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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Monoclonal antibodies targeting novel sites of vulnerability in marburg virus glycoprotein

    SBC: Integrated Biotherapeutics, Inc.            Topic: NIAID

    Filoviruses, consisting of two major virus families including the ebolaviruses and marburgviruses (MARV and RAVV), cause periodic outbreaks of severe viral hemorrhagic fever with mortality rates as high as 90%. Since it is difficult to predict the species that would dominate future outbreaks, development of broadly protective therapeutics to prevent and manage future filovirus outbreaks is of high ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  2. DR?1-MOG as a Next-Generation Immunotherapy for Methamphetamine Use Disorder

    SBC: VIROGENOMICS BIODEVELOPMENT INC            Topic: R41

    Methamphetamine use disorder is associated with damage to regions of the brain that control cognitive and psychiatric functionOne third to one half of adults with methamphetamine use disorder experience cognitive impairments and other psychiatric symptoms that significantly impact treatment outcomesincreased relapse and lower treatment retention ratesMounting evidence demonstrates how immune facto ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Aminoglycosides with reduced ototoxicity via miRNA targeting

    SBC: NUBAD LLC            Topic: NIAID

    PROJECT SUMMARYAminoglycosides are one of the cheapest and well-known antibiotics in clinical use for over 70 years, but one of the major limitations in their use is their ototoxicity. We are developing fast and low cost methods to develop aminoglycosides with anti- ribosomal activities and reduced toxicity. In this project, we will identify novel aminoglycoside antibacterials, that show reduced o ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  4. Using Interactive Digital Media to Teach Cardiopulmonary Resuscitation to High School Students

    SBC: CORAM TECHNOLOGIES, INC.            Topic: 400

    Summary Abstract Out of hospital cardiac arrest affects overpeople in the U Sannuallybut onlysurviveBystander cardiopulmonary resuscitationCPRimproves survivalbut rates of training in the U Sare lowIt is recently required by law inU Sstates that high school students learn CPRHoweverthere is great variability nationwide in howby whomand when students are taughtAdditionallycurrent methods of teachin ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  5. Mobile Peer Support for Opioid Use Disorders: Refinement of an Innovative Machine Learning Tool

    SBC: BEACON TECH INC            Topic: R41

    PROJECT SUMMARY This proposal develops a novelartificial intelligenceAIenabledmobile treatment delivery method that fulfills the need for a robustsecuretechnology based peer support platform to support patients with opioid use disordersOUDsThe majority of individuals with OUDs in the United States do not receive any formal substance use treatmentand growing evidence suggests that many OUD patients ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  6. Coherence Gated Doppler for Dentistry

    SBC: CREATV MICROTECH INC            Topic: NIDCR

    AbstractIf there were a simple and accurate means totake the pulseof a toothi efunctionally similar to a pulse oximeter that could be clipped on a tooth rather than the tip of a fingerthe quality and cost of dental care would be significantly improvedThe ability to measure dental pulp blood flow provides the most direct means to determine the viability of a tooth and is a vital piece of informatio ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  7. Optimization of microparticle-based topical treatments for treating erectile dysfunction in patients refractory to oral PDE5 inhibitors

    SBC: Zylo Therapeutics Inc.            Topic: 400

    Radical prostatectomyRPis a commonly used treatment option for localized prostate cancerUnfortunatelythe procedure carries a risk of post surgical complications including a high risk of erectile dysfunctionEDThe main pathophysiological mechanism behind this is neuropraxia in which surgery either directly damages the cavernous nervesCNor does so indirectly through activation of an inflammatory resp ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  8. Development of a Novel Bio-Adhesive Mesh System for Abdominal Hernia Repair

    SBC: CIRCA BIOSCIENCE LLC            Topic: 300

    Development of a Novel Bio Adhesive Mesh System for Abdominal Hernia Repair Project Summary Abstract This project proposes the development of a novel mesh adhesive system for abdominal hernia repair utilizing surface modification of polymer surgical mesh to allow for improved tissue fixation with a poloxamine hydrogel adhesiveMore thanmillion Americans undergo hernia repair with surgical mesh each ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  9. Oral Enzymatic Management of Phenylketonuria

    SBC: ABRI SCIENCE, LLC            Topic: 300

    PhenylketonuriaPKUis a genetic disorder of metabolism characterized by a pathological elevation of phenylalaninePhein the body stemming from a dysfunctional phenylalanine hydroxylase enzymePAHThe resulting high concentrations of Phexcan result in severe intellectual disabilitybehavioral problemsand neurological deficitse gseizuresStrict control of dietary Phe is the primary treatment for PKU curre ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
  10. Identifying hereditary cancer patients in low-resource community cancer settings using an innovative informatics solution

    SBC: SGgenomics, Inc.            Topic: 101

    PROJECT SUMMARYHereditary cancer risk assessment in low resource community cancer settings is a signi cant unmet clinical needUnfortunatelymost community cancer clinics do not have adequate access to genetics expertise and patients are not systematically assessed for hereditary riskNew cost e ective and practical approaches are needed to assess and identify patients at risk for hereditary cancer c ...

    STTR Phase I 2019 Department of Health and Human ServicesNational Institutes of Health
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