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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Development of Software for Automated Quantification of Brain MR Images

    SBC: ANATOMYWORKS, LLC            Topic: 108

    DESCRIPTION provided by applicant In this project we will develop a commercial resource for the automated analysis of brain anatomy based on MRI This product is based on the whole brain parcellation algorithm with the following unique features First it is based on a cutting edge multi atlas approach in which we will incorporate rich atlas resources from Dr Moriandapos s lab at the Johns ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Augmented Reality System to Teach Hemostatic Agent Use in Hemorrhage Control

    SBC: SIMQUEST INTERNATIONAL, LLC            Topic: 300

    DESCRIPTION provided by applicant Improvements in pre hospital trauma life support in the past years have led to impressive enhancement in patient survival These achievements have come as the result of improved equipment transport logistics assessment treatment protocols and training of personnel in all levels of the care chain from the point of injury to th hospital One of the areas th ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Cryopreservation of Engineered Tissue Equivalents

    SBC: TISSUE TESTING TECHNOLOGIES LLC            Topic: 300

    DESCRIPTION provided by applicant In an effort to reduce the use of animals for toxicity testing companies have developed in vitro skin models or equivalents to replace the Draize skin irritation test This development has been further pushed by the European Union regulation that has prohibited the use of animals for collecting toxicological data on cosmetic ingredients that began Supply ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Micro-targeted Computerized Alcohol Misuse Intervention System for Health Care

    SBC: RESEARCH CIRCLE ASSOCIATES            Topic: NIAAA

    DESCRIPTION provided by applicant Alcohol misuse continues to pose a major burden for public health Screening and brief intervention for alcohol misuse in primary care settings has been recommended for decades and the evidence base supporting it in primary care is robust However many primary care providers do not intervene in alcohol misuse and those that do often fail to do so systematica ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Continuous Chromatography Device to Economically Purify Clinical-grade Antibodies

    SBC: Semba Biosciences Inc            Topic: 102

    DESCRIPTION provided by applicant Monoclonal antibodies mAbs have become the leading drug class for cancer treatment and over anti neoplastic mAbs are in the biopharmaceutical pipeline Most mAb therapies must be administered in doses of mg kg resulting in per patient costs of up to $ per year The high price of mAb therapy causes a significant financial burden for patients ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Electrode Arrays for Bloodless Liver Resection and Tumor Ablation

    SBC: MEDICAL ENGINEERING INNOVATIONS, LLC            Topic: 102

    DESCRIPTION provided by applicant Both primary and metastatic liver cancer is common in the US and worldwide The standard treatment for liver cancer is liver resection where part of the liver containing the tumor is surgically removed This operation is associated with considerable blood loss typically between L Blood loss is adversely associated with patient morbidity and survival ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  7. College Alcohol Assessment and Intervention Training Simulation

    SBC: SIMmersion L.L.C.            Topic: 400

    DESCRIPTION provided by applicant The goal of this Phase I Phase II Fast Track application is to develop and evaluate a simulation based product for training student affairs staff e g resident assistants RAs Greek life staff campus and housing security student conduct staff and academic advisors to assess and provide appropriate intervention to students who engage in risky drinking be ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Diffusion Weighted Breast MR Imaging for Screening Women with Dense Breasts

    SBC: Alan Penn & Associates Inc            Topic: 102

    DESCRIPTION provided by applicant Diffusion Weighted Imaging DWI has the potential for being a safe cost effective alternative to ultrasound as a supplemental procedure to mammography for screening the of women with dense breasts to identify women who have suspicious breasts lesions The investigators have developed two patent pending methods for improving sensitivity in detection o ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  9. MASS PRODUCTION OF PERSONALIZED HUMAN ENGINEERED HEART TISSUES

    SBC: Invivosciences, Inc.            Topic: 200

    DESCRIPTION provided by applicant Cardiomyopathy has various forms including hypertrophic cardiomyopathy HCM in prevalence could cause sudden cardiac death in athletes Dilated Cardiomyopathy DCM in prevalence results in an enlarge left ventricle Arrhythmogenic Right Ventricular Dysplasia Cardiomyopathy ARVD C in prevalence causes cardiac fibrosis Yearly over $ ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Structural bioinformatics software for epitope selection and antibody engineering

    SBC: DNASTAR, INC.            Topic: 100

    DESCRIPTION provided by applicant Therapeutic monoclonal antibodies bind to specific regions of proteins called epitopes which elicits cellular responses Traditional antibody discovery processes require laborious and expensive screening experiments so computational approaches that predict epitopes and accelerate antibody discovery are in high demand Structure based antibody design is also i ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
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