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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Metal ion-functionalized soluble nanopolymers: A new analytical platform for plas

    SBC: Tymora Analytical Operations, LLC            Topic: 300

    DESCRIPTION provided by applicant Mass spectrometry based proteomics is an emerging technology that has seen possible applications everywhere The technique can potentially use one drop of our blood to reveal onset and progress of diseases Current Randamp D using plasma serum proteome sample sets however is severely limited by the high complexity and dynamic range of protein concentrations ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. A simple assay system for rapid detection of circulating tumor cells

    SBC: TELOVISION, LLC            Topic: NCI

    DESCRIPTION provided by applicant Metastasis or dissemination of primary tumor cells is the major cause of mortality in cancer patients Circulating tumor cells CTCs in the bloodstream are key players in the establishment of metastatic tumors Recent studies demonstrated that the number of CTCs present in patient blood directly correlate with cancer progression recurrence and survival rate ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Coupled Multi-physics Analysis and Design Optimization of nozzles (COMANDO)

    SBC: INTELLIGENT AUTOMATION, INC.            Topic: N14AT005

    The US Navy faces daunting energy challenges that will further increase in severity, given the ever-increasing global demand for energy, diminishing energy supplies and demand for enhanced environmental stewardship. Navys environment foot print consists of both emissions and noise generated every day around the world. Additionally, noise is an important issue for the Navy due to the adverse effect ...

    STTR Phase I 2014 Department of DefenseNavy
  4. Universal amplifier system for high-fidelity multi-modal biosignal recordings

    SBC: REFER2INPUT, LLC            Topic: 213

    DESCRIPTION provided by applicant The measurement monitoring and use of bioelectric signals has evolved from the measurement of the electrical activity of the heart to encompass tissues ranging from cardiac skeletal and smooth muscles to brain and peripheral nerve tissues Together with this development has been the evolution of specialized equipment to capture and interpret these minute sig ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Wideband RF Photonic Link with Real-Time Digital Post Processing

    SBC: Pharad, LLC            Topic: N14AT023

    Pharad is teaming with the Applied Physics Laboratory of The Johns Hopkins University to propose and investigate the feasibility of wideband (VHF to SHF) RF-to-digital photonic link architectures with real-time digital signal processing (DSP) that can meet the stringent performance metrics of military systems. The key requirements for our wideband DSP linearized RF-to-digital photonic link include ...

    STTR Phase I 2014 Department of DefenseNavy
  6. Plasma Electrolytic Diffusion Treatments for Reduced Electrochemical Current Density in Aircraft Structural Fasteners

    SBC: IBC Materials & Technologies, LLC            Topic: N14AT014

    Modern aircraft make extensive use of fasteners made of steel, titanium, nickel and other alloys mated with aluminum and composite airframe materials. This coupling of dissimilar materials yields galvanic corrosion issues, which degrades mechanical integrity, is costly to inspect, and poses a safety and reliability risk. Traditional design approaches of corrosion rate predictions based on open cir ...

    STTR Phase I 2014 Department of DefenseNavy
  7. Development of Peptide Antibiotic Nucleic Acids

    SBC: NUBAD, LLC            Topic: NIAID

    DESCRIPTION provided by applicant One of the challenges of research in infectious diseases is to find ways to use the increasing knowledge of the mechanisms underlying disease transformation and progression to develop novel therapeutic strategies for diseases such as increasing menace of bacterial infections Targeting specific RNA such as rRNA which are involved in proliferation and survival ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Next Generation Semiconductor-Based Radiation Detectors Using Cadmium Magnesium Telluride

    SBC: BRIMROSE TECHNOLOGY CORPORATION            Topic: 23c

    At present, CdZnTe is considered the material of choice for efficient, room temperature gamma-radiation detection systems used for the detection and identification of radionuclides. Despite the advances in CdZnTe materials technology during the last decade, the major impediments in the progress of - ray detection technology are the low yield of device quality materials and detectors, and the limit ...

    STTR Phase I 2014 Department of Energy
  9. Development of VPL Vaccine for RSV

    SBC: SIGMOVIR BIOSYSTEMS, INC.            Topic: NIAID

    Project Summary Human respiratory syncytial virus (RSV) is recognized as the single most important viral cause of acute respiratory disease in infants and young children worldwide. Elderly populations and immunocompromised individuals are also at significant risk for serious RSV disease. Despite this very substantial disease burden imposed by RSV worldwide, there are no vaccines available. Severa ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Non-ATP competitive inhibitors of cyclin dependent kinases as cancer therapeutics

    SBC: PPI PHARMACEUTICALS, LLC            Topic: NCI

    DESCRIPTION (provided by applicant): As cancer is one of the leading causes of death in the United States with some sub-types remaining essentially untreatable, expansion of available drug targets will provide significant new options for the development ofmore effective antineoplastic agents. The major goal of this project is to apply a unique drug discovery strategy to cancer drug development. Th ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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