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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Novel fetal heart monitor technology
SBC: Bioconnexions, LLC Topic: N/ADESCRIPTION (provided by applicant): Significant progress has been made in the science of electrocardiography since 1938. Heart rate and biophysical profiles are routinely derived from multi-lead electrocardiograms (ECGs) in animals and humans after birth. In contrast, only limited heart monitoring technologies exist for the fetus. Moreover, available technology fails to satisfy many existing need ...
STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health -
ADULT HUMAN PROGENITOR CELLS FOR CARDIAC REGENERATION
SBC: KARDIA THERAPEUTICS, INC. Topic: N/ADESCRIPTION (provided by applicant): The ability to create new cardiac tissue using progenitor cells via engraftment would be a significant advance. However, the existing types of progenitor cells presently in Phase I clinical trials face significant limitations, including lack of evidence that the donor cells (1) produce new cardiac myocytes, versus creating benefits via neoangiogenesis or ventr ...
STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health -
Spinal Fusion Using Adipose Derived Adult Stem Cells
SBC: Cognate Therapeutics, Inc. Topic: N/ADESCRIPTION (provided by applicant): Back pain afflicts over 75% of Americans during their lifetime and 2% of the American work force suffers a back injury on the job each year. Spinal fusion is the orthopedic procedure routinely used to treat back pain in patients suffering from degenerative disc disease, spinal stenosis, scoliosis, and spinal fracture; however, procedure failure rates range betw ...
STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health -
Proactive Modulation of Strain for Ventricular Recovery
SBC: CORINNOVA, INC. Topic: N/ADESCRIPTION (provided by applicant): Congestive heart failure (CHF) is a debilitating condition that afflicts nearly 5 million Americans, and it has an increasing incidence. Despite improvements and enormous research efforts (both federally and commercially), pharmacological treatments are ineffective in many patients such that the demand for donor hearts is far greater than the supply. A primar ...
STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health -
Extended DNA amplification with thermostable chaperons
SBC: FIDELITY SYSTEMS, INC. Topic: N/ADESCRIPTION (provided by applicant): The goal of this project is to develop a general method of improving the stability and durability of enzymes used in DNA and RNA amplification, sequencing, restriction analysis and ligation. The enzymes to be improved include DNA polymerases, topoisomerases, reverse transcriptases and ligases. In the event this goal can be achieved, broad impacts may result in ...
STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health -
Restoration of vestibular hair cells induced by AdMath1
SBC: GENVEC, INC. Topic: N/ALoss of vestibular hair cells can occur due to a variety of disorders and results in dysfunction of the vestibulo-occular reflex and loss of balance. Bilateral vestibular hypofunction due to aminoglycoside ototoxicity and other means is a devastating and currently untreatable chronic disorder because loss of vestibular hair cells is permanent. To date there is no prosthetic device such as a hearin ...
STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health -
Submillimeter Technology for Molecular Biomarkers
SBC: LYNNTECH INC. Topic: N/ADESCRIPTION (provided by applicant): The ultimate objective of this research project will be the development and commercialization of a low cost, reliable and widely available point-of-care testing device for screening, diagnosis and management of disease in human patients. The proposed technique, submillimeter photoacoustic spectrometry of human breath, will initially be used to identify and q ...
STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health -
Feasibility study of a double fiber bundle dialyzer
SBC: MIRIMEDICAL, LLC. Topic: N/ADESCRIPTION (provided by applicant): Efficiency of hemodialysis is currently limited by dialyzer technology. Although new membranes with large surface areas have been developed, the increase in delivered treatment is only marginal. Double dialyzer therapies have been shown to be superior to standard high efficiency/ high flux dialysis treatments; however implementation of double dialyzer therapi ...
STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health -
Assessment of Altered Function in Diabetic Bladder
SBC: Neurotron, Inc. Topic: N/ADESCRIPTION (provided by applicant): Diabetic bladder dysfunction (DBD) or diabetic cystopathy is one of the most common and debilitating complications of diabetes mellitus (DM) affecting well over 50% of the patients with either type I or type II diabetes. DBD could affect both the filling and voiding function of the bladder leading to urinary incontinence, poor emptying, high post void residual ...
STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health -
Therapeutic Strategy for Recurrent Spontaneous Abortion
SBC: Nora, LLC Topic: N/ADESCRIPTION (provided by applicant): Recurrent spontaneous abortion (RSA) is a serious medical condition that affects approximately 1-3% of reproductive age women. At present, there is no FDA approved treatment for RSA. We hypothesize that failure to suppress Th1 cytokine production early in pregnancy is a major cause of RSA. We hypothesize that recombinant human granulocyte colony stimulating fa ...
STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health