Award Data

DESCRIPTION provided by applicant Seasonal influenza flu virus an NIAID category C priority pathogen causes widespread infection resulting in at least million cases of severe illness and deaths worldwide Young children and elderly or immunocompromised individuals are typically at greater risk of severe illness or death from influenza Newly emerging strains can result ...

DESCRIPTION provided by applicant One of the challenges of research in infectious diseases is to find ways to use the increasing knowledge of the mechanisms underlying disease transformation and progression to develop novel therapeutic strategies for diseases such as increasing menace of bacterial infections Targeting specific RNA such as rRNA which are involved in proliferation and survival ...

This Small Business Innovation Research (SBIR) Phase I project is designed to address the emerging need for evaluation of mHealth applications (apps). The goal of our project is to ?break down the ivory tower wall of academic medical research? and design a Platform as a Service (PaaS) to allow app developers to conduct rigorous evaluation. Through market-driven design and application of fundamenta ...

This STTR Phase I project proposes to develop and validate a student centered adaptive learning engine that is focused on improving learning outcomes using data collected from new and existing educational technology projects combined with advanced technology to automatically generate adaptive capabilities, thus creating ready-to-go intelligent tutoring systems. Providing adaptive instruction to st ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is found in the proposed technology development that facilitates direct, ubiquitous acquisition of key biomedical data, with little or no human intervention or introduction of errors, has the potential to reduce the costs of healthcare and to revolutionize healthcare delivery throughout our so ...

The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project, in which a new device and approach to weaning patients from mechanical ventilation is proposed, is a reduction in public health care expenditure and a reduction in morbidity for the half a million patients who have difficulty weaning from mechanical ventilation each year in the US. This proje ...

The broader impact/commercial potential of this project is determined by new consumer products and new industries which would flourish on portable and reliable atomic clocks, gyroscopes, and magnetometers when they become available. Proposed compact thermal and magnetic enclosure reduces the most bulky part of such devices and provides an avenue for further miniaturization. A chip-scale atomic clo ...

This Small Business Technology Transfer (STTR) Phase I project aims to apply knowledge developed from a laboratory astrophysics experiment to the challenge of purification of aluminum. Aluminum more readily oxidizes than any metallic impurities such as iron, which makes purifying aluminum cost prohibitive. This project began as an investigation in liquid metal of angular momentum transport mechani ...

This Small Business Technology Transfer Research (STTR) Phase I project is seeking to develop a novel cost-effective strategy to modify dental implants with biomimetic nanofibers for controlled regeneration of gingival tissue. In order to seal the dental implants from bacteria and consequently protect the crestal bone from infection-induced deterioration, there is an unmet need to promote a prompt ...

This SBIR Phase I project proposes to demonstrate the feasibility of delivering a radically game-changing Big Data - based Supply Chain Analytics Platform. A complex supply chain, in consumer goods manufacturing and distribution, for example, involves data analysis and decision support in many areas. Today's tools and techniques used in supply chain analytics are too restrictive as they rely ...