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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Development of a novel highly effective influenza vaccine
SBC: FLUGEN INC Topic: NIAIDDESCRIPTION provided by applicant Seasonal influenza flu virus an NIAID category C priority pathogen causes widespread infection resulting in at least million cases of severe illness and deaths worldwide Young children and elderly or immunocompromised individuals are typically at greater risk of severe illness or death from influenza Newly emerging strains can result ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Development of Peptide Antibiotic Nucleic Acids
SBC: NUBAD LLC Topic: NIAIDDESCRIPTION provided by applicant One of the challenges of research in infectious diseases is to find ways to use the increasing knowledge of the mechanisms underlying disease transformation and progression to develop novel therapeutic strategies for diseases such as increasing menace of bacterial infections Targeting specific RNA such as rRNA which are involved in proliferation and survival ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Rabbit InMAD Discovery of Novel Biomarkers for POC Tuberculosis Diagnostic Assay
SBC: Immuno-mycologics, Inc. Topic: NIAIDDESCRIPTION provided by applicant Tuberculosis TB is a chronic infectious disease that infects approximately one third of the worldandapos s population Eighty five percent of the estimated million new cases of TB in occurred in resource limited countries located in Asia and Africa In there were million deaths from TB among HIV negative patients and additional TB d ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
NON-NATURAL AMINO ACIDS IN PEPTIDE DRUG DEVELOPMENT
SBC: ARGOLYN BIOSCIENCE, INC. Topic: N/AArgolyn Bioscience Inc. is an early stage biotechnology company that creates novel peptide drugs and diagnostics with greatly improved intrinsic pharmaceutical properties through substitution of non-natural amino acid analogues for arginine (Arg) or lysine (Lys). In proof-of concept studies thus far, application of the Argolyn technology to peptides of therapeutic interest has resulted in dramatic ...
STTR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health -
NOVEL NEUROTENSIN ANALOGS AS ANTISCHIZOPRENICS
SBC: ARGOLYN BIOSCIENCE, INC. Topic: N/ADESCRIPTION (provided by applicant): The brain peptide neurotensin (NT) and its active derivative NT [8-13] function as endogenous neuroleptics. Stable NT derivatives that cross the blood brain barrier therefore have significant potential for development as a new class of non-dopamineric antipsychotics expected not to display the adverse side effects associated with the dopaminergics. The best lit ...
STTR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health -
FINE NEEDLE ASPIRATION BIOPSY(FNAB) NEEDLE DEVICE
SBC: BIOINNOVATION, LLC Topic: N/AFine Needle Aspiration Biopsies (FNAB) are widely performed due to their minimally invasive nature, low cost, and rapid turn around time for the diagnosis of various mass lesions such as cancer and infection. With increasingly, their use is expected to increase further mainly due to the escalating incidence of cancer. In the future, with the prevalence of in s- situ molecular techniques., FNAB wil ...
STTR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health -
DETECTION OF PRION PROTEIN IN BLOOD
SBC: SERACARE LIFE SCIENCES, INC. Topic: N/APrion diseases are 100 percent fatal, there is no treatment available, and cannot be diagnosed prior to the occurrence of symptoms. There is a public health need and an enormous market for a screening test that can help protect the blood supply, screen live animals, and ensure food safety. We propose to develop and validate an innovative, highly sensitive screening method for the detection of the ...
STTR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health -
AN EXPANDED GENETIC INFORMATION SYSTEM
SBC: ERAGEN BIOSCIENCES, INC. Topic: N/ADESCRIPTION (provided by applicant): The DNA alphabet is not limited to the four standard nucleotides. Rather, twelve nucleobases forming six base pairs joined by mutually exclusive hydrogen bonding patterns are possible within the geometry of the Watson-Crick base pair. These form An Expanded Genetic Information System (Aegis), a new, "rule based" molecular recognition system that carries protein ...
STTR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health -
ENHANCED THERMAL TRANSFER DEVICE FOR BIOPRESERVATION
SBC: ORGAN RECOVERY SYSTEMS, INC. Topic: N/AEffective methods of preserving cells and tissues are essential for the established and emerging companies using cryopreservation as part of their production processes. Conventional freezing and thawing devices have low heat transfer efficiencies that cause non-uniform thermal processing in biological materials resulting in products with low and inconsistent cell viability. The development of an a ...
STTR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health -
NONCONTACT MEMBRANE PROTEIN PROBE
SBC: Prairie Technologies, Inc. Topic: N/AReading the conformational state of membrane proteins is central to understanding their role in cell signaling, to using them as sensor elements and for screening candidate drug compounds that are targeted toward this important class of biomolecules. While the patch clamp technique for doing this is ubiquitous, it does have significant limitations: two electrodes are required to measure current fl ...
STTR Phase I 2002 Department of Health and Human ServicesNational Institutes of Health