Award Data

Precision Combustion, Inc. (PCI) is developing a regenerable high efficiency filter technology for direct removal of gaseous pollutants such as VOCs and CO2 from indoor air. In addition to controllably improving indoor air quality (IAQ), the direct removal of these pollutants will reduce the requirement for building ventilation with outdoor make-up air currently used to dilute the concentration of ...

Precision Combustion, Inc. proposes to develop functionalized nanocarbons as an improved high capacity, regenerable filter for VOCs and other gaseous contaminants, tailored to the purpose of sorption of a broad array of air contaminants from indoor or industrial sources. The company’s sorbent offers to overcome limitations to air purification inherent to other commercial sorbents, including loss ...

The US DoD requires robust ways of neutralizing threats posed by hostile powers and terrorist organizations that may be in possession of dangerous weapons of mass destruction (WMDs). Unfortunately, the weapons currently available to the DoD do not offer a way for the WMD to be destroyed without risking the spread of that material throughout the area. The strategy for the defeat of biological weapo ...

The overall objective of this proposal is to develop an in vitro process by which cancer stem cells CSC can be isolated from primary human tumor biopsies or tissues expanded without losing critical elements of stem cell qualities and then used for preclinical and clinical applications During this fast track proposal KIYATEC will employ an integrated functional and unbiased scientific strate ...

The overall goal of this collaborative project between SibTech Inc PI Backer J and Johns Hopkins University PI Pomper M is clinical development of efficient and cost effective anti angiogenic Lu radiopharmaceutical scV Lu for VEGF receptor mediated targeting of angiogenic tumor vasculature Current very expensive anti angiogenic compounds induce transient regression of tumor vascula ...

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DESCRIPTION provided by applicant Although tyrosine phosphorylation is an important controlling element in cell signaling no tRNA suppressor for phosphotyrosine pTyr incorporation has yet been made We propose to use directed molecular evolution of several aminoacyl tRNA synthetases aaRSs to identify mutations that enable binding of pTyr to the aaRS Specifically ATP molecules will be att ...

DESCRIPTION provided by applicant The EPA maintains a Toxics Release Inventory of over toxic chemicals that are disposed or released from more than industrial sites in the United States The Department of Health and Human Services and USDA maintain a list of over select agents and toxins that pose a severe risk to both human animal and plant health These compounds represent only ...

DESCRIPTION provided by applicant Clean water is one of the most basic societal needs in the world Few situations incite more public outcry than when a community learns that their drinking water has been tainted Two of the biggest threats to groundwater quality in the U S are contamination from either chlorinated solvents or petroleum Left unattended the size and scope of the problems asso ...