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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Automated Monitoring of Chemotactic Cell Movement

    SBC: APPLIED BIOPHYSICS, INC.            Topic: N/A

    DESCRIPTION ( provided by applicant): The ECIS/taxis technology can detect cells that move to a small electrode through an agarose matrix by the resistance that they impart to an electrical circuit as they cover parts of the small electrode. This system is amenable to rapid throughput analysis of cell behavior in the presence of chemokines and other agents that ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  2. Combined Gene Therapy/Tissue Engineered Cartilage Repair

    SBC: TISSUEGENESIS, INC.            Topic: N/A

    DESCRIPTION (Verbatim from Applicant): The objective of this Phase I protocol is to develop a novel approach for the repair of articular cartilage using gene enhanced tissue engineering (GETE). Successful clinical repair of articular cartilage continues to be elusive. The current study seeks to repair articular cartilage defects using constructs containing cultured perio ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  3. NOVEL DEVICES FOR RAPID BLOOD COMPATIBILITY TESTING

    SBC: TRANSFUSION AND TRANSPLANTATION TECH            Topic: N/A

    The primary objective of these studies is to develop a novel device for rapid, cost-effective, and completely automated pretransfusion compatibility testing. This device will be of interest to Transfusion Medicine services and Blood Banks because it will improve testing throughput while cutting costs. Furthermore, applications are possible in other areas including platelet crossmatching and serolo ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  4. COMPUTERIZED STEREOCAMPIMETER TO MEASURE CENTRAL SCOTOMA

    SBC: OPTICOLOGY, INC.            Topic: N/A

    The proposed research intends to design and build an instrument of accurately measure centrally located pathological areas of non-vision, or central scotomas, within the 30 to 60 degrees field of vision. The new device is intended to serve as a supplement to commercially available automatic perimeters, which are known to be inaccurate when retinal defects are confined to the central field of visi ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  5. Design of EBVTK substrates to eradicate EBV+ tumors

    SBC: PHARMASSET, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The unique properties of aherpesvirus replicative enzymes have permitted development of antiviral drugs that are converted to cytotoxic compounds exclusively in virus-infected cells. Certain of these proteins form the basis for cytotoxic gene therapy (HSV-1TK and ganciclovir). Although the gherpesvirus EBV encodes similar ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  6. Virtual Reality Exposure Therapy for Social Phobias

    SBC: VIRTUALLY BETTER INC            Topic: N/A

    DESCRIPTION: This study will test the feasibility of virtual reality exposure (VRE) therapy for fear of public speaking. Recent studies suggest social phobia, which includes but is not limited to fear of public speaking, is one of the three most common psychological disorders, with lifetime prevalence rates of 10-13 percent of the general population. Discrete fear of ...

    STTR Phase I 2001 Department of Health and Human ServicesNational Institutes of Health
  7. POC 2-D Diffusion Assay for self-monitoring of BNP

    SBC: SENTILUS            Topic: NHLBI

    DESCRIPTION (provided by applicant): The objective of this STTR proposal is to develop a 2-D diffusion point-of-care assay (POC) for B-type natriuretic peptide (BNP). The primary goal of the proposed work is to create a test format that will allow patientswith chronic heart failure to quantitatively self-monitor serum levels of BNP. Determination of baseline level of BNP and changes in this level ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Science Take-Out Kits for Environmental Health Education

    SBC: Science Take-Out, LLC            Topic: NIEHS

    DESCRIPTION provided by applicant Nearly percent of death and disease worldwide is linked to environmental factors WHO therefore it is critical that the general public has basic understanding of how the environment affects their health and how they might protect themselves against environmental exposures Unfortunately environmental health content is typically covered on a very ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. A Millimeter-wave Tunable Cavity for Ultra-sensitive Solids and Liquids DNP-NMR at Low Budget

    SBC: DOTY SCIENTIFIC, INC.            Topic: NIA

    ? DESCRIPTION (provided by applicant): NMR is probably the most powerful and widely used analytical technique for structure determination and function elucidation of molecules of all types, but it suffers from low sensitivity, particularly for insoluble biological macromolecules. Dynamic Nuclear Polarization (DNP) with Magic Angle Spinning (MAS) has recently demonstrated S/N gains exceeding t ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. New generation of catheters for treatment of atrial fibrillation

    SBC: NOCTURNAL PRODUCT DEVELOPMENT, LLC            Topic: NHLBI

    DESCRIPTION (provided by applicant): Atrial fibrillation remains the most commonly occurring cardiac arrhythmia. It is associated with a lower quality of life and a higher rate of morbidity and mortality. Cryotherapy and radiofrequency catheter ablations for the purpose of eliminating atrial fibrillation have become a mainstream treatment option. They produce lesions that block the spread of elect ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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