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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. ARCHER- An Extremely Fast Medical Radiation Dose Computing Software

    SBC: VIRTUAL PHANTOMS INC            Topic: NIBIB

    DESCRIPTION provided by applicant The goal of this project is to develop a commercial software package for rapid Monte Carlo based dose computation in imaging and radiation therapy The product takes advantage of a desktop parallel computer equipped with emerging hardware originally developed gaming and high performance computing The project is motivated by the fact that the market is ripe for ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Multi-Modality Image Data Fusion and Machine Learning Approaches for Personalized Diagnostics and Prognostics of MCI due to AD

    SBC: MS Technologies Corporation            Topic: NIA

    Alzheimer s Disease AD is the most common form of dementia and the sixth leading cause of death in the US More than million people in the US currently have AD and the direct health care cost is over $ billion per year Detection of early phase of AD namely Mild Cognitive Impairment MCI can delay prevent and treat this serious disease The project will develop a clinically feasible sy ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  3. A NEW HOLOGRAPHIC 3D CAMERA FOR FUNDUS IMAGING

    SBC: CELLOPTIC            Topic: N

    A NEW HOLOGRAPHIC D CAMERA FOR FUNDUS IMAGING Abstract In the United States retinal disease is the most common cause of visual impairment with age related macular degeneration AMD and diabetic retinopathy DR being the most common retinal diseases For each of the above conditions high resolution and three dimensional D imaging of the retina retinal vasculature choroid and or retinal ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Proteasome inhibitor re-sensitizing molecules for treatment of refractory multiple myeloma

    SBC: Leukogene Therapeutics Inc.            Topic: 102

    Project Summary Abstract Multiple Myeloma MM is the second most common form of blood cancer and remains an incurable and deadly disease Proteasome inhibitor PI therapy is a cornerstone in the treatment of MM but resistance to this class of agent is an emerging challenge in the clinic New therapeutic approaches that specifically target resistance are needed to maximize responses and ultimate ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  5. Treating collagen induced arthritis CIA with immunoregulatory nanoparticles

    SBC: LeukoSight Inc            Topic: NIAMS

    DESCRIPTION provided by applicant The title of this project is andquot Treating Collagen induced Arthritis with Fc Receptor Activating Nanoparticlesandquot We and others have identified and characterized a population of macrophages with potent immunorergulatory activity The goal of the present proposal is to induce the production of regulatory macrophages R M in mice and determine wheth ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  6. Novel noninvasive diagnostic technology for dynamic imaging of mitochondrial bioenergetics in breast cancer patients

    SBC: Robin Medical, Inc.            Topic: 102

    Summary Breast cancer is the second most common and the major cause of cancer related death of women in the USA The last decade has witnessed major advancement of therapeutic drugs and tools while noninvasive diagnostic imaging tools to measure interventions received much less attention Currently the mainstay of noninvasive imaging in breast cancer relies primarily on anatomic imaging Metabol ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  7. Memory Lane: A neuro-exergame to mitigate cognitive decline in later life

    SBC: 1ST PLAYABLE PRODUCTIONS LLC            Topic: NIA

    DESCRIPTION provided by applicant st Playable Productions and Union College propose to develop a commercializable product combining physical exercise and cognitive activities through interactive gaming on a stationary bicycle to help prevent cognitive decline and dementia in older adults The Interactive Physical and Cognitive Exercise System iPACES developed by Union Collegeandapos s Health ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  8. A Novel Biologic for the Treatment of Hypogonadism

    SBC: JangoBio, LLC            Topic: N

    DESCRIPTION provided by applicant Male hypogonadism results from failure of the testes to produce sufficient sex hormones Aging is the greatest cause of primary hypogonadism otherwise known as testosterone deficiency syndrome TDS and in the United States affects million men while undiagnosed cases of TDS are upwards of million men TDS adversely affects male health and has been lin ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  9. Streamlining HTS Assay Development through Direct Selection of Structure-Switching Aptamers

    SBC: Bellbrook Labs, LLC            Topic: 300

    Project Summary Abstract High throughput screening HTS is a powerful method for the discovery of new drug leads for target enzymes In HTS assays the activity of the target enzyme is often evaluated by quantifying a small molecule or cofactor that is produced or consumed by the enzyme While antibodies are a mainstay of small molecule detection as says they do have severe limitations which a ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  10. Automated Point-of-Care Identification of Innocent Still's Murmur in Children

    SBC: AUSCULTECH DX LLC            Topic: NHLBI

    PROJECT SUMMARY The overall goal of the proposed research and technology transfer effort is to develop a low cost point of care mobile device based technology for automated identification of Stillandapos s murmur the most common innocent benign and harmless heart murmur of childhood This novel technology could reduce the current rate of over a million children unnecessarily referred to pedia ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
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