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Award Data
The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.
Download all SBIR.gov award data either with award abstracts (290MB)
or without award abstracts (65MB).
A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.
The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.
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Optimized lactoferrin for treatment of intracerebral hemorrhage
SBC: Pharmareview Corporation Topic: NINDSDESCRIPTION provided by applicant Intracerebral hemorrhage ICH is a major public health problem with highest mortality rate of all stroke subtypes and long term disability Since there are no available FDA approved therapies for ICH it is of enormous importance to establish effective treatment for this medical condition Following ICH the deposited blood is damaging initially via compression ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Catheter for Large Volume Intraparenchymal Brain Therapies
SBC: TWIN STAR TDS, LLC Topic: 105DESCRIPTION provided by applicant Neurodegenerative and malignant diseases of the central nervous system affect millions of Americans These diseases are often devastating and difficult to treat and effective drug delivery remains a significant challenge Infusion of drugs nto the brain parenchyma using convection enhanced delivery CED allows direct treatment of lesions circumventing the bl ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Nitric Oxide Microfluidic Sensor
SBC: CLINICAL SENSORS, INC. Topic: NIAIDDESCRIPTION provided by applicant This Small Business Innovation Research SBIR Phase I project aims to develop a microfluidic based nitric oxide NO sensor as an early sepsis risk assessment device Sepsis causes significant strain on the U S healthcare system consuming over $ billion annually due to extended hospital stays and significant morbidity and mortality Rapid diagnosis and in ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
RNA Detection as an Improved Diagnostic Assay for Human Leptospirosis
SBC: L2 DIAGNOSTICS LLC Topic: NIAIDDESCRIPTION provided by applicant Leptospirosis a zoonotic disease is an important public health problem worldwide It is caused by spirochete bacteria belonging to nine species and more than serovars of the genus Leptospira In the US there is increasing awareness of the importance of leptospirosis as the cause of disease among inner city populations military personnel and individuals ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
XRpro Radioactive Cesium Decorporation Agents
SBC: Icagen, Inc. Topic: NIAIDDESCRIPTION provided by applicant Caldera aims to develop an inexpensive stable selective decorporation decorp agent for cesium Cs Cs is easily obtainable by terrorists and treatments for exposures are Project Bioshield priorities for use in radiation nuclear emergencies high priority for DHHS NIH NIAID DAIT and a critical need for the Strategic National Stockpile S ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
A Multivalent Lyme Disease Vaccine Targeting Tick-Host-Pathogen Interactions
SBC: L2 DIAGNOSTICS LLC Topic: NIAIDDESCRIPTION provided by applicant This proposal seeks to develop a novel vaccine against Lyme disease by targeting Ixodes scapularis proteins critical for Borrelia burgdorferi transmission from the tick to mammalian host Earlier work has identified four tick proteins Salp TRE tHRF and TSLPI that facilitate different steps of spirochete transmission and immunity against these protein ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Development of Peptide Antibiotic Nucleic Acids
SBC: NUBAD LLC Topic: NIAIDDESCRIPTION provided by applicant One of the challenges of research in infectious diseases is to find ways to use the increasing knowledge of the mechanisms underlying disease transformation and progression to develop novel therapeutic strategies for diseases such as increasing menace of bacterial infections Targeting specific RNA such as rRNA which are involved in proliferation and survival ...
STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Antimicrobial Microbead Containing Topical Gel for Burn Wound Disinfection
SBC: LYNNTECH INC. Topic: NIAIDDESCRIPTION provided by applicant In the U S there are more than hospitalizations annually related to burn injury with more than of these admissions to the U S burn centers resulting in more than $ billion in healthcare costs Burn wounds may become infected through patient self infection from their own normal flora or by nosocomial infection between healthcare provider or fa ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
A novel broad-spectrum influenza vaccine
SBC: KJ BIOSCIENCES LLC Topic: NIAIDDESCRIPTION provided by applicant Influenza viruses constantly undergo antigenic changes which pose great challenges for development of vaccines against influenza epidemics as well as pandemics There are at least known subtypes of influenza A viruses which fall into two broad phylogenetic groups Current trivalent inactivated vaccines TIV H H and B for seasonal influenza are not suit ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health -
Developing a paper-based diagnostic test for sickle cell disease
SBC: HALCYON BIOMEDICAL, INC. Topic: NHLBIDESCRIPTION provided by applicant Sickle cell disease SCD is the most common hemoglobinopathy associated with significant life long morbidity and premature mortality Over children are born with SCD in sub Saharan Africa annually more than of them die in early childhood Most of these deaths could be prevented through simple and inexpensive prophylaxis if SCD was diagnosed soon ...
SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health