Award Data

DESCRIPTION provided by applicant One of the challenges of research in infectious diseases is to find ways to use the increasing knowledge of the mechanisms underlying disease transformation and progression to develop novel therapeutic strategies for diseases such as increasing menace of bacterial infections Targeting specific RNA such as rRNA which are involved in proliferation and survival ...

DESCRIPTION provided by applicant Duchenne Muscular Dystrophy DMD is a fatal muscle disease affecting in every male births DMD results from mutations in the gene encoding the dystrophin a kDa scaffolding protein responsible for providing a mechanical link between the muscle fiber actin cytoskeleton and a transmembrane protein complex called the dystrophin associated glycoprotein ...

DESCRIPTION provided by applicant Ovarian cancer is the fifth most leading cause of cancer related deaths in women in the US It has been observed that the cancer relapses within relatively short periods of time even after the surgery and chemotherapy Therefore immunotherapeutic strategies may serve as an alternative to control the recurrence or progression of ovarian cancer Oral vaccines ar ...

DESCRIPTION provided by applicant The number of Lyme disease cases in the US has been recently estimated by the CDC at cases year This is major public health concern Currently available diagnostics rely on detection of the antibody response serology to Borrelia burgdorferi the causative agent of Lyme disease However serological tests are not accurate during the early stages of Ly ...

DESCRIPTION provided by applicant Intracerebral hemorrhage ICH is a major public health problem with highest mortality rate of all stroke subtypes and long term disability Since there are no available FDA approved therapies for ICH it is of enormous importance to establish effective treatment for this medical condition Following ICH the deposited blood is damaging initially via compression ...

Millimeter and terahertz wave imaging can image objects behind or within other objects. However, current equipment that does this quickly is expensive, and affordable equipment is prohibitively slow. Researchers at Missouri S & T have successfully developed and demonstrated several innovative millimeter wave imaging systems capable of real-time, high-resolution imaging at frequencies up to 150 G ...

This STTR project seeks to overcome the performance limitations of experimental sulfur tolerant SOFC materials by combining two elements of efficient SOFC design: 1) micro-tubular arrays (OD

The objective of this proposal is to demonstrate the feasibility of producing large area, single crystal monolayer Molybdenum disulfide (MoS2) for high frequency applications. In order to be able to achieve this aim, it is necessary to work on three main components: (a) the channel material itself, (b) the gate dielectric and (c) the drain/ source contacts to the channel material. This work propo ...

The Department of Defense is concerned with circadian rhythm misalignments as they are known to affect judgment, psychomotor skills, and can lead to Post-Traumatic Stress Disorder (PTSD). At present, there is no comprehensive unobtrusive and easy-to-use solution that measures the circadian misalignment and automatically administers the appropriate therapy for realignment of circadian rhythm. Intel ...

In this STTR program, technology created at the University of California at Santa Barbara (UCSB) to fabricate silicon photonics based integrated laser devices, including wafer bonded gain elements, will be utilized to develop ultra-coherent integrated laser devices that are widely tunable. Novel laser designs developed by Morton Photonics, taking advantage of ultra-low loss microresonator based f ...