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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Uniform, High Intensity X-ray Source for Blood Irradiation

    SBC: National Nanomaterials, Inc            Topic: 22a

    There is an ongoing effort to replace high activity radioactive sources that could pose a risk for use as terrorist weapons with non-radioisotope based technologies. Currently radioactive sources serve a number of critical needs including the treatment and diagnosis of disease, inspection and certification of critical mechanical structures, the sterilization of food and medical products, ...

    STTR Phase I 2014 Department of Energy
  2. Methodology for Attrition Evaluation of Oxygen Carriers in Chemical Looping Systems

    SBC: ENVERGEX LLC            Topic: 11d

    This Small Business Innovation Research (STTR) project targets the development of novel methodology for the evaluation of a wide range of oxygen carriers, in particular, their attrition resistance, under conditions that broadly account for the process requirements of coal-based chemical looping systems. Existing test protocols and procedures for the evaluation of granular materials do not accurate ...

    STTR Phase I 2014 Department of Energy
  3. Ionomer Dispersion Impact on Advanced Fuel Cell and Electrolyzer Performance and Durability

    SBC: Giner, Inc.            Topic: 09b

    The ionomer dispersion technology invented at LANL has demonstrated great potential to significantly improve the lifetime of proton exchange membrane (PEM) fuel cells via accelerated stress tests. However, more validation and improvements are needed to make this technology commercially viable for PEM fuel cell-based hydrogen vehicles. The overall project is to further improve and validate this ion ...

    STTR Phase I 2014 Department of Energy
  4. Automated process for the fabrication of highly customized thermally insulated cladding systems

    SBC: Polycel Inc            Topic: 03b

    Adding thermal insulation to existing building envelopes can be an effective way of reducing building energy use. While most thermal insulation materials are affordable, the cost of installing thermal insulation into existing buildings can be expensive. Real facades are also characterized by many unique elements that affect their rated thermal performance, such as corners, windows, d ...

    STTR Phase I 2014 Department of Energy
  5. Development of small near-infrared laser system capable of improving immune respo

    SBC: SEMINEX CORPORATION            Topic: NIAID

    DESCRIPTION (provided by applicant): The broad and long-term objective of this project is to amplify the effectiveness of vaccines without the use of chemical or biological adjuvants. We will address this objective by demonstrating the feasibility for small laser- based devices to enhance responses to intradermal vaccination. A number of investigators have shown that a promising new way to make va ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Ex vivo purging strategy for treatment of multiple myeloma

    SBC: Dnatrix, Inc            Topic: NCI

    DESCRIPTION (provided by applicant): The ultimate goal of this application is to develop a novel ex vivo purging method using myxoma virus (MYXV), a rabbit-specific poxvirus, to improve the clinical outcomes in treatment of multiple myeloma (MM). MM is aclonal plasma cell malignancy that has to date resisted essentially all therapeutic strategies. Currently, the standard of care for patients wit ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Therapeutic Utility of renalase and renalase peptides in cisplatin-mediated renal

    SBC: BESSOR PHARMA, LLC            Topic: NCI

    DESCRIPTION (provided by applicant): Cisplatin is a cornerstone therapy for a number of cancers including testicular, bladder, ovarian and lung. It is also used to treat cancers in children. In all cases there is a high incidence of acute kidney injury (AKI) that can also lead to later stage kidney damage. This risk limits its use. We have found in pilot studies that renalase, or peptide fragment ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Non-ATP competitive inhibitors of cyclin dependent kinases as cancer therapeutics

    SBC: PPI PHARMACEUTICALS, LLC            Topic: NCI

    DESCRIPTION (provided by applicant): As cancer is one of the leading causes of death in the United States with some sub-types remaining essentially untreatable, expansion of available drug targets will provide significant new options for the development ofmore effective antineoplastic agents. The major goal of this project is to apply a unique drug discovery strategy to cancer drug development. Th ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. DNP Polarization Agents for Real-Time Metabolic Imaging and Clinical Diagnosis

    SBC: DYNUPOL, INC.            Topic: NCI

    Project Summary / Abstract Although standard MRI techniques provide valuable structural insight, a related technique known as magnetic resonance spectroscopy (MRS) adds powerful real-time metabolic information about the tissues under study. MRS provides early detection of disease, monitoring treatment efficacy, and, in the case of cancer, a dramatic reduction in unnecessary biopsies. However, bro ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Developing Inhibitors of the STARS/SRF Pathway for Treatment of Type 2 Diabetes

    SBC: Jenesis Biosciences LLC            Topic: NIDDK

    DESCRIPTION (provided by applicant): Type 2 diabetes (T2D) has reached epidemic proportions in the United States, affecting an estimated 8.3% of the population. Unfortunately, the majority of individuals with diabetes continue to have suboptimal control ofglucose, therefore new and improved approaches to prevention and treatment are sorely needed. Dr. Mary Elizabeth Patti's laboratory at the ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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