Award Data

DESCRIPTION provided by applicant One of the challenges of research in infectious diseases is to find ways to use the increasing knowledge of the mechanisms underlying disease transformation and progression to develop novel therapeutic strategies for diseases such as increasing menace of bacterial infections Targeting specific RNA such as rRNA which are involved in proliferation and survival ...

DESCRIPTION provided by applicant Ovarian cancer is the fifth most leading cause of cancer related deaths in women in the US It has been observed that the cancer relapses within relatively short periods of time even after the surgery and chemotherapy Therefore immunotherapeutic strategies may serve as an alternative to control the recurrence or progression of ovarian cancer Oral vaccines ar ...

This effort proposes to design, develop and fabricate prototype SiGe MMICs that when combined with GaN MMICs forms the basis for additional simultaneous modes and more efficiency for the C-band Radar Automatic Collision Avoidance System (RACAS). The addition of these MMICs will enable digitally controlled pulse mode interleaving and switchable and simultaneous polarizations for enhanced Coherent A ...

The US Navy faces daunting energy challenges that will further increase in severity, given the ever-increasing global demand for energy, diminishing energy supplies and demand for enhanced environmental stewardship. Navys environment foot print consists of both emissions and noise generated every day around the world. Additionally, noise is an important issue for the Navy due to the adverse effect ...

DESCRIPTION provided by applicant Intracerebral hemorrhage ICH is a major public health problem with highest mortality rate of all stroke subtypes and long term disability Since there are no available FDA approved therapies for ICH it is of enormous importance to establish effective treatment for this medical condition Following ICH the deposited blood is damaging initially via compression ...

Pharad is teaming with the Applied Physics Laboratory of The Johns Hopkins University to propose and investigate the feasibility of wideband (VHF to SHF) RF-to-digital photonic link architectures with real-time digital signal processing (DSP) that can meet the stringent performance metrics of military systems. The key requirements for our wideband DSP linearized RF-to-digital photonic link include ...

Texas Research Institute Austin, Inc. (TRI/Austin) is developing a lithium-ion battery module that will manage individual cell thermal runaways in two ways. The active management path will be to monitor the internal temperature of the cell and remove the cell from the charging/discharging circuit if anode or cathode temperatures exceed specified temperatures. Removal from the charging/discharging ...

There is an ongoing effort to replace high activity radioactive sources that could pose a risk for use as terrorist weapons with non-radioisotope based technologies. Currently radioactive sources serve a number of critical needs including the treatment and diagnosis of disease, inspection and certification of critical mechanical structures, the sterilization of food and medical products, ...

At present, CdZnTe is considered the material of choice for efficient, room temperature gamma-radiation detection systems used for the detection and identification of radionuclides. Despite the advances in CdZnTe materials technology during the last decade, the major impediments in the progress of - ray detection technology are the low yield of device quality materials and detectors, and the limit ...

This Phase I SBIR/STTR will establish the feasibility of developing a precision balanced optical cross-correlator using engineered nonlinear optical waveguides. The proposed device will be important for future advances at large scale accelerator facilities by providing a means to achieve long-term sub- femtosecond timing and synchronization of all of a facilitys optical and RF sub-systems over fib ...