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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Development of Peptide Antibiotic Nucleic Acids

    SBC: NUBAD, LLC            Topic: NIAID

    DESCRIPTION provided by applicant One of the challenges of research in infectious diseases is to find ways to use the increasing knowledge of the mechanisms underlying disease transformation and progression to develop novel therapeutic strategies for diseases such as increasing menace of bacterial infections Targeting specific RNA such as rRNA which are involved in proliferation and survival ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Ovarian cancer using novel nanoparticle formulations

    SBC: Kiromic BioPharma, Inc.            Topic: 102

    DESCRIPTION provided by applicant Ovarian cancer is the fifth most leading cause of cancer related deaths in women in the US It has been observed that the cancer relapses within relatively short periods of time even after the surgery and chemotherapy Therefore immunotherapeutic strategies may serve as an alternative to control the recurrence or progression of ovarian cancer Oral vaccines ar ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Optimized lactoferrin for treatment of intracerebral hemorrhage

    SBC: Pharmareview Corporation            Topic: NINDS

    DESCRIPTION provided by applicant Intracerebral hemorrhage ICH is a major public health problem with highest mortality rate of all stroke subtypes and long term disability Since there are no available FDA approved therapies for ICH it is of enormous importance to establish effective treatment for this medical condition Following ICH the deposited blood is damaging initially via compression ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Uniform, High Intensity X-ray Source for Blood Irradiation

    SBC: National Nanomaterials, Inc            Topic: 22a

    There is an ongoing effort to replace high activity radioactive sources that could pose a risk for use as terrorist weapons with non-radioisotope based technologies. Currently radioactive sources serve a number of critical needs including the treatment and diagnosis of disease, inspection and certification of critical mechanical structures, the sterilization of food and medical products, ...

    STTR Phase I 2014 Department of Energy
  5. Next Generation Semiconductor-Based Radiation Detectors Using Cadmium Magnesium Telluride

    SBC: BRIMROSE TECHNOLOGY CORPORATION            Topic: 23c

    At present, CdZnTe is considered the material of choice for efficient, room temperature gamma-radiation detection systems used for the detection and identification of radionuclides. Despite the advances in CdZnTe materials technology during the last decade, the major impediments in the progress of - ray detection technology are the low yield of device quality materials and detectors, and the limit ...

    STTR Phase I 2014 Department of Energy
  6. Automated Cache Performance Analysis and Optimization in Open|SpeedShop

    SBC: ARGO NAVIS TECHNOLOGIES, LLC            Topic: 02b

    While there is no lack of performance counter tools for coarse-grained measurement of cache activity, there is a critical lack of tools for relating data layout to cache behavior to application performance. Generally, any nontrivial optimizations are either not done at all, or are done by hand requiring significant time and expertise. To the best of our knowledge no tool available to users measure ...

    STTR Phase I 2013 Department of Energy
  7. Laser Cladding Applied to the Construction of PFCs with Integral Tritium Diffusion Barriers

    SBC: NANOHMICS INC            Topic: 27b

    Selection of the Plasma-Facing Component (PFC) material composition is a primary consideration in future fusion reactor design. The PFC materials must not only withstand the harsh operating conditions of the reactor, but the amount of tritium uptake experienced by the PFC during operation is a significant factor. Proper operation, safety and environmental impact mandate that t ...

    STTR Phase I 2013 Department of Energy
  8. Rotating Liner Engine: Improving Efficiency of Heavy Duty Diesels by Significant Friction Reduction, and Extending The Life of Heavy Duty Engines.

    SBC: Rotating Sleeve Engine Technologies Inc.            Topic: 06h

    The ultimate goal of the project is to demonstrate that the rotating liner engine (RLE) can increase fuel efficiency in heavy duty vehicles by about 3.5-4% at full load, about 25% at idle, and about 10% for an average duty cycle, can reduce CO2, NOx and PM and reduce engine wear. Design already completed. The face seal is the only technical challenge of the concept, and the main design features pe ...

    STTR Phase I 2013 Department of Energy
  9. Carbon Nanotube-based Solar Water Heater

    SBC: SOLARNO, INC            Topic: 03e

    Solar water heaters are a well-established renewable energy technology that has been widely adopted outside of the United States. Here we propose to significantly improve the evacuated solar tube collectors (ETC) by utilizing the dry-drawable carbon nanotube (CNT) sheets for solar energy absorption and CNT multifunctional nanocomposites with functional layers of heat accumulators and heat transpo ...

    STTR Phase I 2013 Department of Energy
  10. High Efficiency Thin Film Thermoelectric Generators (HiE TFTEGs) for Vehicles

    SBC: Sheetak Inc.            Topic: 06f

    A significant portion of the waste heat from engine exhaust can be recovered using thermoelectric generators to achieve up to 10% gain in automotive mileage. There have been several efforts underway on this front but most have focused on demonstrating thermoelectric generators using bulk materials that consume significant amount of raw materials and are prone to failures due to thermal expansion, ...

    STTR Phase I 2013 Department of Energy
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