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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Advanced Tools for Mammalian Genome Engineering

    SBC: CARRYGENES BIOENGINEERING LLC            Topic: ST13B001

    Recent advances in mammalian artificial chromosome design and engineering offer an alternative to existing methodologies for cellular bioengineering and address unmet needs to bioengineer more complex functionalities into human cells for subsequent commer

    STTR Phase I 2014 Department of DefenseDefense Advanced Research Projects Agency
  2. Functional MRI and Behavioral Markers of Successful Service Dogs

    SBC: Dog Star Technologies LLC            Topic: ST13A001

    In Phase II, we will partner with CCI to deploy our fMRI protocol in 50 of their dogs entering advanced training, and determine neural biomarkers that predict successful completion of the course and placement with a human. Because MRI is expensive and lab

    STTR Phase II 2014 Department of DefenseDefense Advanced Research Projects Agency
  3. Functional Imaging to Develop Outstanding Service-Dogs (FIDOS)

    SBC: iK9, LLC            Topic: ST13A001

    IK9, LLC, and Auburn University shall collaborate in the development of prototype procedures for conducting cognitive neuroscience studies employing fMRI imaging of the brains of unrestrained dogs while they are in an awake and responsive state. IK9 is an international leader in innovative working dog training, handler instruction, and K9 team operations and management. Auburns Canine Detection ...

    STTR Phase II 2014 Department of DefenseDefense Advanced Research Projects Agency
  4. NMDA Receptor Subtype Selective Modualtors as Alzheimer's Disease Therapeutics

    SBC: NEUROP, INC.            Topic: NIA

    DESCRIPTION (provided by applicant): Alzheimer's disease (AD) is a devastating neurodegenerative disorder. One of the few drugs used to treat AD is memantine, which inhibits N-methyl-d-aspartate receptors (NMDARs), glutamate receptor subtypes found at nearly all vertebrate excitatory synapses. NMDARs are critically involved in many aspects of nervous system function, including learning and me ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Enable Early and Sensitive In Vivo Detection of Liver Metastasis by Protein-based

    SBC: INLIGHTA BIOSCIENCES L.L.C.            Topic: NCI

    DESCRIPTION (provided by applicant): The major barriers limiting the application of MRI to detect small liver lesions and metastasis at the early stage and patient selection for targeted therapy based on molecular imaging of disease biomarkers, are due tothe lack of desired MRI contrast agents capable of enhancing the contrast between normal liver tissues and tumors with high relaxivity, tumor tar ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Non-ATP competitive inhibitors of cyclin dependent kinases as cancer therapeutics

    SBC: PPI PHARMACEUTICALS, LLC            Topic: NCI

    DESCRIPTION (provided by applicant): As cancer is one of the leading causes of death in the United States with some sub-types remaining essentially untreatable, expansion of available drug targets will provide significant new options for the development ofmore effective antineoplastic agents. The major goal of this project is to apply a unique drug discovery strategy to cancer drug development. Th ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Mucins in the Diagnosis and Prognosis of Pancreatic Diseases

    SBC: Sanguine Diagnostics And Therapeutics, Inc.            Topic: NCI

    DESCRIPTION (provided by applicant): Due to its asymptomatic nature and lack of methods for early detection, gt 80% of pancreatic cancer (PC) patients present with an unresectable primary tumor with distant metastasis at the time of diagnosis. While the overall 5 year survival rate of pancreatic cancer is dismal, significantly better outcomes have been reported for smaller tumors detected at an e ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. A Millimeter-wave Tunable Cavity for Ultra-sensitive Solids and Liquids DNP-NMR at Low Budget

    SBC: DOTY SCIENTIFIC, INC.            Topic: NIA

    ? DESCRIPTION (provided by applicant): NMR is probably the most powerful and widely used analytical technique for structure determination and function elucidation of molecules of all types, but it suffers from low sensitivity, particularly for insoluble biological macromolecules. Dynamic Nuclear Polarization (DNP) with Magic Angle Spinning (MAS) has recently demonstrated S/N gains exceeding t ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. A Doppler Simulator for Vascular Ultrasound Training

    SBC: SHEEHAN MEDICAL LLC            Topic: NIBIB

    We will develop and test a simulator of diagnostic vascular ultrasound for use in medical education and professional certification. The simulator will include not only two-dimensional (2D) images but also Doppler spectral waveforms to simulate duplex ultrasound scanning. The rationale is that education in diagnostic ultrasound has traditionally been based on an extended duration of clinical exposu ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. High Intensity Ultrasonic Device for Mitigating Neonatal Perioperative Bleeding

    SBC: BIODESIGN RESEARCH AND DEVELOPMENT, LLC            Topic: NHLBI

    DESCRIPTION (provided by applicant): Congenital heart disease (CHD) ranges from benign lesions to life-threatening structural abnormalities. While benign lesions may resolve without intervention, severe structural lesions require complex pediatric cardiacsurgery. The reconstruction of the aortic arch in children is a complex repair in which perioperative bleeding i a significant, important and fre ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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