Award Data

DESCRIPTION provided by applicant Seasonal influenza flu virus an NIAID category C priority pathogen causes widespread infection resulting in at least million cases of severe illness and deaths worldwide Young children and elderly or immunocompromised individuals are typically at greater risk of severe illness or death from influenza Newly emerging strains can result ...

DESCRIPTION provided by applicant One of the challenges of research in infectious diseases is to find ways to use the increasing knowledge of the mechanisms underlying disease transformation and progression to develop novel therapeutic strategies for diseases such as increasing menace of bacterial infections Targeting specific RNA such as rRNA which are involved in proliferation and survival ...

DESCRIPTION provided by applicant Ovarian cancer is the fifth most leading cause of cancer related deaths in women in the US It has been observed that the cancer relapses within relatively short periods of time even after the surgery and chemotherapy Therefore immunotherapeutic strategies may serve as an alternative to control the recurrence or progression of ovarian cancer Oral vaccines ar ...

DESCRIPTION provided by applicant Intracerebral hemorrhage ICH is a major public health problem with highest mortality rate of all stroke subtypes and long term disability Since there are no available FDA approved therapies for ICH it is of enormous importance to establish effective treatment for this medical condition Following ICH the deposited blood is damaging initially via compression ...

This Small Business Technology Transfer Phase I project focuses on designing an eco-friendly, inexpensive cement hydrate with superior mechanical properties and applicable to several structural components. Cement is the key strengthening ingredient in concrete, the production of which accounts for ~2-3% of global energy use, and 5-10% of worldwide CO2 emissions. There is currently no other materia ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is found in the proposed technology development that facilitates direct, ubiquitous acquisition of key biomedical data, with little or no human intervention or introduction of errors, has the potential to reduce the costs of healthcare and to revolutionize healthcare delivery throughout our so ...

The broader impact/commercial potential of this project is determined by new consumer products and new industries which would flourish on portable and reliable atomic clocks, gyroscopes, and magnetometers when they become available. Proposed compact thermal and magnetic enclosure reduces the most bulky part of such devices and provides an avenue for further miniaturization. A chip-scale atomic clo ...

The broader impact/commercial impact of this Small Business Technology Transfer (STTR) Phase I project is development of a pulmonary function testing device for detection and diagnosis of pulmonary conditions. Today more than 650 million globally, nearly 10% of the world?s population, suffers from lung conditions like Asthma and Chronic Obstructive Pulmonary Disease (COPD). Currently, the most wel ...

Millimeter and terahertz wave imaging can image objects behind or within other objects. However, current equipment that does this quickly is expensive, and affordable equipment is prohibitively slow. Researchers at Missouri S & T have successfully developed and demonstrated several innovative millimeter wave imaging systems capable of real-time, high-resolution imaging at frequencies up to 150 G ...

This STTR project seeks to overcome the performance limitations of experimental sulfur tolerant SOFC materials by combining two elements of efficient SOFC design: 1) micro-tubular arrays (OD