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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Development of Peptide Antibiotic Nucleic Acids

    SBC: NUBAD, LLC            Topic: NIAID

    DESCRIPTION provided by applicant One of the challenges of research in infectious diseases is to find ways to use the increasing knowledge of the mechanisms underlying disease transformation and progression to develop novel therapeutic strategies for diseases such as increasing menace of bacterial infections Targeting specific RNA such as rRNA which are involved in proliferation and survival ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Ovarian cancer using novel nanoparticle formulations

    SBC: Kiromic BioPharma, Inc.            Topic: 102

    DESCRIPTION provided by applicant Ovarian cancer is the fifth most leading cause of cancer related deaths in women in the US It has been observed that the cancer relapses within relatively short periods of time even after the surgery and chemotherapy Therefore immunotherapeutic strategies may serve as an alternative to control the recurrence or progression of ovarian cancer Oral vaccines ar ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Optimized lactoferrin for treatment of intracerebral hemorrhage

    SBC: Pharmareview Corporation            Topic: NINDS

    DESCRIPTION provided by applicant Intracerebral hemorrhage ICH is a major public health problem with highest mortality rate of all stroke subtypes and long term disability Since there are no available FDA approved therapies for ICH it is of enormous importance to establish effective treatment for this medical condition Following ICH the deposited blood is damaging initially via compression ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Mitigation of sand mold related metal casting defects through virtual manufacturing

    SBC: Mold Dynamics            Topic: 02a

    Metal casting is an important manufacturing process and most castings are made by small to mid-sized foundries. Sand molded castings account for 85% of all iron and steel castings produced and approximately 5 out of 30 major casting defects including gas blows and sand burn-on are related to poor sand mold atmosphere control. Mold atmosphere control should become more crucial in the coming years a ...

    STTR Phase I 2014 Department of Energy
  5. Uniform, High Intensity X-ray Source for Blood Irradiation

    SBC: National Nanomaterials, Inc            Topic: 22a

    There is an ongoing effort to replace high activity radioactive sources that could pose a risk for use as terrorist weapons with non-radioisotope based technologies. Currently radioactive sources serve a number of critical needs including the treatment and diagnosis of disease, inspection and certification of critical mechanical structures, the sterilization of food and medical products, ...

    STTR Phase I 2014 Department of Energy
  6. Next Generation Semiconductor-Based Radiation Detectors Using Cadmium Magnesium Telluride

    SBC: BRIMROSE TECHNOLOGY CORPORATION            Topic: 23c

    At present, CdZnTe is considered the material of choice for efficient, room temperature gamma-radiation detection systems used for the detection and identification of radionuclides. Despite the advances in CdZnTe materials technology during the last decade, the major impediments in the progress of - ray detection technology are the low yield of device quality materials and detectors, and the limit ...

    STTR Phase I 2014 Department of Energy
  7. Standoff Detection of Radiological Materials using Light Filaments

    SBC: Southwest Sciences, Inc.            Topic: 27a

    The ability to detect radiological materials at standoff distances of a kilometer or more would be invaluable to national security and nonproliferation efforts. In particular, it is important to be able to distinguish isotopes of uranium and other elements associated with nuclear weapons development and use. Current methods for identifying radiological isotopes require direct sampling. Laser ba ...

    STTR Phase I 2014 Department of Energy
  8. Diamond sensor for the neutron electric dipole moment experiment

    SBC: Southwest Sciences, Inc.            Topic: 39g

    As part of its mission to understand the fundamental forces and particles of nature as manifested in nuclear matter, DOE is funding an experiment to measure the electric dipole moment of neutron. This sophisticated experiment tests the standard model by monitoring the response of neutrons in crossed electric and magnetic fields. This Phase I project will investigate a method for measuring the str ...

    STTR Phase I 2014 Department of Energy
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