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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A simple assay system for rapid detection of circulating tumor cells

    SBC: TELOVISION, LLC            Topic: NCI

    DESCRIPTION provided by applicant Metastasis or dissemination of primary tumor cells is the major cause of mortality in cancer patients Circulating tumor cells CTCs in the bloodstream are key players in the establishment of metastatic tumors Recent studies demonstrated that the number of CTCs present in patient blood directly correlate with cancer progression recurrence and survival rate ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Development of Peptide Antibiotic Nucleic Acids

    SBC: NUBAD LLC            Topic: NIAID

    DESCRIPTION provided by applicant One of the challenges of research in infectious diseases is to find ways to use the increasing knowledge of the mechanisms underlying disease transformation and progression to develop novel therapeutic strategies for diseases such as increasing menace of bacterial infections Targeting specific RNA such as rRNA which are involved in proliferation and survival ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Metal ion-functionalized soluble nanopolymers: A new analytical platform for plas

    SBC: TYMORA ANALYTICAL OPERATIONS LLC            Topic: 300

    DESCRIPTION provided by applicant Mass spectrometry based proteomics is an emerging technology that has seen possible applications everywhere The technique can potentially use one drop of our blood to reveal onset and progress of diseases Current Randamp D using plasma serum proteome sample sets however is severely limited by the high complexity and dynamic range of protein concentrations ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Universal amplifier system for high-fidelity multi-modal biosignal recordings

    SBC: REFER2INPUT, LLC            Topic: 213

    DESCRIPTION provided by applicant The measurement monitoring and use of bioelectric signals has evolved from the measurement of the electrical activity of the heart to encompass tissues ranging from cardiac skeletal and smooth muscles to brain and peripheral nerve tissues Together with this development has been the evolution of specialized equipment to capture and interpret these minute sig ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Novel treatment of posttraumatic stress disorder

    SBC: ANAGIN            Topic: 101

    DESCRIPTION provided by applicant The present application andquot Novel Treatment for Posttraumatic Stress Disorderandquot addresses the critical need for efficacious treatments for posttraumatic stress disorder PTSD A key neural signaling cascade activated by a trauma experience is initiated by the excitatory neurotransmitter glutamate Activation of the NMDA receptor a glutamate receptor ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Development of a Novel ELISA Kit for Screening Potential JAK3 Inhibitors

    SBC: Twenty First Century Therapeutics, Inc.            Topic: 300

    DESCRIPTION provided by applicant Janus kinase JAK is an intracellular kinase involved in cytokine and antibody receptor signaling it is frequently over activated during the course of inflammatory autoimmune diseases Therefore suitable JAK inhibitors that modulate the overexpression of JAK may be potential agents for treating autoimmune diseases Logically it is of significant import ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Nucleoside Phosphonate Analogs for the Treatment of Adenoviral Infection

    SBC: TSRL, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Adenovirus can be a significant health risk for immune compromised patients both adult and pediatric patients In pediatric patients in particular complications associated with adenoviral infection include pneumonia urinary infections and hepatitis In the military setting adenoviruses are endemic in Department of Defense basic recruit training installation ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Gamma-Ray Imaging Spectrometers for Nuclear Materials Accounting and Control

    SBC: H3D INC            Topic: 19c

    The nuclear security and safeguards community does not have an effective tool to track the location and quantities of radioactive material within facilities. This effort will result in a sensor that can provide precise locations and quantities of radioisotopes in complex measurement environments. It is in the national interest to develop the best possible tools to monitor all aspects of the domes ...

    SBIR Phase I 2014 Department of Energy
  9. Printed Electronic Film Construction for SSL

    SBC: Innotec, Corp.            Topic: 03a

    High material costs and high manufacturing costs have been identified as one of the critical barriers that are slowing the adoption of Solid State Lighting. A 2012 Department of Energy report estimated that Solid-State Lighting has the potential to reduce electric energy consumed by lighting from 694TWh in 2010 to 375TWh in 2030. Overcoming the materials and manufacturing cost barriers in order t ...

    SBIR Phase I 2014 Department of Energy
  10. Tailoring Cementitious Materials Towards Value-Added Use of Large CO2 Volumes

    SBC: METNA CO            Topic: 13c

    Carbon capture and storage is generally considered as a crucial component of any U.S. strategy for addressing the climate change problem. Carbon dioxide can be stored underground in geologic formations, or permanently bound into some abundant minerals via carbonation reactions. These options have been subject of significant research and development efforts. The proposed project employs the advance ...

    SBIR Phase I 2014 Department of Energy
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