Award Data

MapReduce is a very popular data analytic framework that is widely used in both industry and scientific research. Despite the popularity of MapReduce, there are several obstacles to applying it for developing some commercial and scientific data analysis applications. The project will develop a Native data FOrmat MapREDuce-like framework, iNFORMER, based on OSUs SciMate architecture. The framework ...

For advanced gas turbines where turbine inlet temperature reaches 2650F and beyond, the current state-of-the-art thermal barrier coating (TBC) systems are not adequate to provide the needed protection for the metallic components of the turbine engine. Thus there is a need to develop new chemistries and architectures for TBC systems (both bond coats and top TBCs) with enhanced durability. For the ...

Current ground penetrating radar based root analysis techniques have been mainly targeted for coarse root analysis. In order to extend the GPR technology to fine root analysis, it is necessary to design an unconventional GPR system that provides root information in the entire area under observation with greater accuracy and penetration depth. Specialized signal/image processing algorithms applicab ...

At present, CdZnTe is considered the material of choice for efficient, room temperature gamma-radiation detection systems used for the detection and identification of radionuclides. Despite the advances in CdZnTe materials technology during the last decade, the major impediments in the progress of - ray detection technology are the low yield of device quality materials and detectors, and the limit ...

DESCRIPTION (provided by applicant): The principle objective of this application is the development of safer and more effective combinatorial therapy for AD. ReXceptor, Inc. is developing new therapeutics for the treatment of AD based on stimulating the physiological clearance mechanisms of soluble forms of A from the brain. Bexarotene is an agonist of the ligand-activated transcription factor, r ...

Project Summary Human respiratory syncytial virus (RSV) is recognized as the single most important viral cause of acute respiratory disease in infants and young children worldwide. Elderly populations and immunocompromised individuals are also at significant risk for serious RSV disease. Despite this very substantial disease burden imposed by RSV worldwide, there are no vaccines available. Severa ...

DESCRIPTION (provided by applicant): While minimally invasive surgery has transformed the practice of surgery, access to implants for removal or alteration still requires surgery which generates risk and high cost. A next-generation approach is non-invasive, where implants are adjusted without an incision. There are clear applications in all fields of surgery, but particulary in orthopaedics wher ...

DESCRIPTION (provided by applicant): As cancer is one of the leading causes of death in the United States with some sub-types remaining essentially untreatable, expansion of available drug targets will provide significant new options for the development ofmore effective antineoplastic agents. The major goal of this project is to apply a unique drug discovery strategy to cancer drug development. Th ...

DESCRIPTION (provided by applicant): This project proposes to develop and evaluate a hand rehabilitation system for chronic hemiparetic stroke survivors that have lost their ability to full control their hand. Stroke is the leading cause of adult disability, and is the third leading cause of death in the United States. Stroke survivors often face a significant loss of functional motor control in ...

DESCRIPTION (provided by applicant): Scleroderma is a devastating autoimmune disease with a chronic course, involving the overproduction of collagen leading to fibrosis of the skin and connective tissues. The disease has a range of symptoms including pain,stiffness and swelling of the joints, shortness of breath and gastrointestinal complications. More than 50% of patients with the aggressive form ...