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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Novel fetal heart monitor technology

    SBC: Bioconnexions, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Significant progress has been made in the science of electrocardiography since 1938. Heart rate and biophysical profiles are routinely derived from multi-lead electrocardiograms (ECGs) in animals and humans after birth. In contrast, only limited heart monitoring technologies exist for the fetus. Moreover, available technology fails to satisfy many existing need ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  2. Spinal Fusion Using Adipose Derived Adult Stem Cells

    SBC: Cognate Therapeutics, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Back pain afflicts over 75% of Americans during their lifetime and 2% of the American work force suffers a back injury on the job each year. Spinal fusion is the orthopedic procedure routinely used to treat back pain in patients suffering from degenerative disc disease, spinal stenosis, scoliosis, and spinal fracture; however, procedure failure rates range betw ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  3. Extended DNA amplification with thermostable chaperons

    SBC: FIDELITY SYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this project is to develop a general method of improving the stability and durability of enzymes used in DNA and RNA amplification, sequencing, restriction analysis and ligation. The enzymes to be improved include DNA polymerases, topoisomerases, reverse transcriptases and ligases. In the event this goal can be achieved, broad impacts may result in ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  4. Property Measurment and Improved Strength of Duplex Sic/Sic Ceramic Composites for Fast Reactor Fuel Cladding

    SBC: Gamma Engineering Corporation            Topic: 24b

    78329 Generation IV advanced reactors [such as the gas cooled fast reactor (GFR) and the Lead Cooled Reactor (LFR)], selected for development by the Gen IV International Forum, require core outlet temperatures up to 900¿C. Most metals, including refractory alloys, loose much of their strength at these temperatures, and cannot survive core overheating accidents should they occur. Monolithic cera ...

    STTR Phase I 2005 Department of Energy
  5. Restoration of vestibular hair cells induced by AdMath1

    SBC: GENVEC, INC.            Topic: N/A

    Loss of vestibular hair cells can occur due to a variety of disorders and results in dysfunction of the vestibulo-occular reflex and loss of balance. Bilateral vestibular hypofunction due to aminoglycoside ototoxicity and other means is a devastating and currently untreatable chronic disorder because loss of vestibular hair cells is permanent. To date there is no prosthetic device such as a hearin ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  6. Feasibility study of a double fiber bundle dialyzer

    SBC: MIRIMEDICAL, LLC.            Topic: N/A

    DESCRIPTION (provided by applicant): Efficiency of hemodialysis is currently limited by dialyzer technology. Although new membranes with large surface areas have been developed, the increase in delivered treatment is only marginal. Double dialyzer therapies have been shown to be superior to standard high efficiency/ high flux dialysis treatments; however implementation of double dialyzer therapi ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  7. Diffraction Enhanced Imaging Laboratory Research Machine

    SBC: Nesch, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Diffraction enhanced imaging (DEI) is a novel approach to X-ray imaging that has the potential to revolutionize X-ray medical imaging, because of its greater contrast at lower delivered X-ray doses than conventional radiography. DEI relies on measuring tiny angular deflections of a collimated X-ray beam as it passes through the object (patient) in acquiring the ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  8. Assessment of Altered Function in Diabetic Bladder

    SBC: Neurotron, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Diabetic bladder dysfunction (DBD) or diabetic cystopathy is one of the most common and debilitating complications of diabetes mellitus (DM) affecting well over 50% of the patients with either type I or type II diabetes. DBD could affect both the filling and voiding function of the bladder leading to urinary incontinence, poor emptying, high post void residual ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  9. Therapeutic Strategy for Recurrent Spontaneous Abortion

    SBC: Nora, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Recurrent spontaneous abortion (RSA) is a serious medical condition that affects approximately 1-3% of reproductive age women. At present, there is no FDA approved treatment for RSA. We hypothesize that failure to suppress Th1 cytokine production early in pregnancy is a major cause of RSA. We hypothesize that recombinant human granulocyte colony stimulating fa ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  10. Development of VPL Vaccine for RSV

    SBC: SIGMOVIR BIOSYSTEMS, INC.            Topic: NIAID

    Project Summary Human respiratory syncytial virus (RSV) is recognized as the single most important viral cause of acute respiratory disease in infants and young children worldwide. Elderly populations and immunocompromised individuals are also at significant risk for serious RSV disease. Despite this very substantial disease burden imposed by RSV worldwide, there are no vaccines available. Severa ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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