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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Advanced Tracking Techniques for FOPEN GMTI Radars

    SBC: ALPHATECH, INC.            Topic: N/A

    The utility of continuously tracking vehicles in a battlefield has been demonstrated during the Gulf War and other recent conflicts. However, the ability to achieve reliable continuous tracking in many environments will require the use of FOPEN radar andefficient use of sensor resources. In this effort we extend current research to include heterogeneous terrain and apply this model to simulations. ...

    STTR Phase I 2001 Department of DefenseDefense Advanced Research Projects Agency
  2. Aerosolized hyaluronic acid as a treatment for emphysema

    SBC: EXHALE THERAPEUTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Chronic obstructive pulmonary disease afflicts 12-14 million people in the US and in an advanced form, emphysema, disables 2 million and ultimately leads to death. No approved, existing treatment can arrest emphysema's progressive destruction of the lung. Exhale Therapeutics, Inc intends to develop and commercialize aeros ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  3. A Millimeter-wave Tunable Cavity for Ultra-sensitive Solids and Liquids DNP-NMR at Low Budget

    SBC: DOTY SCIENTIFIC, INC.            Topic: NIA

    ? DESCRIPTION (provided by applicant): NMR is probably the most powerful and widely used analytical technique for structure determination and function elucidation of molecules of all types, but it suffers from low sensitivity, particularly for insoluble biological macromolecules. Dynamic Nuclear Polarization (DNP) with Magic Angle Spinning (MAS) has recently demonstrated S/N gains exceeding t ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. A Novel Bioresorbable Septal Occluder

    SBC: Nmt Medical, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): There is a significant body of evidence that links patent foramen ovale with cryptogenic stroke. Furthermore, closure of the patent foramen ovale has been shown to reduce the risk of stroke in high-risk patients. Closure of a patent foramen ovale is currently done by percutaneous device closure using a septal occluder. This procedure has become standard for ver ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  5. A P. falciparum MSP1 p42/QS-21 malaria vaccine

    SBC: Agenus Inc.            Topic: N/A

    DESCRIPTION: (Adapted from Applicant's Abstract) Malaria is a disease which affects more than 300 million people each year and is fatal for 1.5 million. The overall objective of this STTR Phase I project is to produce a cGMP malaria vaccine consisting of the 42 kDa C-terminal polypeptide of P. falciparum merozoite surface protein-1 (MSP1.42) to be formulated with ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  6. A Portable Efficient Phrase Translation System

    SBC: Voice Signal            Topic: ST051001

    This proposal combines two technologies to create an efficient, effective translation device. We propose coupling commercially available cell phone basic technology from Voice Signal with approximate search from the International Computer Science Institute through an API on a portable device to demonstrate multi-lingual approximate phrase searching and translation on COTS devices.

    STTR Phase I 2005 Department of DefenseDefense Advanced Research Projects Agency
  7. A smart needle guide template for MRI-guided transperineal prostate biopsy

    SBC: PHYSICAL SCIENCES INC.            Topic: NCI

    DESCRIPTION (provided by applicant): Physical Sciences Inc. (PSI) and the Surgical Navigation and Robotics Laboratory (SNR) at Brigham and Women's Hospital (BWH) propose to develop and test a Smart Template to guide transperineal targeted prostate biopsiesand subsequent therapy under magnetic resonance imaging (MRI). The project aims to solve the problem of poor diagnostic yield in prostate b ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. AutoRegister: A system for enhancing the accuracy of tumor change detection

    SBC: CORTICOMETRICS LLC            Topic: NCI

    DESCRIPTION (provided by applicant): This project proposes to build an integrated software-based system for enhancing the accuracy of tumor change detection. The intent of the system, called AutoRegister, which is to be deployed on a clinical magnetic resonance imaging (MRI) scanner platform, is to automate the alignment of a patient's brain scan with that of a prior scan, such that subseque ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Behavioral Intervention in Autism

    SBC: PRAXIS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Autism Spectrum Disorder (ASD) is a complex neurological disorder that typically appears before the age of 3 and immediately and profoundly affects a young child's ability to communicate, develop language, form social relationships and respond appropriately to environmental cues. Whereas all children with developmental disabilities receive some form of federall ...

    STTR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  10. BEHAVIORAL TECHNOLOGY FOR INSTRUCTIONAL READINESS

    SBC: PRAXIS, INC.            Topic: N/A

    This application seeks support for an STTR Phase I project to develop and study a computer software product for computer-managed evaluation and instruction with children who have severe mental retardation, autism, and other intellectual disabilities. The product is primarily targeted to those students who lack the behavioral prerequisites to participate in ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
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