Award Data

DESCRIPTION provided by applicant In this project we will develop a commercial resource for the automated analysis of brain anatomy based on MRI This product is based on the whole brain parcellation algorithm with the following unique features First it is based on a cutting edge multi atlas approach in which we will incorporate rich atlas resources from Dr Moriandapos s lab at the Johns ...

DESCRIPTION provided by applicant Improvements in pre hospital trauma life support in the past years have led to impressive enhancement in patient survival These achievements have come as the result of improved equipment transport logistics assessment treatment protocols and training of personnel in all levels of the care chain from the point of injury to th hospital One of the areas th ...

DESCRIPTION provided by applicant In an effort to reduce the use of animals for toxicity testing companies have developed in vitro skin models or equivalents to replace the Draize skin irritation test This development has been further pushed by the European Union regulation that has prohibited the use of animals for collecting toxicological data on cosmetic ingredients that began Supply ...

DESCRIPTION provided by applicant Alcohol misuse continues to pose a major burden for public health Screening and brief intervention for alcohol misuse in primary care settings has been recommended for decades and the evidence base supporting it in primary care is robust However many primary care providers do not intervene in alcohol misuse and those that do often fail to do so systematica ...

DESCRIPTION provided by applicant Monoclonal antibodies mAbs have become the leading drug class for cancer treatment and over anti neoplastic mAbs are in the biopharmaceutical pipeline Most mAb therapies must be administered in doses of mg kg resulting in per patient costs of up to $ per year The high price of mAb therapy causes a significant financial burden for patients ...

DESCRIPTION provided by applicant Both primary and metastatic liver cancer is common in the US and worldwide The standard treatment for liver cancer is liver resection where part of the liver containing the tumor is surgically removed This operation is associated with considerable blood loss typically between L Blood loss is adversely associated with patient morbidity and survival ...

DESCRIPTION provided by applicant The goal of this Phase I Phase II Fast Track application is to develop and evaluate a simulation based product for training student affairs staff e g resident assistants RAs Greek life staff campus and housing security student conduct staff and academic advisors to assess and provide appropriate intervention to students who engage in risky drinking be ...

DESCRIPTION provided by applicant Diffusion Weighted Imaging DWI has the potential for being a safe cost effective alternative to ultrasound as a supplemental procedure to mammography for screening the of women with dense breasts to identify women who have suspicious breasts lesions The investigators have developed two patent pending methods for improving sensitivity in detection o ...

DESCRIPTION provided by applicant Cardiomyopathy has various forms including hypertrophic cardiomyopathy HCM in prevalence could cause sudden cardiac death in athletes Dilated Cardiomyopathy DCM in prevalence results in an enlarge left ventricle Arrhythmogenic Right Ventricular Dysplasia Cardiomyopathy ARVD C in prevalence causes cardiac fibrosis Yearly over $ ...

DESCRIPTION provided by applicant Therapeutic monoclonal antibodies bind to specific regions of proteins called epitopes which elicits cellular responses Traditional antibody discovery processes require laborious and expensive screening experiments so computational approaches that predict epitopes and accelerate antibody discovery are in high demand Structure based antibody design is also i ...