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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Low Control Voltage, Thin Film Multiferroic Tunable Devices for RF Applications

    SBC: QUINSTAR TECHNOLOGY, INCORPORATED            Topic: ST13B003

    We propose a novel suspended multiferroic thin film structure fabricated by semiconductor processing technologies as the basis for the approach to designing the multiferroic microstrip-based circuit elements such as tunable filters. The proposed approach

    STTR Phase I 2014 Department of DefenseDefense Advanced Research Projects Agency
  2. A High-Level Operator Abstraction for GPU Graph Analytics

    SBC: Royal Caliber            Topic: ST13B004

    We propose to build a framework around an operator formulation to enable rapid development of massively parallel solutions to large graph problems. Graph algorithms are expressed by a small number of operators that are applied to components of the graph.

    STTR Phase I 2014 Department of DefenseDefense Advanced Research Projects Agency
  3. Data-Parallel Analytics on Graphics Processing Units (GPUs)

    SBC: SYSTAP, LLC            Topic: ST13B004

    The proposed effort will extend existing proofs of concept and advanced research systems to: (a) provide an efficient, low-level, data-parallel runtime for graph processing on GPUs; (b) provide a high-level abstraction for writing graph analytics that are

    STTR Phase I 2014 Department of DefenseDefense Advanced Research Projects Agency
  4. New Class of Bright, Sharp, Tunable Near-Infrared Fluorophores for Flow Cyto

    SBC: Nirvana Sciences, Inc.            Topic: NIAID

    DESCRIPTION (provided by applicant): Polychromatic flow cytometry [FC] is one of the most powerful analytical techniques routinely used in immunology. Flow cytometry plays a critical role in several growing clinical applications: leukemia and lymphoma immunophenotyping for diagnosis and sub-categorization (now using 8-10 colors); in CD4/CD8 measurement in HIV-positive patients; and in HLA typing f ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Novel Small Molecule Therapeutics for Pancreatic Cancer

    SBC: ChemRegen Inc            Topic: NCI

    Project Summary/Abstract Developing new ways to treat pancreatic cancer is a significant challenge. Pancreatic cancer is the fourth leading cause of cancer-related deaths in the United States and results in an estimated 37,000 deaths/year. Pancreatic cancer therapeutic options are limited to surgery and/or combinations of chemotherapy and radiation. Unfortunately, late-stage diagnosis of pancreat ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. ChemoFilter: A Novel Catheter Device to Enable High-Dose Chemotherapy Treatment

    SBC: CHEMOFILTER, INC.            Topic: NCI

    Project Summary: Intravenous dosing of drugs for applications ranging from cancer chemotherapy to anti-microbials to lytic (blood clot dissolving) agents is limited by systemic toxicity. Currently, the only ways to remove drugs from the blood are throughnatural metabolism or costly impractical measures such as dialysis. Despite intense focus on targeted drug delivery agents, these therapies are c ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Developing Novel Therapies for Treating Breast-Cancer-Related Lymphedema

    SBC: ADEPTHERA, LLC            Topic: NCI

    DESCRIPTION (provided by applicant): Destruction of lymphatic vessels during the treatment of breast cancer by surgery and/or radiation therapy can lead to the development of secondary lymphedema. The breast-cancer-related lymphedema is associated with debilitating limb swelling, chronic inflammation, tissue fibrosis, and increased susceptibility to infection. It has been estimated that approximat ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Intra-procedure Deformable Ultrasound-MRI Fusion for Prostate Biopsies

    SBC: ZMK Medical Technologies, Inc.            Topic: NCI

    This proposal is a collaborative effort between Yale University and the medical device company Eigen to develop a more robust and accurate method for the deformable fusion of pre-operative magnetic resonance images (MRI) and intra-procedure trans-rectal ultrasound (TRUS) images to guide prostate biopsy. Prostate cancer is a major cause of death in the U.S. and biopsy is the gold-standard for its d ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Validation of a Novel Treatment for Glioblastoma

    SBC: CURTANA PHARMACEUTICALS, INC.            Topic: NCI

    ? DESCRIPTION (provided by applicant): The goal of this application is to study in vivo efficacy of CT102, a newly discovered inhibitor of the OLIG2 transcription factor in animal models of glioblastoma (GBM), a highly underserved area of pharmacotherapy. In this proposal, the experienced drug discovery group at Curtana Pharmaceuticals Inc. will conduct a pre-clinical evaluation of selectivity ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Targeting of Myc-Max dimerization for the treatment of cancer

    SBC: SORRENTO THERAPEUTICS, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): Myc is a key transcriptional regulator due to its critical role in many fundamental cellular processes, such as cell cycle progression and cell growth. Therefore, dysregulation of Myc expression can lead to disease, including cancer. Myc is overexpressed in many human tumors, and it is estimated that 1 in 7 cancer deaths in the United States are resultant of hi ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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