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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. A Chaperonin/Osmolyte Protein Folding Screen- STTR Phase I

    SBC: EDGE BIOSYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): One of the largest bottlenecks in high-throughput protein structure determination (structural genomics) and in subsequent drug targeting (pharmocogenomics) is the acquisition of soluble correctly folded functional protein products. Unfortunately, a large amount of the protein expression systems that are commonly used yield insoluble or soluble misfolded protein ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  2. A daily client check-in system for outpatient substance abuse treatment

    SBC: COG ANALYTICS, LLC            Topic: NIDA

    Abstract Alcohol and illicit drug use remain highly prevalent in the US, and epidemiological surveillance surveys estimate that over 20.6 million individuals (~ 8% of the US population) meet standard diagnostic thresholds for substance use disorders (SAMHSA, 2011). Outpatient substance abuse treatment is the predominate method of treatment in the US for SUDs, typically involving intermittent cont ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Algorithm Development for Reconfigurable Computing Architectures

    SBC: MNB TECHNOLOGIES, INC.            Topic: AF07T017

    High performance reconfigurable computing (HPRC) is an expanding technology offering workstations and small clusters performance levels previously reserved for large-scale systems populating the "Supercomputing 500" list. However, the lack of open-source libraries of generically applicable numeric methods (i.e. BLAS, LAPACK, Numeric Recipes, etc.) optimized for FPGA embodiment has hindered adopti ...

    STTR Phase I 2007 Department of DefenseAir Force
  4. Algorithm Development for Reconfigurable Computing Architectures

    SBC: Stone Ridge Technology, Inc.            Topic: AF07T017

    The demands of high performance engineering calculations have pushed modern computing architectures based on scalar multiprocessors to their very limits. Larger systems, unstructured grids, multi-scale and multi-phase requirements have all worked to dramatically increase problem complexity. This has created an urgent need for faster, more capable processing techniques. Implementing software algor ...

    STTR Phase I 2007 Department of DefenseAir Force
  5. A Millimeter-wave Tunable Cavity for Ultra-sensitive Solids and Liquids DNP-NMR at Low Budget

    SBC: DOTY SCIENTIFIC, INC.            Topic: NIA

    ? DESCRIPTION (provided by applicant): NMR is probably the most powerful and widely used analytical technique for structure determination and function elucidation of molecules of all types, but it suffers from low sensitivity, particularly for insoluble biological macromolecules. Dynamic Nuclear Polarization (DNP) with Magic Angle Spinning (MAS) has recently demonstrated S/N gains exceeding t ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. A Nanofluid with Superior Thermal Properties

    SBC: ATEC, Inc.            Topic: 11d

    Many industrial processes involve the transfer of heat from one medium to another. Thermal fluids and heat exchangers are often used as part of these processes. However, besides water or aqueous solutions, the other thermal fluids have thermal properties much lower than water, so larger heat exchangers or pumps are required. This project will develop a nanofluid with a nano-sized phase-change ...

    STTR Phase I 2007 Department of Energy
  7. A simple assay system for rapid detection of circulating tumor cells

    SBC: TELOVISION, LLC            Topic: NCI

    DESCRIPTION provided by applicant Metastasis or dissemination of primary tumor cells is the major cause of mortality in cancer patients Circulating tumor cells CTCs in the bloodstream are key players in the establishment of metastatic tumors Recent studies demonstrated that the number of CTCs present in patient blood directly correlate with cancer progression recurrence and survival rate ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Bio-Effects of Ultra-High MRI Gradient Slew Rates

    SBC: WEINBERG MEDICAL PHYSICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The spatial resolution and acquisition times for magnetic resonance imaging and spectroscopy could be improved through the application of more powerful and rapid magnetic gradients, thereby potentially leading to improv ed cardiac imaging and delineation and detection of cancers. Unfortunately, gradient field strength is limited by concerns about potential neur ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  9. Clinical Translation of Augmented Reality Visualization for Laparoscopic Surgery

    SBC: IGI TECHNOLOGIES, INC            Topic: NCI

    DESCRIPTION (provided by applicant): The overall objective of the proposed research is to fully develop and conduct clinical translation of a novel technology that provides minimally invasive surgeons an ability to visualize exposed organ surfaces as wellas structures hidden by them, together with a true appreciation of depth. A long-standing need in minimally invasive laparoscopic surgery has bee ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Cognitive Models for learning to control dynamic systems

    SBC: COMPUTELLIGENCE LLC            Topic: AF07T012

    The objective of this proposal is to demonstrate the feasibility of automated model development for dynamic system control based on action, event, and outcome sequences. The proposed approach focuses on the implementation of swarm intelligence algorithms that learn rapidly and adapt rapidly to non-stationary environments and scenarios with rapidly changing goals. The swarm intelligence-based mod ...

    STTR Phase I 2007 Department of DefenseAir Force
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