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The Award database is continually updated throughout the year. As a result, data for FY20 is not expected to be complete until September, 2021.

  1. Development and in vitro validation of therapy for mucopolysaccharidosis III

    SBC: Phoenix Nest Inc.            Topic: 105

    DESCRIPTION provided by applicant Sanfilippo disease mucopolysaccharidosis type III MPS III is a devastating neurodegenerative lysosomal storage disorder of childhood for which there is no cure or effective treatment available The fundamental cause of MPS III is an inherited mutation in one of the enzymes required to catabolize heparan sulfate HS a glycosaminoglycan which plays importa ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Development of an Antigen Capture Assay for Babesia microti

    SBC: Biopeptides, Corp            Topic: NIAID

    DESCRIPTION provided by applicant Babesia microti the primary etiologic agent of human babesiosis is a tick borne eukaryotic apicomplexan pathogen that is an increasing threat to the US public health Although B microti is primarily a tick borne pathogen it can be transmitted by transfusion of infected blood Despite the well recognized threat there is no FDA licensed test to screen donor ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Development of Peptide Antibiotic Nucleic Acids

    SBC: NUBAD, LLC            Topic: NIAID

    DESCRIPTION provided by applicant One of the challenges of research in infectious diseases is to find ways to use the increasing knowledge of the mechanisms underlying disease transformation and progression to develop novel therapeutic strategies for diseases such as increasing menace of bacterial infections Targeting specific RNA such as rRNA which are involved in proliferation and survival ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Live-attenuated ETEC Anti-Diarrhea Vaccine Construction via Synthetic Biology

    SBC: Codagenix Inc.            Topic: NIAID

    DESCRIPTION provided by applicant The development of vaccine to combat Enterotoxigenic E coli ETEC is vital given the pathogenandapos s global impact on million individuals annually however an entirely new non conventional approach is needed Field studies have suggested that inert antigen based vaccines to combat ETEC have andquot essentially no efficacyandquot Therefore a vaccin ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Picture Me Fit: Engaging Youth in Community-Based Prevention

    SBC: Prevention Strategies, LLC            Topic: 600

    DESCRIPTION provided by applicant Approximately one third of all U S adults and children are obese and at risk for a wide range of related chronic health conditions such as cardiovascular disease hypertension diabetes stroke osteoarthritis sleep apnea and certain types of cancer The Center for Disease Control and Prevention CDC and other expert resources recognize that although indivi ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. STTR Phase I: An Innovative Spray Pyrolysis Process for Producing Pyrochlore Catalysts

    SBC: PYROCHEM CATALYST COMPANY            Topic: MN

    The broader impact/commercial potential of this project is the development of a continuous and low-cost spray-pyrolysis process for making mixed metal oxide (MMO) materials that can be used in the petroleum and chemicals synthesis, precursors for solar panels, electrode materials, fuel cells, oxygen selective membranes, and chemical sensors. Of particular interest are crystalline pyrochlore mixed ...

    STTR Phase I 2014 National Science Foundation
  7. STTR Phase I: An ultrasonic device for rapid tomographic rodent tissue and vasculature imaging

    SBC: Sonovol, Inc.            Topic: BC

    This Small Business Innovation Research (SBIR) Phase I project will build a state of the art imaging tool for rodent disease quantification using ultrasound. Hundreds of millions of dollars in the US are spent annually on preclinical drug efficacy studies, as all candidate cancer therapeutics must be screened in rodents prior to any clinical trials. Academic and industry drug researchers make use ...

    STTR Phase I 2014 National Science Foundation
  8. STTR Phase I: A Simulated Anaerobic Digester Learning Tool

    SBC: BIODRILL TECHNICAL SOLUTIONS LLC            Topic: EA

    This SBIR Phase I project proposes to create an innovative educational game that engages secondary school students in learning about the science of anaerobic digestion and the business of biogas production. The Simulated Anaerobic Digester Learning Tool is a casual, simulation-based game that teaches students about the physicochemical operation of an anaerobic digester, as well as an entrepreneuri ...

    STTR Phase I 2014 National Science Foundation
  9. STTR Phase I: Fully Implantable, Ultra-Flexible Wireless Electrode Array for Brain Activity Mapping

    SBC: PREMITEC, INC.            Topic: EI

    This Small Business Technology Transfer Research (STTR) Phase I project proposes to develop and commercialize a fully implantable, integrated, ultra-flexible device for high-bandwidth bidirectional interface with the central nervous system aimed at brain-computer interfacing (BCI) and neurobiology research applications. The device will incorporate the implantable component of the multichannel wire ...

    STTR Phase I 2014 National Science Foundation
  10. STTR Phase I: Gabor-domain optical coherence microscopy for detection of defects in manufacturing

    SBC: LighTopTech Corp.            Topic: NM

    This Small Business Technology Transfer Phase I project will explore the applicability of a Gabor-domain optical coherence microscopy (GD-OCM) instrument to qualify materials during manufacturing processes. State-of-the-art interferometric instruments yield excellent resolution in depth, discriminating between different layers within a volume; optical microscopy offers high lateral resolution, but ...

    STTR Phase I 2014 National Science Foundation
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