Award Data

This Small Business Technology Transfer Research (STTR) Phase I project will leverage past National Science Foundation Funded research to prove that a blind/low vision user can receive practical navigation and interaction information about their environment from a multimodal thermogram (thermal image) interface on a smartphone. There are no practical assistive technologies for blind or low vision ...

This STTR Phase I project proposes to develop an interactive computer game to promote interest in science, technology, engineering, and math (STEM) for high school students. The game will use NSF-funded technologies to teach students how to program and control robots while simultaneously maintaining student interest through the entertainment of playing a real time strategy (RTS) game. The proposed ...

This Small Business Technology Transfer Research (STTR) Phase I project will develop innovative sensors based on vertically aligned carbon nanotube (CNT) diode structures to increase the range and performance of wireless microelectromechanical systems (MEMS) sensors in high-temperature environments. Currently, wireless sensors are limited by the need to protect the electronics from the sensor envi ...

This Small Business Innovation Research (SBIR) Phase I project will enable development of pulsed laser micro polishing equipment and the software needed to use and control the equipment. To obtain a desired level of polishing (a mirror finish for example), many decisions must be made such as the path of the polishing laser over a surface to be polished, the speed with which the laser beam moves, t ...

DESCRIPTION (provided by applicant): Alzheimer's disease (AD) is a devastating neurodegenerative disorder. One of the few drugs used to treat AD is memantine, which inhibits N-methyl-d-aspartate receptors (NMDARs), glutamate receptor subtypes found at nearly all vertebrate excitatory synapses. NMDARs are critically involved in many aspects of nervous system function, including learning and me ...

DESCRIPTION (provided by applicant): The major barriers limiting the application of MRI to detect small liver lesions and metastasis at the early stage and patient selection for targeted therapy based on molecular imaging of disease biomarkers, are due tothe lack of desired MRI contrast agents capable of enhancing the contrast between normal liver tissues and tumors with high relaxivity, tumor tar ...

DESCRIPTION (provided by applicant): As cancer is one of the leading causes of death in the United States with some sub-types remaining essentially untreatable, expansion of available drug targets will provide significant new options for the development ofmore effective antineoplastic agents. The major goal of this project is to apply a unique drug discovery strategy to cancer drug development. Th ...

DESCRIPTION (provided by applicant): This project proposes to develop and evaluate a hand rehabilitation system for chronic hemiparetic stroke survivors that have lost their ability to full control their hand. Stroke is the leading cause of adult disability, and is the third leading cause of death in the United States. Stroke survivors often face a significant loss of functional motor control in ...

DESCRIPTION (provided by applicant): Due to its asymptomatic nature and lack of methods for early detection, gt 80% of pancreatic cancer (PC) patients present with an unresectable primary tumor with distant metastasis at the time of diagnosis. While the overall 5 year survival rate of pancreatic cancer is dismal, significantly better outcomes have been reported for smaller tumors detected at an e ...

? DESCRIPTION (provided by applicant): NMR is probably the most powerful and widely used analytical technique for structure determination and function elucidation of molecules of all types, but it suffers from low sensitivity, particularly for insoluble biological macromolecules. Dynamic Nuclear Polarization (DNP) with Magic Angle Spinning (MAS) has recently demonstrated S/N gains exceeding t ...