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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Synthesis of HRS-SSA linked data

    SBC: Aces Research LLC            Topic: N/A

    DESCRIPTION (provided by applicant): The Health and Retirement Study is one of the world's most important data resources for the study of aging. The basic longitudinal survey instrument has been supplemented with data from a variety of other sources including Social Security Administration records containing the detailed earnings history of the respondent. Under current HRS protocols, the use of t ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  2. A Chaperonin/Osmolyte Protein Folding Screen- STTR Phase I

    SBC: EDGE BIOSYSTEMS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): One of the largest bottlenecks in high-throughput protein structure determination (structural genomics) and in subsequent drug targeting (pharmocogenomics) is the acquisition of soluble correctly folded functional protein products. Unfortunately, a large amount of the protein expression systems that are commonly used yield insoluble or soluble misfolded protein ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  3. Long-term Ambulatory Gait Monitor for Parkinson's Disease

    SBC: IM SYSTEMS            Topic: N/A

    DESCRIPTION (provided by applicant): One of the primary and disabling clinical manifestations of Parkinson's disease (PD) is locomotor dysfunction, such as small, variable stride length and freezing of gait. Treatment of PD to a large extent focuses on replacing depleted dopamine at the striatum to maintain mobility for as long as possible. Clinical assessment relies on brief observation and frequ ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  4. Fieldtrip: Using Internet-Based Multi-Media to Engage Teens on Education Issues

    SBC: INFOCULTURE            Topic: N/A

    DESCRIPTION (provided by applicant): It is anticipated that only a third of today's high school students will go onto college despite consistent data that support the benefit of post-secondary education for individuals. Concurrently, daily Internet use among adolescents is nearing the fifty-percent mark, with broadband Internet steadily growing toward ubiquity. This project aims to leverage the ma ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  5. High Throughput web-base Image Analysis of Mouse Brain MR Imaging Studies

    SBC: KITWARE INC            Topic: N/A

    DESCRIPTION (provided by applicant): In the last decade, MRI studies of human brain morphometry have been used to investigate a multitude of pathologies and drug-related effects in psychiatric research. The morphometric measures that differentiate patient populations or track longitudinal changes are often subtle and require a large number of subjects or repeated studies to detect and statisticall ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  6. Computer Asistance for Targeting of Small Pulmonary Nodules in CT-Guided Biopsy

    SBC: KITWARE INC            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of this project is to develop a computer-aided system that can assist the radiologist in targeting small pulmonary nodules during CT-guided lung biopsy. The estimated 3D needle trajectory along with the range of potential needle trajectories given varying degrees of needle steering will be calculated and displayed to the radiologist. We believe ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  7. Lentiviral Redirected T Cells for B Cancer Immunotherapy

    SBC: LENTIGEN CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): Our long term goal is to develop cellular based immunotherapy for the treatment of malignancy. One approach to enhancing the effects of cellular immunotherapy is via gene therapy. We are currently focused on enhancing the antitumor effects of adoptive T cell therapy using lentiviral vector-mediated genetic modification of cells to express a universal T cell rec ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  8. Confocal Reflectance Microscope with Dual-Wedge Scanner

    SBC: LUCID, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of this project is to design, fabricate, and test a compact, low-cost, confocal reflectance microscope capable of producing images of skin with quality comparable to those of current commercial instruments. The new design uses a scanner concept in which the optical path is passed through two prisms, which are rotated about the beam axis, result ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  9. Fibronectin peptides for treatment of burns

    SBC: Neomatrix Therapeutics Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): There are more than 1 million burns each year in the US, resulting in 700,000 emergency department visits, 45,000 hospital admissions, and 4,500 deaths. Burns are dynamic injuries characterized by progressive extension of the injury over the first few days. Progression of partial thickness burns to full thickness injuries is associated with increases in mortali ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
  10. Functional Imaging of Freely Moving Animals

    SBC: Photon Migration Technologies Corp.            Topic: N/A

    DESCRIPTION (provided by applicant): We propose to develop a dual-mode, optical-EEG sensing system that provides for 4D functional imaging in freely moving animals. The proposed system employs a tethered arrangement that attaches to a two-stage detachable measuring head with one end surgically fixed to the head of a rat. This allows for concurrent collection of whole brain time-series DOT and mult ...

    STTR Phase I 2007 Department of Health and Human ServicesNational Institutes of Health
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