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DESCRIPTION provided by applicant Metastasis or dissemination of primary tumor cells is the major cause of mortality in cancer patients Circulating tumor cells CTCs in the bloodstream are key players in the establishment of metastatic tumors Recent studies demonstrated that the number of CTCs present in patient blood directly correlate with cancer progression recurrence and survival rate ...

DESCRIPTION provided by applicant One of the challenges of research in infectious diseases is to find ways to use the increasing knowledge of the mechanisms underlying disease transformation and progression to develop novel therapeutic strategies for diseases such as increasing menace of bacterial infections Targeting specific RNA such as rRNA which are involved in proliferation and survival ...

DESCRIPTION provided by applicant Mass spectrometry based proteomics is an emerging technology that has seen possible applications everywhere The technique can potentially use one drop of our blood to reveal onset and progress of diseases Current Randamp D using plasma serum proteome sample sets however is severely limited by the high complexity and dynamic range of protein concentrations ...

DESCRIPTION provided by applicant The measurement monitoring and use of bioelectric signals has evolved from the measurement of the electrical activity of the heart to encompass tissues ranging from cardiac skeletal and smooth muscles to brain and peripheral nerve tissues Together with this development has been the evolution of specialized equipment to capture and interpret these minute sig ...

A novel and new method of measuring the far-field noise of a helicopter is proposed by the Delta Group International/University of Maryland team that uses a hot-air-balloon as the measurement platform. The method meets the Army STTR objectives of being capable of measuring helicopter noise above and near the tip-path-plane of the helicopter without measurable ground reflections. The new method i ...

This STTR project seeks to overcome the performance limitations of experimental sulfur tolerant SOFC materials by combining two elements of efficient SOFC design: 1) micro-tubular arrays (OD

Access to clean water is a global problem that has led to the development of multiple desalination techniques. All techniques strive to reduce the cost of desalinating water to provide clean water in a cost effective manner. Capacitive deionization (CDI) is a new technique that can reduce the cost of ownership by ~85% compared with reverse osmosis for brackish water. This project will further im ...

In order to dramatically reduce CO2 emissions from coal-fired power plants, and mitigate their impact on global climate change, DOE has called for technologies that can capture at least 90% of CO2 emissions from an existing coal-fired power plant with no more than a 35% increase in the cost of electricity (COE). One process design approach with the potential to achieve these goals is through the u ...

The Department of Defense is concerned with circadian rhythm misalignments as they are known to affect judgment, psychomotor skills, and can lead to Post-Traumatic Stress Disorder (PTSD). At present, there is no comprehensive unobtrusive and easy-to-use solution that measures the circadian misalignment and automatically administers the appropriate therapy for realignment of circadian rhythm. Intel ...

In this STTR program, technology created at the University of California at Santa Barbara (UCSB) to fabricate silicon photonics based integrated laser devices, including wafer bonded gain elements, will be utilized to develop ultra-coherent integrated laser devices that are widely tunable. Novel laser designs developed by Morton Photonics, taking advantage of ultra-low loss microresonator based f ...