the US there is increasing awareness of the importance of leptospirosis as the cause of disease among inner city populations military personnel and individuals ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
A Multivalent Lyme Disease Vaccine Targeting Tick-Host-Pathogen Interactions
SBC: L2 DIAGNOSTICS LLC Topic: NIAIDDESCRIPTION provided by applicant This proposal seeks to develop a novel vaccine against Lyme disease by targeting Ixodes scapularis proteins critical for Borrelia burgdorferi transmission from the tick to mammalian host Earlier work has identified four tick proteins Salp TRE tHRF and TSLPI that facilitate different steps of spirochete transmission and immunity against these protein ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Development of Peptide Antibiotic Nucleic Acids
SBC: NUBAD LLC Topic: NIAIDDESCRIPTION provided by applicant One of the challenges of research in infectious diseases is to find ways to use the increasing knowledge of the mechanisms underlying disease transformation and progression to develop novel therapeutic strategies for diseases such as increasing menace of bacterial infections Targeting specific RNA such as rRNA which are involved in proliferation and survival ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Targeting STT3A and STT3B to Block Flavivirus Replication
SBC: New England Discovery Partners, LLC Topic: NIAIDAbstractMosquito borne flaviviruses cause disease worldwidewith members such as dengue virusDENVZika virusZIKVand west nile virusWNVinfecting more thanmillion individuals annuallyThe availability of small molecule antivirals that reduce flavivirus infection therefore could have an immediate and substantial impact on public health programs that seek to improve outcomes for populations infected with ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Cell-penetrating antimicrobial therapeutics for treatment of complicated skin and soft tissue infections
SBC: TSRL, INC. Topic: NIAIDAbstract In the United Statesskin and soft tissue infectionsSSTIsare one of the most common indications for antibiotic treatmentrepresentingof hospital admissions andmillion doctor visits a yearSSTIs range from selflimiting furuncles and cellulitis to life threatening sepsis and tissue necrosisRecent studies suggest more thanof all SSTIs were caused by staphylococcal or streptococcal speciesin par ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Validation of a Diagnostic Test for Borrelia miyamotoi
SBC: L2 DIAGNOSTICS LLC Topic: NIAIDABSTRACT Borrelia miyamotoi is a tick transmitted spirochete recently shown to cause infection and disease in the United StatesEurope and AsiaA member of the relapsing fever group of Borreliathis pathogen has been proven to cause most commonly a nonspecificflu like illness with feverfatiguemyalgiaand headacheDisease can be particularly severe and involve the central nervous system in immunocomprom ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
A novel approach to treat non alcoholic steatohepatitis NASH
SBC: MITOTHERAPEUTIX, LLC Topic: 300Abstract The Specific Aim of this Phase I STTR proposal is to test the feasibility of treating non alcohol steatohepatitis NASH by increasing mitochondrial metabolism which is the main pathway for lipid catabolism in the liver NASH is a stage of non alcohol fatty liver disease NAFLD that has progressed to a pathological state NASH can lead to cirrhosis leading to liver failure or hepatocel ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Fc folate Conjugate for the Treatment of Triple Negative Breast Cancer
SBC: NeuLink Inc. Topic: 100Abstract According to the American Cancer Society in women in the U S will develop breast cancer at some point in their life and of these women will have triple negative breast cancer TNBC an aggressive subtype of breast cancer that lacks the three receptors ER PR HER that current drug treatment targets tamoxifen Herceptin Because of its aggressive nature and lack of effec ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Development of MTX for the Treatment of KRAS Mutant Colorectal Cancer
SBC: Mekanistic Therapeutics, LLC Topic: NCIPROJECT SUMMARY Mekanistic Therapeutics seeks to design discover and develop anti cancer agents that selectively inhibit multiple oncogenic pathways Its lead agent MTX was discovered in collaboration with the Leopold laboratory at University of Michigan MTX is a novel kinase inhibitor showing early promise for its therapeutic potential against solid cancers refractory to current treatm ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health -
Ground state rabbit pluripotent stem cells
SBC: ATGC Inc. Topic: ODAbstract To evaluate the therapeutic applications of stem cells it is essential to develop translational research using several animal species Rabbit is a useful model for biomedical research It has been used to study a number of human diseases Compared to mice rabbits have a more similar embryology and stem cell biology to those of humans an adult body size comparable to human infants that ...
STTR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health