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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Rapid DNA extraction from gels
SBC: DIFFINITY GENOMICS, INC. Topic: NHGRIDESCRIPTION (provided by applicant): Extraction of DNA from gels following electrophoresis is widely used to obtain purified size selected DNA fragments from mixtures. The DNA thus obtained is used for cloning and sequencing reactions. Gel extraction is part of next generation sequencing protocols that are becoming the primary source of genetic information. That information is widely used in trans ...
STTR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health -
Rapid purification following enzyme-catalyzed nucleic acid reactions
SBC: DIFFINITY GENOMICS, INC. Topic: NHGRIDESCRIPTION (provided by applicant): Biochemical reactions used in the analysis and manipulation of DNA are important for many applications including forensics, diagnostic genetic testing and biomedical research. Enzymatic reactions to cut and insert DNA into cloning sites underpin many strategies for disease research and for use of microorganisms to express important proteins with medical value. ...
STTR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health -
Assessing the Bite Counter as a Tool for Food Intake Monitoring
SBC: BITE TECHNOLOGIES, LLC Topic: NIDDKDESCRIPTION (provided by applicant): This proposal is in response to PA-07-436 Bioengineering Approaches to Energy Balance and Obesity (STTR [R41/R42]) . In this project we will assess a wrist-worn bite counter for monitoring food intake. Specifically,we will evaluate the device across different foods, liquids, utensils and containers to measure its utility for monitoring eating. We will create ...
STTR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health -
Science Take-Out Kits for Environmental Health Education
SBC: Science Take-Out, LLC Topic: NIEHSDESCRIPTION provided by applicant Nearly percent of death and disease worldwide is linked to environmental factors WHO therefore it is critical that the general public has basic understanding of how the environment affects their health and how they might protect themselves against environmental exposures Unfortunately environmental health content is typically covered on a very ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
A Millimeter-wave Tunable Cavity for Ultra-sensitive Solids and Liquids DNP-NMR at Low Budget
SBC: DOTY SCIENTIFIC, INC. Topic: NIA? DESCRIPTION (provided by applicant): NMR is probably the most powerful and widely used analytical technique for structure determination and function elucidation of molecules of all types, but it suffers from low sensitivity, particularly for insoluble biological macromolecules. Dynamic Nuclear Polarization (DNP) with Magic Angle Spinning (MAS) has recently demonstrated S/N gains exceeding t ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Novel Focal Adhesion Kinase autophosphorylation inhibitors against pancreatic cancer
SBC: CUREFAKTOR PHARMACEUTICALS, LLC Topic: NCIDESCRIPTION (provided by applicant): Due to the absence of effective therapies, pancreatic cancer is the fourth leading cause of cancer deaths in both men and women. This study focuses on the development of new small molecule inhibitors targeting Focal Adhesion Kinase against pancreatic cancer. Focal Adhesion Kinase (FAK) has been shown to play an important role in tumor cell survival, including p ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Evaluation of TRB-N0224, a Proprietary Chemically-Modified Curumin, for the Treat
SBC: TRAVERSE BIOSCIENCES, INC. Topic: NIADESCRIPTION (provided by applicant): Traverse Biosciences Inc. is a pre-clinical stage drug development company working to commercialize new chemical entities which act to resolve inflammatory conditions through pleiotropic host-modulation of pathologically unrestrained matrix metalloproteinases (MMPs) and pro-inflammatory cytokines. The company's lead drug candidate, TRB-N0224, is a proprie ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Recombinant Botulinum Neurotoxin for Treatment of Spastic Disorders
SBC: Cytodel, Inc. Topic: NINDSDESCRIPTION (provided by applicant): Botulinum neurotoxin (BoNT) is the active ingredient in pharmaceutical products like Botox(R) (Allergan), which FDA has approved for therapeutic and aesthetic indications. Because of its inherent toxicity,the dose of BoNT required to treat spasticity disorders in large muscle groups is uncomfortably close to the toxic dose range. ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Development and in vitro validation of therapy for mucopolysaccharidosis III
SBC: Phoenix Nest Inc. Topic: 105DESCRIPTION provided by applicant Sanfilippo disease mucopolysaccharidosis type III MPS III is a devastating neurodegenerative lysosomal storage disorder of childhood for which there is no cure or effective treatment available The fundamental cause of MPS III is an inherited mutation in one of the enzymes required to catabolize heparan sulfate HS a glycosaminoglycan which plays importa ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Using Structuring Interacting RNAs (sxRNAs) as microRNA Inhibitors
SBC: HocusLocus Inc. Topic: NIGMSDESCRIPTION (provided by applicant): We propose developing a trans-molecular RNA-switch for scientists to negatively affect the activity of endogenous microRNA for use as a molecular tool or therapeutic, an anti-miR. Since the discovery of miRNA, the creation of effective anti-miRs has been important, first to study and verify miRNA interactions, and, secondly, as a therapeutic tool. But, creating ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health