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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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A Millimeter-wave Tunable Cavity for Ultra-sensitive Solids and Liquids DNP-NMR at Low Budget
SBC: DOTY SCIENTIFIC, INC. Topic: NIA? DESCRIPTION (provided by applicant): NMR is probably the most powerful and widely used analytical technique for structure determination and function elucidation of molecules of all types, but it suffers from low sensitivity, particularly for insoluble biological macromolecules. Dynamic Nuclear Polarization (DNP) with Magic Angle Spinning (MAS) has recently demonstrated S/N gains exceeding t ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
A novel drug detection assay using fluorescent biosensor technology
SBC: GLSynthesis Inc. Topic: 300DESCRIPTION provided by applicant This phase project has as its overall objectives to design engineer optimize and implement a novel genetically encoded fluorescent drug sensor FDS based on F rster Resonance Energy Transfer FRET by exploiting conformational rearrangements induced by drug interactions with human serum albumin SA SA is uniquely suited for a general drug sensor beca ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
A smart needle guide template for MRI-guided transperineal prostate biopsy
SBC: PHYSICAL SCIENCES INC. Topic: NCIDESCRIPTION (provided by applicant): Physical Sciences Inc. (PSI) and the Surgical Navigation and Robotics Laboratory (SNR) at Brigham and Women's Hospital (BWH) propose to develop and test a Smart Template to guide transperineal targeted prostate biopsiesand subsequent therapy under magnetic resonance imaging (MRI). The project aims to solve the problem of poor diagnostic yield in prostate b ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
ASTROCYTE ACTIVATION BY SMALL MOLECULE P2Y1 AGONISTS FOR TREATMENT OF TBI
SBC: ASTROCYTE PHARMACEUTICALS INC. Topic: 105DESCRIPTION provided by applicant Traumatic brain injuries TBI are an area of significant unmet need with no approved therapeutics and a national burden of $ billion annually Astrocyte Pharmaceuticals is developing a small molecule pharmaceutical agent that would be administered by intravenous injection by emergency responders or a medical professional within hours of injury to limit n ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
A Structural Brain MRI Dementia Forecast Tool
SBC: CORTICOMETRICS LLC Topic: NIADESCRIPTION provided by applicant Alzheimerandapos s disease AD the most common type of dementia is a devastating disease with no available treatment or prevention The current lifetime risk for a year old individual is estimated to be around Given current projections over million individuals will be diagnosed with Alzheimerandapos s disease by As the development of the ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
AutoRegister: A system for enhancing the accuracy of tumor change detection
SBC: CORTICOMETRICS LLC Topic: NCIDESCRIPTION (provided by applicant): This project proposes to build an integrated software-based system for enhancing the accuracy of tumor change detection. The intent of the system, called AutoRegister, which is to be deployed on a clinical magnetic resonance imaging (MRI) scanner platform, is to automate the alignment of a patient's brain scan with that of a prior scan, such that subseque ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Cloud quantitative imaging for whole-body tumor burden in neurofibromatoses
SBC: IQ MEDICAL IMAGING LLC Topic: 102DESCRIPTION provided by applicant The neurofibromatoses NFs including NF NF and schwannomatosis are a group of autosomal dominant neurogenetic disorders characterized by a predisposition in virtually of patients to develop multiple nerve sheath tumors The determination of tumor burden on magnetic resonance imaging MRI images is crucial for the management of NF patients which is ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Developing Inhibitors of the STARS/SRF Pathway for Treatment of Type 2 Diabetes
SBC: Jenesis Biosciences LLC Topic: NIDDKDESCRIPTION (provided by applicant): Type 2 diabetes (T2D) has reached epidemic proportions in the United States, affecting an estimated 8.3% of the population. Unfortunately, the majority of individuals with diabetes continue to have suboptimal control ofglucose, therefore new and improved approaches to prevention and treatment are sorely needed. Dr. Mary Elizabeth Patti's laboratory at the ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Development of PAR2 Pepducins for the Treatment of Atopic Dermatitis
SBC: OASIS PHARMACEUTICALS, LLC Topic: NIAMSDESCRIPTION provided by applicant Atopic dermatitis AD or severe eczema is a very common life long skin disease with of adults in the US requiring systemic therapy Clinical manifestations of AD include multiple inflamed lesions erosions accompanied by lichenification thick leathery skin fibrotic papules and severely dry skin with increased susceptibility to infection A major uncont ...
STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health -
Development of Peptide Antibiotic Nucleic Acids
SBC: NUBAD LLC Topic: NIAIDDESCRIPTION provided by applicant One of the challenges of research in infectious diseases is to find ways to use the increasing knowledge of the mechanisms underlying disease transformation and progression to develop novel therapeutic strategies for diseases such as increasing menace of bacterial infections Targeting specific RNA such as rRNA which are involved in proliferation and survival ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health