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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Aminoglycosides with reduced ototoxicity

    SBC: NUBAD, LLC            Topic: NIAID

    PROJECT SUMMARY Aminoglycosides are one of the cheapest and well known antibiotics in clinical use for over years but one of the major limitations in their use is their ototoxicity We are developing fast and low cost methods to develop aminoglycosides with anti ribosomal activities and reduced toxicity In this project we will identify novel aminoglycoside antibacterials that show reduced ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Screening the Ribosome for New Target Sites

    SBC: NUBAD, LLC            Topic: NIAID

    DESCRIPTION provided by applicant Nucleic acids are avenues for drug design both as therapeutics and as targets Here we propose to establish new methods for identifying antibiotic ribosome targets and lead compounds Targeting specific RNA such as rRNA which are involved in proliferation and survival of bacteria is a promising approach We are developing fast and low cost methods to screen s ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. Treating collagen induced arthritis CIA with immunoregulatory nanoparticles

    SBC: LeukoSight Inc            Topic: NIAMS

    DESCRIPTION provided by applicant The title of this project is andquot Treating Collagen induced Arthritis with Fc Receptor Activating Nanoparticlesandquot We and others have identified and characterized a population of macrophages with potent immunorergulatory activity The goal of the present proposal is to induce the production of regulatory macrophages R M in mice and determine wheth ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Development of a novel highly effective influenza vaccine

    SBC: Flugen, Inc.            Topic: NIAID

    DESCRIPTION provided by applicant Seasonal influenza flu virus an NIAID category C priority pathogen causes widespread infection resulting in at least million cases of severe illness and deaths worldwide Young children and elderly or immunocompromised individuals are typically at greater risk of severe illness or death from influenza Newly emerging strains can result ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Development of Peptide Antibiotic Nucleic Acids

    SBC: NUBAD, LLC            Topic: NIAID

    DESCRIPTION provided by applicant One of the challenges of research in infectious diseases is to find ways to use the increasing knowledge of the mechanisms underlying disease transformation and progression to develop novel therapeutic strategies for diseases such as increasing menace of bacterial infections Targeting specific RNA such as rRNA which are involved in proliferation and survival ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. STTR Phase I: Ultra-large and low-cost electrodynamic modeling in commercial clouds

    SBC: FLEXCOMPUTE INC            Topic: PH

    The broader impact/commercial potential of this Small Business Innovation Research Phase I project is to enable anyone with internet to access extremely powerful computing facilities to perform scientific computing. High performance computing is essential for computational prototyping in many areas of modern engineering, such as solar cells, automobiles, aerospace, and communication devices. Howev ...

    STTR Phase I 2016 National Science Foundation
  7. STTR Phase I: SunDIAL: Slot DIscovery And Linking

    SBC: RedShred, LLC            Topic: IT

    The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project results from it improving the accessibility of documents and providing a powerful tool for consumers and businesses to enable routing, categorizing, and understanding of documents. By producing summaries of opportunity documents for business developers, SunDIAL will accelerate pipeline and bus ...

    STTR Phase I 2016 National Science Foundation
  8. STTR Phase I: Lightweight Self-Lubricating Cylinder Liners for IC Engines to Conserve Energy and Reduce Emissions

    SBC: Intelligent Composites LLC            Topic: MI

    This Small Business Technology Transfer Phase I project will investigate a hybrid, lightweight aluminum self-lubricating composite system which has promise to reduce friction and improve performance of cylinder liners in internal combustion engines. Friction between moving parts in an internal combustion engine, especially between the piston rings and cylinder liner, accounts for a large percentag ...

    STTR Phase I 2016 National Science Foundation
  9. STTR Phase I: 24x7 mobile wireless monitoring of patient's vitals to proactively manage disease recovery

    SBC: Argosy Omnimedia, Inc.            Topic: SH

    The broader impact/commercial potential of this Small Business Technology Transfer (STTR) Phase I project is found in the proposed technology development that facilitates direct, ubiquitous acquisition of key biomedical data, with little or no human intervention or introduction of errors, has the potential to reduce the costs of healthcare and to revolutionize healthcare delivery throughout our so ...

    STTR Phase I 2014 National Science Foundation
  10. STTR Phase I: Ferrofluidic enclosures for enhanced control of thermal and magnetic fields in spin-stabilized atomic micro-devices

    SBC: COMMET LLC            Topic: EW

    The broader impact/commercial potential of this project is determined by new consumer products and new industries which would flourish on portable and reliable atomic clocks, gyroscopes, and magnetometers when they become available. Proposed compact thermal and magnetic enclosure reduces the most bulky part of such devices and provides an avenue for further miniaturization. A chip-scale atomic clo ...

    STTR Phase I 2014 National Science Foundation
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